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Rektalcancer är en sjukdom där behandlingsresultaten förbättrats kraftigt de senaste decennierna. Behandling för ändtarmscancer sker med antingen endast kirurgi eller kirurgi i kombination med onkologisk neoadjuvant behandling. Kirurgisk radikalitet, mikroskopisk marginal mellan tumörvävnad och frisk vävnad, är av stor betydelse för att minska risken för lokalrecidiv och öka överlevnaden
The development of Swedish linguistics during the 20th century reflects international development. The century started with focus on language history described according to the theory of sound laws. It is reasonable to call the period around the turn of the century the Golden Age of Nordic philology; characterized by the work of Adolf Noreen; Axel Kock and Elof Hellquist who clarified the basic de
Mediatisation is one of the central concepts by which to understand how the intensifying media and communications environment constructs our social world. The aim of research is to examine the conditions of sustainability communication in a media economy of visibility and recognition. To this end, we focus on how the phenomenon overtourism is constructed as a social sustainability challenge in new
Spontaneous intracerebral hemorrhage (ICH) is the most devastating form of stroke. To refine treatments, improved understanding of the secondary injury processes is needed. We compared energy metabolic, amyloid and neuroaxonal injury biomarkers in extracellular fluid (ECF) from the perihemorrhagic zone (PHZ) and non-injured (NCX) brain tissue, cerebrospinal fluid (CSF) and plasma. Patients (n = 11
This review highlights the importance of air quality in the African urban development process. We address connections between air pollution and (a) rapid urbanization, (b) social problems, (c) health impacts, (d) climate change, (e) policies, and ( f ) new innovations. We acknowledge that air pollution levels in Africa can be extremely high and a serious health threat. The toxic content of the pol
Contemporary ghost stories can be mediated through television series that familiarize viewers with the idea of supernatural/spiritual phenomena, and present a way of witnessing, experiencing and dealing with such phenomena. TheSwedish TV series Det Okända(The Unknown) is an example of such a production. A –presumably –spiritual phenomenon is tailored to fit a popular culture format and is served t
Multiple myeloma (MM) is the second most common blood malignancy, with several lines of evidence supporting an inherited genetic component. Here, we sequenced 177 affected individuals from 128 families, and 170 early-onset MM cases diagnosed before 55 years of age. Samples were identified and collected through nationwide efforts in France, Sweden, and Greece. We focused on rare germline protein tr
We explore the challenges facing the current academic training of economists in small European countries such as Sweden. The monolithic focus on publishing in the top-five journals, which prioritizes methodological rigor over problem-driven research, is often a threat to social relevance and policy applicability. This limits pluralism, excludes many talented economists, and fails to prepare gradua
I artikeln presenterar forskarna Tillsammans-projektet, som syftar till att förbättra socialt stöd genom samverkan mellan civilsamhället och vården. Projektet bygger på community connector-modellen, där en samhällskontakt agerar som mellanhand för att koppla patienter till stöttande resurser. Modellen, som utvecklats genom workshops, strävar efter att skapa ett mer omfattande stöd utanför vården, I artikeln presenterar forskarna Tillsammans-projektet, som syftar till att förbättra socialt stöd genom samverkan mellan civilsamhället och vården. Projektet bygger på community connector-modellen, där en samhällskontakt agerar som mellanhand för att koppla patienter till stöttande resurser. Modellen, som utvecklats genom samskapande workshops, strävar efter att skapa ett mer omfattande stöd utan
Anterior cord herniation is due to a ventral displacement of the spinal cord through a defect in the dura and/or arachnoid.1 Though the condition is rare, some case reports are available.1-3 The neurological symptoms can slowly deteriorate over several years.3 A Brown-Séquard-like syndrome is the most common presenting neurological finding.2,4 Asymptomatic cases may be discovered incidentally.4 Ho
Experience of abuse as a life event is common among men in a psychiatric care context. Systematically charting life events and abuse plays a central role within psychiatric and mental health nursing and could improve the understanding of the patient’s life situation. The aim of the study was to explore the life course of male psychiatric patients who had experienced domestic abuse as victims and a
As in most cultural contexts and theoretical conceptualizations of peacebuilding, the fulfilment of justice and the sustainment of peace are intimately related in the Arab-Islamic frame of reference. In the Qur’an and Islamic philosophy, there is a direct correlation between establishing a just social order and the notion of peacebuilding (Abu-Nimer 2006). Guidelines are set forth for building a so
What are we subjected to when presented with stories about art's past in the context of classrooms or collections? In order to prepare students for a profession in the humanities or in the field of artistic production and reception at large, art history courses in higher education are obliged to provide them with an understanding for the collection of texts, debates or works of art that are consid
The respiratory epithelium consists of multiple, functionally distinct cell types and is maintained by regionally specific progenitor populations that repair the epithelium following injury. Several in vitro methods exist for studying lung epithelial repair using primary murine lung cells, but isolation methods are hampered by a lack of surface markers distinguishing epithelial progenitors along t
Achieving CRISPR Cas9-based manipulation of mitochondrial DNA (mtDNA) has been a long-standing goal and would be of great relevance for disease modeling and for clinical applications. In this project, we aimed to deliver Cas9 into the mitochondria of human cells and analyzed Cas9-induced mtDNA cleavage and measured the resulting mtDNA depletion with multiplexed qPCR. In initial experiments, we fou
