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Syringe exchange has been suggested as a potential conduit to treatment for drug dependence, but this never has been documented in Europe. The primary aim was to compare the effectiveness of strength-based case management intervention against referral only to facilitate treatment attendance in a syringe exchange programme. We also assessed effectiveness of a syringe exchange programme for referral

Procedures for the initial management of children newly diagnosed with diabetes vary greatly worldwide and the evidence available is insufficient for conclusively determining the best process regarding hospital-based or home-based care. The aim of the study was to compare two different regimens for children with newly diagnosed type 1 diabetes; hospital-based care and hospital-based home care (HBH

Albumin (HSA) is the dominating protein in human plasma. Many bacterial species, especially streptococci, express surface proteins that bind HSA with high specificity and affinity, but the biological consequences of these protein-protein interactions are poorly understood. Group G streptococci (GGS), carrying the HSA-binding protein G, colonize the skin and the mucosa of the upper respiratory trac

BACKGROUND: Lung transplantation (LTx) is established as a life-saving treatment in end-stage lung disease. However, long-term survival is hampered by the development of chronic rejection, almost synonymous with bronchiolitis obliterans syndrome (BOS). The rejection is characterized by deposition of extracellular matrix in small airways. Fibroblasts/myofibroblasts are the main producers of extrace

In adults, the size of the left atria (LA) has important prognostic information. In obese adults, adolescents and children enlargement of LA have been observed. This has not been investigated on a population-based level in young children. We therefore assessed if total body fat mass (TBF), abdominal fat, and body fat distribution were related to LA diameter. Cross-sectional study of 244 children (

Social capital research has consistently shown positive associations between generalised trust and health outcomes over 2 decades. Longitudinal studies attempting to test causal relationships further support the theory that trust is an independent predictor of health. However, as the reverse causality hypothesis has yet to be empirically tested, a knowledge gap remains. The aim of this study, ther

INTRODUCTION Based on historical data, a decline in sperm counts during the years 1940-1990 has been suggested and aetiologically linked to a concomitant increase in the incidence of testicular cancer. This study, focusing on possible changes in sperm parameters among young Swedish men, during the past 10 years, was specifically designed in order to answer the question of whether there is a contin

People’s accumulated local capacity is increasingly recognized to be critical in enhancing disaster resilience and transformation. Nevertheless, citizens’ coping strategies are little known or documented, and hardly considered in city authorities’ and aid organizations’ work. Against this background, this study provides an overview and systematization of citizens’ strategies to cope with increasin

The aim of this paper is to present a model for creating a more coherent concept, designed to meet the demands of the multidisciplinary field of Sociology of Law. This model is built on an ontological analysis that can incorporate different perspectives. The suggested analysis is mainly founded on the Aristotelian concepts of ‘essence’ and ‘accident.’ Thus, the method is concerned with distinguish

This thesis presents investigations for the improvement of electrical contact and catalytical properties of two fungal redox enzymes, cellobiose dehydrogenase (CDH) and pyranose dehydrogenase (PDH), with electrodes and the use of the prepared electrodes as carbohydrate biosensors and in enzymatic biofuel cells. The performance of enzyme modified electrodes can be improved in two ways, by modifying

In order to understand the formation and evolution of the Galaxy it is imperative to know when different components formed. This means at the most basic level that we need to know the ages of stars. The present work demonstrates the many problems inherent in determining the ages of stars through comparison with stellar evolutionary models. Furthermore, solutions to some of these problems are prese

Popular Abstract in Swedish Enzymer är viktiga ämnen i naturen. Vi talar då och då om att vi förbränner vår mat. Trots detta känner vi oss oftast inte särskilt varma, i alla fall inte så att det bränns. Visst bränner vi vår mat. Socker omvandlas till koldioxid och vatten precis som om vi hade eldat upp det utanför kroppen. Skillnanden är att kroppen omvandlar sockret långsammare och mer kontrollerWith the goal to study the mechanisms of dinuclear metalloenzymes, a new line of synthetic and computational models were prepared and studied. Mixed imidazole and carboxylate multidentate complexes were synthesized to better simulate carboxylate-rich ligand environments. Of the compounds, which showed to be the most useful, were one symmetric and the other one asymmetric and in both cases they wer

Popular Abstract in Swedish I min avhandling har jag studerat marina sedimentkärnor från två kustområden i SE Sverige, dels från Gåsfjärden, strax söder om Västervik i Småland, och dels från kusten utanför Karlskrona i Blekinge. Med syftet att studera hur Östersjöns kustmiljö har förändrats sedan mitten av Holocen (~5000 år sedan). Resultaten visar att kustmiljön har påverkats av flera stressfaktoIn this thesis, I used two coastal sediment sequences from SE Sweden to study how Baltic Sea coastal environment has changed since the mid-Holocene. The results show the coastal environment has been influenced by multi-stressors, such as climate change, shoreline regression and anthropogenic activities. Using the sediment sequence from Karlskrona Bay, past coastal environment between 7300 and 350

Abstract in Danish Kapitlet sætter fokus på, hvordan sygeplejestuderende kan udvikle professionelle kompetencer i den kliniske del af sygeplejerskeuddannelsen. Indledningsvis reflekteres over kompetencebegrebet knyttet til professionsbacheloruddannelsen, og begrebet læring defineres som henholdsvis erhvervelse og deltagelse. Erhvervelse som læringstilgang er den mest dominerende forståelse af læri

Popular Abstract in Swedish Under de senaste två decennierna har transplantation av embryonal vävnad från ventrala mesencephalon, mitthjärnan, utvecklats till en möjlig terapi för Parkinson’s sjukdom. Ju bättre transplantatet återställer den dopaminerga neurotransmissionen, desto större blir den motoriska förbättringen hos patienten. Dessvärre dör över 90% av de dopaminerga nervcellerna under tranOver the past two decades, grafting of embryonic nigral tissue has developed into a feasible therapeutic strategy for Parkinson's disease (PD). It has become apparent that the degree of restoration of dopaminergic neurotransmission by the transplanted cells is highly correlated to the symptomatic relief. However, the efficacy of the treatment is still far from optimal: More than 90% of the grafted