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BACKGROUND: Previously, small studies have found that BRCA1 and BRCA2 breast tumors differ in their pathology. Analysis of larger datasets of mutation carriers should allow further tumor characterization.METHODS: We used data from 4,325 BRCA1 and 2,568 BRCA2 mutation carriers to analyze the pathology of invasive breast, ovarian, and contralateral breast cancers.RESULTS: There was strong evidence t

Information technology is a vital driver in today’s business environment. Recent developments of IT have facilitated for the relatively easy creation of markets on the Internet, so called B2B-marketplaces. However, judging from the survival rate of B2B-marketplaces (5 to 10 per cent), it seems like B2B-marketplaces are doing something wrong. This paper scrutinises several theoretical frameworks re

Trafikbullers inverkan på sömnen har undersökts medelst EEG-, EOG- och EMG-registreringar på sju unga män (21-27 år) och sex äldre män (63-74 år) i deras vanliga hemmiljö längs hårt trafikerade vägar (trafikintensitet cirka 450 fordonspassager med toppbullernivå överstigande 40 dB (A) per natt). Effekten av dämpning (cirka 10 dB (A)) av inomhusbullret genom montering av ljudisolerande plattor i fö

Although the research on the design of heterogeneous concurrent systems has a long and rich history, a unified design methodology and tool support have not emerged so far. Therefore, the creation of such systems remains a difficult, time-consuming and error-prone process. The absence of principled support for system evaluation and optimization at high level of abstraction makes the quality of the

Fields of Green and Gold är en multipel fallstudie som analyserar placeringen och etableringen av två storskaliga, berömda och påkostade golfanläggningar för att därigenom undersöka den exklusiva golfens politiska ekologi. De fall som studeras är Bro Hof Slott Golf Club i Upplands-Bro - som öppnade 2007 - och Trump International Golf Links Scotland i Aberdeenshire - som öppnade 2012. Att analyseraFields of Green and Gold is a multiple case study analysing the placing and establishment of two large-scale, high-profile, upmarket golf developments with the aim of exploring a political ecology of high-end golf. The cases studied are Bro Hof Slott Golf Club in Upplands-Bro, opened in 2007, and Trump International Golf Links Scotland in Aberdeenshire, opened in 2012. Reading these two cases toge

The concept of Extended Producer Responsibility (EPR) has been underpining recycling/waste/product policy of a number of countries over the past two decades. However, it is considered that the understanding of the concept varies. This presents the findings from a survey conducted in Japan in 2013 to find out the actual perceptions of various stakeholders in Japan. It is part of a global survey con

Analys av Högsta domstolens beslut 2025-03-28, mål Ö 438-24 "Regionens medgivande

The lifelong risk of stroke following adverse pregnancy outcomes, and potential causality, are unknown. This study examined five major adverse pregnancy outcomes and long-term risk of stroke in a large population-based cohort. Methods A national cohort study was conducted of all 2 201 393 women with a singleton delivery in Sweden during 1973–2015, followed up for stroke through 2018. Cox regressio

Syftet med uppsatsen är att undersöka hur employer branding kan fungera som ett verktyg i syfte att attrahera IT-studenter som ska bli framtida unga IT-talanger. Detta kommer att besvaras med hjälp av fallstudie på ett svenskt IT-företag, i uppsatsen kommer vi att anta ett företagsperspektiv. Genom dokumentstudier och fyra stycken semistrukturerade intervjuer med anställda på IKEA IT har vi utvec

This article examines the novel and film, Balzac et la petite tailleuse chinoise, by the Franco-Chinese writer and filmmaker Dai Sijie, the story of which takes place against the background of the Cultural Revolution. The first part of my analysis will make clear how the film illuminates and dramatizes the special texture, aesthetic, and structure of the novel. I then move on to investigate the li

BACKGROUND:: There is a lack of knowledge about how the provision and availability of specialized palliative care relates to the quality of dying in hospital and community-based settings. AIM:: We aimed to explore the quality of care during last week of life in relation to different levels of palliative care development. DESIGN:: We investigated access to palliative care in Southern Sweden, where