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Plasma circulating cell-free mitochondrial DNA in depressive disorders

Plasma circulating cell-free mitochondrial DNA (ccf-mtDNA) is an immunogenic molecule and a novel biomarker of psychiatric disorders. Some previous studies reported increased levels of ccf-mtDNA in unmedicated depression and recent suicide attempters, while other studies found unchanged or decreased ccf-mtDNA levels in depression. Inconsistent findings across studies may be explained by small samp

Implementing an intermittent spin-coating strategy to enable bottom-up crystallization in layered halide perovskites

Two-dimensional halide perovskites (2D PVSKs) have drawn tremendous attentions owing to their outstanding ambient stability. However, the random orientation of layered crystals severely impedes the out-of-plane carrier transport and limits the solar cell performance. An in-depth understanding coupled with an effective control of the crystallization in 2D PVSKs is the crux for highly efficient and

Single-cell measurements of two-dimensional binding affinity across cell contacts

The two-dimensional (2D) affinity between protein molecules across contacting cells is a key parameter regulating and initiating several cellular processes. However, measuring 2D affinity can be challenging, and experimental data are limited. In addition, the obtained 2D affinities are typically averaged over the cell population. We here present a method to measure 2D affinity on single cells bind

First experiments with a water-jet plasma X-ray source driven by the novel high-power-high-repetition rate L1 Allegra laser at ELI Beamlines

ELI Beamlines is a rapidly progressing pillar of the pan-European Extreme Light Infrastructure (ELI) project focusing on the development and deployment of science driven by high-power lasers for user operations. This work reports the results of a commissioning run of a water-jet plasma X-ray source driven by the L1 Allegra laser, outlining the current capabilities and future potential of the syste

Lateral III-V Nanowire MOSFETs in Low-Noise Amplifier Stages

Lateral III-V nanowire (NW) MOSFETs are a promising candidate for high-frequency electronics. However, their circuit performance is not yet assessed. Here, we integrate lateral nanowires (LNWs) in a circuit environment and characterize the transistors and amplifiers. MOSFETs are fabricated in a simple scheme with a dc transconductance of up to 1.3 mS/μm, ON-resistance down to 265 &#

False Positive Responses in Standard Automated Perimetry

Purpose: To analyze the relationship between rates of false positive (FP) responses and standard automated perimetry results. Design: Prospective multicenter cross-sectional study. Methods: One hundred twenty-six patients with manifest or suspect glaucoma were tested with Swedish Interactive Thresholding Algorithm (SITA) Standard, SITA Fast, and SITA Faster at each of 2 visits. We calculated inter

Social capital, the miniaturization of community, traditionalism and mortality : A population-based prospective cohort study in southern Sweden

Objectives: To investigate associations between social capital, miniaturization of community and traditionalism and all-cause, cardiovascular (CVD), cancer and other causes mortality. Study design: Prospective cohort study. Methods: The 2008 public health survey in Scania in the southernmost part of Sweden was conducted with a postal questionnaire posted to a stratified random sample aged 18–80. T

A method for estimating defects in ferroelectric thin film MOSCAPs

We propose a capacitance measurement scheme that enables quantitative characterization of ferroelectric thin films integrated onsemiconductors. The film defect density is estimated by measurements of the CV hysteresis and frequency dispersion, whereas importantdevice parameters such as memory window and endurance can be extracted by a unidirectional CV method. The simple measurementscheme and the

New distributional, biological and taxonomic information on the genus Eulophinusia Girault (Hymenoptera : Eulophidae)

The genus Eulophinusia Girault (Hymenoptera: Eulophidae), previously known from Australia and India, is newly recorded from the Americas (Canada, Costa Rica, Dominican Republic). The morphological diagnosis of the genus is enhanced through the discovery of an unnoticed and unique feature - an intricate jigsaw-like microsculptural pattern on the mesoscutellum. The new species described here, Euloph

Association of clinically relevant carpal tunnel syndrome with type of work and level of education : a general-population study

Carpal tunnel syndrome (CTS) is a common cause of work disability. The association with occupational load and education level has not been established in general-population studies. The purpose of this study was to investigate the association of clinically relevant CTS with work and education. From the Healthcare Register of Skane region (population 1.2 million) in southern Sweden we identified al

