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European Code Against Cancer, 5th edition – occupational exposures and cancer

Occupational exposure to cancer-causing agents is a major, yet preventable, contributor to cancer in Europe and globally. In the European Union (EU), cancer is responsible for nearly half of all work-related deaths, underscoring the critical need for prevention measures. Effective strategies typically involve regulatory and workplace measures aimed at reducing or eliminating exposure risks. Raisin

European Code Against Cancer, 5th edition – ultraviolet radiation, radon and cancer

The European Code Against Cancer (ECAC) provides evidence-based recommendations to help individuals reduce their cancer risk. For the 5th edition (ECAC5), recommendations on ultraviolet radiation (UVR) and indoor radon exposures were updated, and complementary recommendations for policymakers were introduced. UVR and radon are classified as carcinogenic to humans (group 1 carcinogens) in the Inter

Deep learning for automated alveolar cleft segmentation and bone graft volume estimation in cone-beam computed tomography imaging : a multicenter study

Objective To train and validate a deep learning-based diagnostic tool capable of accurately segmenting the alveolar cleft region and automatically estimating the required bone graft volume using cone-beam computed tomography (CBCT) imaging. Study Design Eighty-eight CBCT scans from patients with nonsyndromic unilateral clefts were divided into training (n = 45), validation (n = 10), and test (n =

Seeking support: insights into women’s mental health help-seeking behavior in Bangladesh

Introduction: Depression and anxiety are leading contributors to the global burden of disease among women yet help-seeking for mental health concerns remains limited in lower-middle-income countries. This study aimed to estimate the prevalence of anxiety, depression, and help-seeking behaviors, and to identify factors associated with the absence of help-seeking among ever-married women of reproduc

Validity of Self-Rating Questionnaires Used for Assessing Self-Disorders? A Systematic Review

Introduction: Self-disorders designate a group of nonpsychotic, trait-like, anomalous self-experiences. The “gold standard” for assessing self-disorders is largely considered to be the Examination of Anomalous Self-Experience (EASE). The EASE must be conducted as a semistructured interview, and it requires substantial knowledge of psychopathology and excellent interviewing skills. To bypass these

Different plasma biomarker patterns associated with coronary atherosclerosis in low- versus high-risk individuals – an observational cross-sectional study

Background and aims: Targeted omics techniques can be used to identify systemic blood biomarkers associated with coronary artery disease (CAD) and cardiovascular disease (CVD) events. Our aim was to study associations between plasma protein, metabolite biomarkers and subclinical CAD in a low and a high CVD risk population. Methods: The Swedish CArdioPulmonary bioImage Study (SCAPIS) was used for i

Patterns of Caffeine Use in Adolescents and Their Association with Sleep Quality : A Latent Class Analysis

Background: Although there is substantial evidence of the negative impact of caffeine use on sleep quality, few studies focus specifically on adolescents’ patterns of use. This study aimed to identify patterns of caffeine use among adolescents and analyze their association with sleep quality. Method: A cross-sectional study was conducted in southern Sweden including 1,404 adolescents aged 15–17 (5

Lymphovascular invasion is a dominant risk factor for lymph node metastasis in T2 rectal cancer

Background and study aims Surgical resection is standard treatment of T2 rectal cancer due to risk of concomitant lymph node metastases (LNM). Local resection could potentially be an alternative to surgical treatment in a subgroup of patients with low risk of LNM. The aim of this study was to identify clinical and histopathological risk factors of LNM in T2 rectal cancer. Patients and methods This

Drastic difference between hole and electron injection through the gradient shell of Cd: XSeyZn1- xS1- y quantum dots

Ultrafast fluorescence spectroscopy was used to investigate the hole injection in CdxSeyZn1-xS1-y gradient core-shell quantum dot (CSQD) sensitized p-type NiO photocathodes. A series of CSQDs with a wide range of shell thicknesses was studied. Complementary photoelectrochemical cell measurements were carried out to confirm that the hole injection from the active core through the gradient shell to

Good outcome scores and high satisfaction rate after primary total ankle replacement : 167 patients followed for 24 months in the Swedish Ankle Registry

