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Genetically Determined Risk of Depression and Functional Outcome After Ischemic Stroke

Background and Purpose- Psychosocial factors can have implications for ischemic stroke risk and recovery. This study investigated the effect of genetically determined risk of depression on these outcomes using the Mendelian randomization (MR) framework. Methods- Genetic instruments for risk of depression were identified in a discovery genome-wide association study of 246 363 cases and 561 190 cont

Sequence of 305,996 total hip and knee arthroplasties in patients undergoing operations on more than 1 joint

Background and purpose — Patient-specific data on multiple total arthroplasties (TA) of the lower limbs due to osteoarthritis (OA) are limited. We investigated the sequence of surgical procedures and risk factors for additional surgery in such patients. Patients and methods — 305,996 patients operated with a TA of the hip and/or knee due to OA were extracted from the Swedish National Hip (SHAR) an

Potential pitfalls of the early-time dynamics in two-dimensional electronic spectroscopy

Two-dimensional electronic spectroscopy, and especially the polarization-controlled version of it, is the cutting edge technique for disentangling various types of coherences in molecules and molecular aggregates. In order to evaluate the electronic coherences, which often decay on a 100 fs time scale, the early population times have to be included in the analysis. However, signals in this region

Validation of Lithuanian Arthroplasty Register Telephone Survey of 2769 Patients Operated for Total Knee Replacement

Background and objectives: The aim of our study is to validate the registration of knee arthroplasty revisions in the Lithuanian Arthroplasty Register (LAR) and thus give an indication of the accuracy of the published revision rates. Materials and methods: A total of 4269 primary total knee arthroplasties (TKAs) registered in the LAR between 2013 and 2015 were included. Two years after surgery the

Thermal performance enhancement in a wedge duct with in-line pin fins combined with vortex generators

Purpose: The purpose of this paper is to enhance the heat transfer and thermal performance in the trailing edge region of the vane with vortex generators (VGs). Design/methodology/approach: This numerical study presents the enhancement of thermal performance in the trailing part of a gas turbine blade. In the trailing part, generally, pin fins are used either in staggered or in-line arrangements t

Using fluorescence detected two-dimensional spectroscopy to investigate initial exciton delocalization between coupled chromophores

Förster theory describes electronic exciton energy migration in molecular assemblies as an incoherent hopping process between donor and acceptor molecules. The rate is expressed in terms of the overlap integral between donor fluorescence and acceptor absorption spectra. Typical time scales for systems like photosynthetic antennae are on the order of a few picoseconds. Prior to transfer, it is assu

High Resolution Mapping of Two-Photon Excited Photocurrent in Perovskite Microplate Photodetector

We fabricate photodetectors based on solution-processed single CH3NH3PbBr3 microcrystals (MCs) and map the two-photon absorption (TPA) excited photocurrent (PC) with spatial resolution of 1 μm. We find that the charge carrier transport length in the MCs depends on the applied electric field, and increases from 5.7 μm for 0.02 V bias (dominated by carrier diffusion) to 23.2 μm for 2 V bias (dominat

Combining synchrotron light with laser technology in catalysis research

High-energy surface X-ray diffraction (HESXRD) provides surface structural information with high temporal resolution, facilitating the understanding of the surface dynamics and structure of the active phase of catalytic surfaces. The surface structure detected during the reaction is sensitive to the composition of the gas phase close to the catalyst surface, and the catalytic activity of the sampl

Predicting undetected glaucoma according to age and IOP : a prediction model developed from a primarily European-derived population

Purpose: To model prediction of undetected glaucoma in a predominantly white population, based on intraocular pressure (IOP) and subject age. Methods: In 1992–1997, a population screening for glaucoma was performed at Malmö University Hospital where individuals between 55–79 years of age (n = 46 614) living in Malmö, were invited to a free eye health examination. Recently examined patients were no

Socioeconomic differences in body mass index in Spain: An intersectional multilevel analysis of individual heterogeneity and discriminatory accuracy

