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Associations between cerebral small vessel disease and reduced forced vital capacity and expiratory volume in a general healthy Swedish elder population study-Good Aging in Skåne

BackgroundCerebral small vessel disease (CSVD) is one of the most important causes of cognitive decline. Only a few previous studies have evaluated lung function measures in relation to brain neuropathological changes, and even less studies on specific lesions and areas that could shed light on mechanisms of CSVD.ObjectiveThe aim was to study the association between lung function and CSVD in the g

Communicating in the Face of Global Crises : Organization, Strategy, and ‘Doing the Right Thing’

Communicating in the Face of Global Crises explores the complex ways organizations and their strategic practices are communicatively constituted in relation to the ethical expectations of global publics.Positioning organizational strategies as communicative accomplishments, an international team of authors redirect attention to the important role of communication in constituting responses to globa

Establishing Reference Values for Pulse Wave Velocity in Young People

BACKGROUND: Aortic pulse wave velocity (PWV) is an indicator of vascular aging and has proven to be effective in adult cardiovascular risk assessment. To use it in young people to identify those who may be at increased cardiovascular disease risk, reference values need to be determined. The Youth Vascular Consortium is a large, international database which was established to investigate vascular a

Documentation of suicidality in connection with specialised healthcare for physical conditions : a retrospective review of somatic medical records prior to suicide in Sweden

OBJECTIVES: To evaluate whether suicidality was documented prior to suicide in patients in contact with specialised somatic healthcare providers for physical conditions and to identify factors related to such documentation.DESIGN AND SETTINGS: Retrospective cohort study in which medical records from specialised somatic (non-psychiatric) healthcare services (internal medicine, infectious disease, s

Impact of maternal prepregnancy body mass index on neonatal outcomes following extremely preterm birth

Objective: Extremes of prepregnancy maternal BMI increase neonatal mortality and morbidity at term. They also increase the risk of extremely preterm (EP, i.e., <27 weeks' gestational age) births. However, the association between maternal BMI and outcomes for EP babies is poorly understood. Methods: We used a cross-country design, bringing together the following three population-based, prospective,

FROM TRUST TO TRUSTWORTHINESS : Formalising consumer behaviour with discourse on Airbnb platform

One of the most important consumers’ needs in their decision-making process is reduction of risks. On online platforms, trust is the most powerful tool for mitigating risks in making consumption decisions, especially in relation to tourism services that customers are unable to experience before the trip. In the digital age, trust is often mediated by information and communication technologies (ICT

Multimorbidity, comorbidity, frailty, and venous thromboembolism

Multimorbidity, i.e., the presence of two or more long-term health conditions, is challenging for healthcare systems worldwide. A related term is comorbidity. This denotes any condition that has existed or may occur during the clinical course of a patient who has the index disease under study. Moreover, frailty is also inter-related with multimorbidity but represents a distinct clinical concept. F

Anywhere workers and the sustainable development of tourist destinations

Working from anywhere, often associated with digital nomadism, is a growing trend that blurs the boundaries between work and leisure, with individuals choosing to work from tourist destinations. The phenomenon has caught the attention of academics, who mainly focus on the lifestyle aspects of digital nomadism. However, destination management organizations, as well as the tourism and hospitality in

Use of common cardiovascular disease drugs and risk of dementia : A case–control study in Swedish national register data

INTRODUCTION: Cardiovascular drug use may help prevent dementia; however, current evidence is mixed. Using a case–control design, we investigated the association between duration and combination of multiple cardiovascular drug classes and incident dementia. METHODS: From the Swedish national registers, we included 88,065 incident dementia cases aged ≥ 70 at diagnosis between 2011 and 2016 and 880,

Effectiveness of JAK Inhibitors Compared With Biologic Disease-Modifying Antirheumatic Drugs on Pain Reduction in Rheumatoid Arthritis : Results From a Nationwide Swedish Cohort Study

Objective: To compare the effectiveness of JAK inhibitors (JAKis) and biologic disease-modifying antirheumatic drugs (bDMARDs) on pain in patients with rheumatoid arthritis. Methods: In this retrospective study, we investigated patients with a diagnosis of rheumatoid arthritis, starting treatment with a JAKi (n = 1,827), a tumor necrosis factor inhibitor (TNFi; n = 6,422), an interleukin-6 inhibit

Association between exposure to pyrethroids and chlorpyrifos at age 5 years and IQ at age 7 years among children from the Odense Child Cohort, a prospective birth cohort study

Background: Over the past decade, the use of organophosphate insecticides including chlorpyrifos has faced increasing restrictions due to health concerns, leading to a rise in use of pyrethroids. Concerns about neurodevelopmental insults following pyrethroids exposure exist, but few studies have examined the long-term effects of childhood exposure to chlorpyrifos and pyrethroids on IQ. Objective:

Prediction of stroke severity : systematic evaluation of lesion representations

Objective: To systematically evaluate which lesion-based imaging features and methods allow for the best statistical prediction of poststroke deficits across independent datasets. Methods: We utilized imaging and clinical data from three independent datasets of patients experiencing acute stroke (N1 = 109, N2 = 638, N3 = 794) to statistically predict acute stroke severity (NIHSS) based on lesion v

“A feeling of being part of the future” : a qualitative study on physical therapists’ experiences of delivering digital first-line treatment for hip and knee osteoarthritis

Introduction: Digital options for osteoarthritis (OA) treatment are increasingly available with high patient satisfaction and acceptability. Little is, however, known about physical therapists’ (PT) perception of this treatment modality. Objective: To investigate PT’s experience of delivering digital treatment for hip and knee OA using a smart-phone application. Method: Nine PTs (mean age 36 years

Eutrophication promotes resource use efficiency and toxin production of Microcystis in a future climate warming scenario

Addressing the risks of cyanobacterial blooms and toxin production under ongoing and accelerating eutrophication and climate warming is crucial for both water ecosystem services and human health. Therefore, we here explored the interactive effects of eutrophication and warming on freshwater ecosystems, focusing on Microcystis and its cyanotoxin production. We employed a large-scale mesocosm system