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A distinctive profile of family genetic risk scores in a Swedish national sample of cases of fibromyalgia, irritable bowel syndrome, and chronic fatigue syndrome compared to rheumatoid arthritis and major depression

Background Functional somatic disorders (FSD) feature medical symptoms of unclear etiology. Attempts to clarify their origin have been hampered by a lack of rigorous research designs. We sought to clarify the etiology of the FSD by examining the genetic risk patterns for FSD and other related disorders. Methods This study was performed in 5 829 186 individuals from Swedish national registers. We q

High turnover photocatalytic hydrogen formation with an Fe(iii) N-heterocyclic carbene photosensitiser

Herein we report the first high turnover photocatalytic hydrogen formation reaction based on an earth-abundant FeIII-NHC photosensitiser. The reaction occurs via reductive quenching of the 2LMCT excited state that can be directly excited with green light and employs either Pt-colloids or [Co(dmgH)2pyCl] as proton reduction catalysts and [HNEt3][BF4] and triethanolamine/triethylamine as proton and

How older adults relate to their own voices : a qualitative study of subjective experiences of the aging voice

Aim: The aim of this study was to investigate how otherwise healthy older adults with self-assessed voice problems relate to their voice and voice changes. Method: Focus groups were conducted at an activity center to identify how older adults reflect on their own voice and the aging voice in general. The interviews were audio recorded and transcribed. The analysis was done using thematic content a

Order and disorder in the modulated phase hp-Mg9Ge5.1

Single crystals of Mg9Ge5.1(2) were obtained at a pressure of 5 GPa in the temperature range 723 to 1273 K. The metastable high-pressure phase exhibits a crystal structure, which may be described as a host-guest variety of an UCl3-type framework. The atomic arrangement is characterized by a host crystal structure Mg9Ge3 with disordered germanium guests (≈2 Ge per formula unit) in the channels. The

Mechanochemical synthesis of stable, quantum-confined CsPbBr3perovskite nanocrystals with blue-green emission and high PLQY

Cesium lead halides are a family of bright, visible-light emitting materials with near-unity photoluminescence quantum yield (PLQY) in nanocrystals (NCs). The usual way to achieve visible light-emission tunability is by mixing halides, which often leads to phase separation and poor stability. While the NCs should also show size-dependent PL emission, reports on strong quantum confinement in these

Participation in exercise-based cardiac rehabilitation is related to reduced total mortality in both men and women : Results from the SWEDEHEART registry

Aims: Participation in exercise-based cardiac rehabilitation (exCR) increases aerobic capacity and improves outcomes in patients following myocardial infarction (MI) and is therefore universally recommended. While meta-Analyses consistently report that participation in exCR reduces cardiovascular mortality, there are conflicting results regarding effects on total mortality. Presently, many eligibl

Reproductive hormone levels, androgen receptor CAG repeat length and their longitudinal relationships with decline in cognitive subdomains in men : The European Male Ageing Study.

Objective: It has been proposed that endogenous sex hormone levels may present a modifiable risk factor for cognitive decline. However, the evidence for effects of sex steroids on cognitive ageing is conflicting. We therefore investigated associations between endogenous hormone levels, androgen receptor CAG repeat length, and cognitive domains including visuoconstructional abilities, visual memory

Atomic Structure and Valence State of Cobalt Nanocrystals on Carbon under Syngas Versus Hydrogen Reduction

The composition of the reducing gas in the activation of Co Fischer-Tropsch synthesis catalysts determines the nature of the catalytically active Co species. This study reports on the effect of H2versus syngas (H2/CO = 2) on the reducibility of Co3O4nanoparticles supported on hollow carbon spheres, using ex situ and in situ high-resolution aberration-corrected analytical electron microscopy. High-

Gene-environment interactions and metal toxicity

Humans are exposed to various metals through many different routes and each person’s genetic background contributes to their susceptibility to metal toxicity. In addition, recent evidence points to a role for the genetics of the human microbiome in metal uptake and toxicity. DNA sequence variation in genes that regulate metal toxicokinetics and toxicodynamics influences metal accumulation and rete

Trust in the healthcare system and mortality : A population-based prospective cohort study in southern Sweden

Aims: To investigate associations between trust in the healthcare system and all-cause, cardiovascular, cancer and other causes mortality. Study design: Prospective cohort study. Methods: A public health questionnaire was conducted in 2008 in Scania, the southernmost part of Sweden, with a 54.1% participation rate with a postal questionnaire and three reminders. In this study 24,833 respondents we

Robust topological superconductivity in weakly coupled nanowire-superconductor hybrid structures

We investigate the role of the coupling between a spin-orbit coupled semiconductor nanowire and a conventional s-wave superconductor on the emergence of the topological superconducting phase with Majorana bound states in an applied magnetic field. We show that when the coupling is strong, the topological phase transition point is very sensitive to the size of the superconductor and in order to rea

Cold sensitivity and its association to functional disability following a major nerve trunk injury in the upper extremity—A national registry-based study

Aims To investigate self-reported cold sensitivity and functional disability after a repaired major nerve trunk injury in the upper extremity. Methods We identified 735 individuals with a major nerve trunk injury in the upper extremity, surgically treated with direct nerve repair or reconstructed with nerve autografts, in the Swedish national quality registry for hand surgery (HAKIR). Patient-repo

Growth and Characterization of Core-Branch Nanowire Structures

This thesis investigates growth of III – V semiconductor nanowire (NW) arrays, in a core- branch architecture, with the aim to develop diffusion driven light emitting diodes (LED) on NWs. Diffusion driven LEDs are based on the concept of decoupling the active region from the p-n junction. The carriers are injected by diffusion in the active region, because of the bandgap difference between the pn

Role of multiple risk factors in mental disorders diagnosed in middle-aged women : A population-based follow-up study

The aims of the study were 1). to investigate the association between the potential risk factors including socio-demographic, lifestyle and DNA methylation and mental disorders in middle-aged women from a large population-based follow-up study, and 2). to estimate the risk score by combining the potential risk factors to examine the mental disorder's incidence. A total of 6461 women, aged 50-65 ye

Junction Engineering in Nanostructured Optoelectronic Devices

Semiconductor nanowires have proven to be promising building blocks for next-generation optoelectronic devices. The nanometric dimensions of nanowires provides strain relaxation capability, thus enabling the heteroepitaxy of III-V materials on silicon, as well as providing the possibility of realizing optoelectronic devices with lattice-mismatched material combinations. The subwavelength dimension

Initial intraocular pressure reduction by mono- versus multi-therapy in patients with open-angle glaucoma : results from the Glaucoma Intensive Treatment Study

PURPOSE: To study newly diagnosed glaucoma patients given mono- or multi-therapy regarding differences in initial intraocular pressure (IOP) reduction, target IOP levels reached and influence of untreated baseline IOP on IOP reduction.METHODS: Patients newly diagnosed with manifest primary open-angle glaucoma and included in the Glaucoma Intensive Treatment Study (GITS) were randomized to immediat

Social capital in epidemiology

Inspired by Putnam’s study of Italy, this chapter develops applications that test the issue of social capital and health in the context of social epidemiology. Three central concepts are explained. The chapter attends to the technical issues, including, for example, the portion of children in subgroups identifying conflicts. The author then comes to his main message: the value of longitudinal expe