Background and purpose — Total ankle replacement (TAR) is gaining popularity for treatment of end-stage ankle arthritis. Large patient-centered outcome studies are, however, few. Here, we report data from the Swedish Ankle Registry. Patients and methods — We examined outcomes after primary TAR in patients from the Swedish Ankle Registry using PROMs (Patient Reported Outcome Measures; generic: EQ-5

Photostability of the Oleic Acid-Encapsulated Water-Soluble CdxSeyZn1-xS1-y Gradient Core-Shell Quantum Dots

Composite systems where quantum dots (QDs) are combined with other nanomaterials (e.g., gold nanorods) in aqueous solutions have attracted broad attention - both for their potential in applications and for studies of fundamental processes. However, high-quality QDs are typically prepared in organic solvents, and the transfer of QDs to an aqueous phase is needed to create the desired QD composites.

Macroscopic Domains within an Oriented TQ1 Film Visualized Using 2D Polarization Imaging

Large-area self-assembly of functional conjugated polymers holds a great potential for practical applications of organic electronic devices. We obtained well-aligned films of poly[2,3-bis(3-octyloxyphenyl)quinoxaline-5,8-diyl-alt-thiophene-2,5-diyl] (TQ1) using the floating film transfer method. Thereby, a droplet of the TQ1 solution was injected on top of the surface of an immiscible liquid subst

QmeQ 1.0 : An open-source Python package for calculations of transport through quantum dot devices

QmeQ is an open-source Python package for numerical modeling of transport through quantum dot devices with strong electron-electron interactions using various approximate master equation approaches. The package provides a framework for calculating stationary particle or energy currents driven by differences in chemical potentials or temperatures between the leads which are tunnel coupled to the qu

Lead-Free, Air-Stable All-Inorganic Cesium Bismuth Halide Perovskite Nanocrystals

Lead-based perovskite nanocrystals (NCs) have outstanding optical properties and cheap synthesis conferring them a tremendous potential in the field of optoelectronic devices. However, two critical problems are still unresolved and hindering their commercial applications: one is the fact of being lead-based and the other is the poor stability. Lead-free all-inorganic perovskite Cs3Bi2X9 (X=Cl, Br,

Ultrasensitive and Fast All-Inorganic Perovskite-Based Photodetector via Fast Carrier Diffusion

Low trap-state density, high carrier mobility, and efficient charge carrier collection are key parameters for photodetectors with high sensitivity and fast response time. This study demonstrates a simple solution growth method to prepare CsPbBr3 microcrystals (MCs) with low trap-state density. Time-dependent photoluminescence study with one-photon excitation (OPE) and two-photon excitation (TPE) i

Tyrosine kinase inhibitor therapy-induced changes in humoral immunity in patients with chronic myeloid leukemia

Purpose: Tyrosine kinase inhibitors (TKIs) have well-characterized immunomodulatory effects on T and NK cells, but the effects on the humoral immunity are less well known. In this project, we studied TKI-induced changes in B cell-mediated immunity. Methods: We collected peripheral blood (PB) and bone marrow (BM) samples from chronic myeloid leukemia (CML) patients before and during first-line imat

Renal function and its association with blood pressure in Middle Eastern immigrants and native Swedes

BACKGROUND:: Iraqi-born immigrants residing in Sweden are at high risk for type 2 diabetes, obesity and hyperlipidemia compared with native Swedes. Paradoxically, hypertension is less prevalent in this immigrant population. The aim of this study was to investigate differences in renal function and further if differences in blood pressure (BP) levels were associated with differences across ethnicit

Novel risk genes for systemic lupus erythematosus predicted by random forest classification

Genome-wide association studies have identified risk loci for SLE, but a large proportion of the genetic contribution to SLE still remains unexplained. To detect novel risk genes, and to predict an individual's SLE risk we designed a random forest classifier using SNP genotype data generated on the "Immunochip" from 1,160 patients with SLE and 2,711 controls. Using gene importance scores defined b

Optical : In situ monitoring during the synthesis of halide perovskite solar cells reveals formation kinetics and evolution of optoelectronic properties

The formation mechanism and the evolution of optoelectronic properties during annealing of chlorine-derived methylammonium lead iodide (MAPbI3-xClx) are investigated in detail combining in situ and ex situ optical and structural characterization. Using in situ optical reflectometry we are able to monitor the evolution of the MAPbI3-xClx phase as a function of time and processing temperature. The f