My memories of ahmed zewail - from a snowy northern Sweden to the nobel prize

In the summer of 1993, two Russian scientists from the Institute of Physics in Nizhny Novgorod drove the 1, 934 km to Umeå, where I was based at that time, in their red Lada car loaded with a home-built Ti:Sa laser. Within a few days, the laser was put in operation, pumped by a small argon-ion laser, and produced stable -100 fs pulses at 790 nm. These pulses were applied to our favorite topic at t

Revisiting Optical Reflectance from Au(111) Electrode Surfaces with Combined High-Energy Surface X-ray Diffraction

We have combined high-energy surface X-ray diffraction (HESXRD) with 2D surface optical reflectance (2D-SOR) to perform in situ electrochemical measurements of a Au(111) electrode in 0.1 M HClO4 electrolyte. We show that electrochemically induced changes to Au(111) surface during cyclic voltammetry can be simultaneously observed with 2D-SOR and HESXRD. We discuss how small one atom high 1x1 island

Reduced Carbon Monoxide Saturation Coverage on Vicinal Palladium Surfaces : The Importance of the Adsorption Site

Steps at metal surfaces may influence energetics and kinetics of catalytic reactions in unexpected ways. Here, we report a significant reduction of the CO saturation coverage in Pd vicinal surfaces, which in turn is relevant for the light-off of the CO oxidation reaction. The study is based on a systematic investigation of CO adsorption on vicinal Pd(111) surfaces making use of a curved Pd crystal

Presence of Maximal Characteristic Time in Photoluminescence Blinking of MAPbI3 Perovskite

Photoluminescence (PL) blinking is a common phenomenon in nanostructured semiconductors associated with charge trapping and defect dynamics. PL blinking kinetics exhibit very broadly distributed timescales. The traditionally employed analysis of probability distribution of ON and OFF events suffers from ambiguities in their determination in complex PL traces making its suitability questionable. He

Envisioning a resilient future for biodiversity conservation in the wake of the COVID-19 pandemic

As the COVID-19 pandemic continues to affect societies across the world, the ongoing economic and social disruptions are likely to present fundamental challenges for current and future biodiversity conservation. We review the literature for outcomes of past major societal, political, economic and zoonotic perturbations on biodiversity conservation, and demonstrate the complex implications of pertu

Population heterogeneity in associations between hormonal contraception and antidepressant use in Sweden : a prospective cohort study applying intersectional multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA)

OBJECTIVES: From a reproductive justice framework, we aimed to investigate how a possible association between hormonal contraceptive (HC) and antidepressants use (as a proxy for depression) is distributed across intersectional strata in the population. We aimed to visualise how intersecting power dynamics may operate in combination with HC use to increase or decrease subsequent use of antidepressa

A high-repetition rate attosecond pulse source for coincidence spectroscopy

The power of attosecond pump-probe spectroscopy combined with advanced detection schemes, such as photoelectron/ion coincidence spectrometers and time-resolved photoelectron emission microscopy (PEEM), can be unleashed by properly accounting for the repetition rate of the source. In this work, we present a high-repetition rate (200 kHz) attosecond pulse source that opens up for exploring phenomena

Directed Self-Assembly of Polarizable Ellipsoids in an External Electric Field

The interplay between shape anisotropy and directed long-range interactions enables the self-assembly of complex colloidal structures. As a recent highlight, ellipsoidal particles polarized in an external electric field were observed to associate into well-defined tubular structures. In this study, we systematically investigate such directed self-assembly using Monte Carlo simulations of a two-poi

Jamming and overpacking fuzzy microgels: Deformation, interpenetration, and compression

Tuning the solubility of fuzzy polymer microgels by external triggers, such as temperature or pH, provides a unique mechanism for controlling the porosity and size of colloidal particles on the nanoscale. As a consequence, these smart microgel particles are being considered for applications ranging from viscosity modifiers and sensing to drug delivery and as models for the glass and the jamming tr

Sociodemographic patterns in pharmacy dispensing of medications for erectile dysfunction in Sweden

PURPOSE: The purpose of this study is to investigate the relationship between sociodemographic factors and pharmacy dispensing of medications for erectile dysfunction (ED) in the general population of middle-aged and elderly men. By considering a number of medical conditions that could promote or contraindicate use of ED medication, the analysis could help capture prescription patterns that might