Many studies have demonstrated the existence of simple, unidimensional socioeconomic gradients in body mass index (BMI). However, in the present paper we move beyond such traditional analyses by simultaneously considering multiple demographic and socioeconomic dimensions. Using the Spanish National Health Survey 2011–2012, we apply intersectionality theory and multilevel analysis of individual het

A New SITA Perimetric Threshold Testing Algorithm : Construction and a Multicenter Clinical Study

Purpose: To describe a new time-saving threshold visual field–testing strategy—Swedish Interactive Thresholding Algorithm (SITA) Faster, which is intended to replace SITA Fast—and to report on a clinical evaluation of this new strategy. Design: Description and validity analysis for modifications applied to SITA Fast. Methods: Five centers tested 1 eye of each of 126 glaucoma and glaucoma suspect p

Double-crossed polarization transient grating for distinction and characterization of coherences

Coherent phenomena have been widely suggested to play a role in efficient photosynthetic light harvesting and charge separation processes. To substantiate these ideas, separation of intramolecular vibrational coherences from purely electronic or mixed vibronic coherences is essential. To this end, polarization-controlled two-dimensional electronic spectroscopy has been shown to provide an effectiv

Luminescent Intermediates and Humidity-Dependent Room-Temperature Conversion of the MAPbI3 Perovskite Precursor

Preparation of metal-halide perovskites under room temperature attracts attention because of energy saving by removing thermal annealing. Room-temperature transformation of spin-cast wet films consisting of methylammonium (MA) iodide, PbI2, and dimethylformamide toward solid MAPbI3 perovskite proceeds via several intermediate crystalline states and is strongly dependent on ambient humidity. Light

Nanoscale quantum calorimetry with electronic temperature fluctuations

Motivated by the recent development of fast and ultrasensitive thermometry in nanoscale systems, we investigate quantum calorimetric detection of individual heat pulses in the sub-meV energy range. We propose a hybrid superconducting injector-calorimeter setup, with the energy of injected pulses carried by tunneling electrons. It is shown that the superconductor constitutes a versatile injector, w

A new look at effective interactions between microgel particles

Thermoresponsive microgels find widespread use as colloidal model systems, because their temperature-dependent size allows facile tuning of their volume fraction in situ. However, an interaction potential unifying their behavior across the entire phase diagram is sorely lacking. Here we investigate microgel suspensions in the fluid regime at different volume fractions and temperatures, and in the

Overuse of methylphenidate : an analysis of Swedish pharmacy dispensing data

Purpose: To identify overuse of methylphenidate and to investigate patterns of overuse in relation to sociodemographic and clinical characteristics.Patients and methods: Swedish national, pharmacy dispensing data were analyzed for all 56,922 individuals aged 6-79 years, who filled a methylphenidate prescription between 2010 and 2011. Overuse was defined as having above 150% days covered by the dis

Temperature characterization of an operando flow reactor for heterogeneous catalysis

In this work, we present several methods to determine the temperature of a catalyst sample, as well as the gas surrounding it, in a typical flow reactor used for operando research on heterogeneous catalysis. To determine the sample temperature, we present an approach using calibrated IR-camera imagery, as well as thermographic phosphors. For the gas temperature, we present methods to extract tempe

Red-Shifted Photoluminescence from Crystal Edges Due to Carrier Redistribution and Reabsorption in Lead Triiodide Perovskites

Photoluminescence (PL) of CH 3 NH 3 PbI 3 perovskites depends strongly on sample preparation, atmosphere, crystal size, and so forth. However, the origin of these dependencies is always misunderstood because of the co-works of many different factors. Herein, we prepared hexagonal-shaped single crystals with tens of micrometers in size and observed a red-shifted PL emission (800-830 nm) mainly

Two-photon excitation spectroscopy of 1,5–Diphenyl-1,3,5-hexatriene using phase modulation

We have used two-photon Fourier transform spectroscopy to investigate the first singlet excited state (S1) of a prototypical polyene molecule 1,5—Diphenyl-1,3,5-hexatriene. As the S1 state in the polyenes is a one-photon forbidden transition, the structure of its vibrational levels cannot be studied using resonant linear excitation. Although this level is accessible with two-photon excitation, pre