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Although elevated blood or sputum eosinophils are present in many patients with chronic obstructive pulmonary disease (COPD), uncertainties remain regarding the anatomical distribution pattern of lung-infiltrating eosinophils. Basophils have remained virtually unexplored in COPD. This study mapped tissue-infiltrating eosinophils, basophils, and eosinophil-promoting immune mechanisms in COPD-affect

Background: Although alcohol use disorder (AUD) runs strongly within families, studies examining the impact of rearing environment, unconfounded by genetic effects, are rare and, to date, contradictory. We here seek to conduct such a study using an adoptive co-sib control design. Methods: Defining high-risk as having 3/41 biological parent with an externalizing syndrome (AUD, drug abuse or crime),

Background: Drug abuse is frequently associated with negative sequelae such as reduced socioeconomic functioning. The extent to which these associations are attributable to a causal role of the disorder versus confounding factors that increase risk for both drug abuse and negative socioeconomic outcomes is unclear. Methods: Drug abuse cases were identified using Swedish national medical, pharmacy,

Aim: To compare incidence of urolithiasis in second-generation immigrant children aged 0-17 years to children of Swedish-born parents. Methods: A nationwide study of individuals residing in Sweden. Urolithiasis was defined as having at least one registered diagnosis of urolithiasis in the Swedish National Patient Register between January 1, 1998 and December 31, 2015. Cox regression analysis was u

Superconductor-ferromagnetic heterostructures have been suggested as one of the most promising alternatives of realizing odd-frequency superconductivity. In this work we consider the limit of shrinking the ferromagnetic region to the limit of a single impurity embedded in a conventional superconductor, which gives rise to localized Yu-Shiba-Rusinov (YSR) bound states with energies inside the super

The laws of thermodynamics allow work extraction from a single heat bath provided that the entropy decrease of the bath is compensated for by another part of the system. We propose a thermodynamic quantum engine that exploits this principle and consists of two electrons on a double quantum dot (QD). The engine is fueled by providing it with singlet spin states, where the electron spins on differen

In this work, we demonstrate a vertical processing method to fabricate nanowire (NW)-based devices. This method combines the strong light absorption ability caused by the NW geometry and exposure to dose-dependent clearance properties of a photo-sensitive polymer. By embedding NW arrays in a polymer, the NW light absorption leads to self-limited exposure and selective removal of the polymer. This

In this article, the concept of the employer is analysed for Swedish conditions from a variety of perspectives. The special difficulties that face the private sector are charted, as are the principles of the legal subject in triparty contracts with temporary employment agencies, platform work, and umbrella companies. Found to go hand in hand with the concept of employee, the concept of the employe

BACKGROUND: Serial assessment of phosphorus is currently recommended by the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines, but its additional value versus a single measurement is uncertain. METHODS: We studied data from 17 414 HD patients in the Dialysis Outcomes and Practice Patterns Study, a prospective cohort study, and calculated the area under the curve (AUC) by multiplying the

Autoimmune hepatitis (AH) and primary biliary cirrhosis (PBC) are autoimmune diseases (AIDs) targeting cellular components of the liver. Being rare diseases, limited data are available about familial risks among these AIDs (concordant) or between them and other AIDs (discordant). We aimed to carry out an unbiased study on these AIDs based on medically diagnosed patients. We collected data on patie

Circulating cell-free nuclear DNA (nDNA) has been implicated in individual cancer types with a diagnostic value; however, the role of cell-free mitochondrial DNA (mtDNA) in cancers is controversial. We aimed to investigate and compare the diagnostic potential of both nDNA and mtDNA for multiple cancers and to investigate their ability to distinguish multiple cancers from healthy controls and from

We present spatially and spectrally resolved emission from nanowires with a thin radial layer of GaAs embedded in AlGaAs barriers, grown radially around taper-free GaAs cores. The GaAs layers are thin enough to show quantization, and are quantum wells. Due to their shape, they are referred to as quantum well tubes (QWTs). We have investigated three different nominal QWT thicknesses: 1.5, 2.0, and

Single crystals of Fe0.43Mo2.56SbO9.5 were obtained by hydrothermal techniques at 230◦C. The crystal structure was determined from single crystal X-ray diffraction data. The compound crystallizes in the non-centrosymmetric space group Pc with unit cell parameters a = 4.0003(2) Å, b = 7.3355(3) Å, c = 12.6985(6) Å, β = 90◦. The crystal structure comprises five crystallographically independent M ato

It is predicted that novel nanometer-sized structures incorporating nanoparticles will have a considerable impact on our lives during the coming decades. Engineered nanoparticles are already found in a number of commercially available products. However, many applications of these nanoparticles have only reached the stage of promising ideas or research demonstrations. The number of nanoparticle-bas