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Babesia divergens Shows Equal Predilection for Human ABO Blood Types in an In Vitro Erythrocyte Preference Assay.

Babesia is spread to humans via ticks or blood transfusions. Severity of Plasmodium falciparum malaria is strongly correlated to the ABO blood group of the patient. Babesia divergens is an intraerythrocytic parasite with many similarities to malaria, but the impact of ABO on the susceptibility to and progression of the infection in humans is unknown. We have now cultured B. divergens in human

Mosaic chromosomal alterations in hematopoietic cells and clinical outcomes in patients with multiple myeloma

Mosaic chromosomal alterations (mCAs) in hematopoietic cells increase mortality and risk of hematological cancers and infections. We investigated the landscape of mCAs and their clinical consequences in 976 patients with multiple myeloma undergoing high-dose chemotherapy and autologous stem cell support (ASCT) with median 6.4 years of follow-up. mCAs were detected in the stem cell harvest product

Xputer : bridging data gaps with NMF, XGBoost, and a streamlined GUI experience

The rapid proliferation of data across diverse fields has accentuated the importance of accurate imputation for missing values. This task is crucial for ensuring data integrity and deriving meaningful insights. In response to this challenge, we present Xputer, a novel imputation tool that adeptly integrates Non-negative Matrix Factorization (NMF) with the predictive strengths of XGBoost. One of Xp

Matkultur och matvanor i yrkesgrupper med oregelbunden arbetstid

Sambanden mellan matvanor, välbefinnande och hälsotillstånd har länge varit kända. Under 1970- och 1980talen uppmärksammades matens betydelse som riskfaktor för hjärt- och kärlsjukdomar. En stor andel anställda i tung industri hade skiftarbeten. Den höga relativa dödligheten var överrepresenterad i dessa arbetaryrken. I forskningen kring orsaker till överdödligheten betonade man inte bara medicins

Contrasting vulnerability reduction measures for critical infrastructures: using power system and regional inoperability input-output models

Critical infrastructures provide society with services that are essential for its functioning and extensive disruptions of these give rise to large societal consequences. Vulnerability analysis gives important decision information concerning improving their ability to withstand strains. To analyze vulnerabilities in infrastructures models for estimating consequences due to failures are needed. Con

Functional dissection of inherited non-coding variation influencing multiple myeloma risk

Thousands of non-coding variants have been associated with increased risk of human diseases, yet the causal variants and their mechanisms-of-action remain obscure. In an integrative study combining massively parallel reporter assays (MPRA), expression analyses (eQTL, meQTL, PCHiC) and chromatin accessibility analyses in primary cells (caQTL), we investigate 1,039 variants associated with multiple

SARS-CoV-2 in exhaled aerosol particles from covid-19 cases and its association to household transmission

BACKGROUND: Covid-19 transmission via exhaled aerosol particles has been considered an important route for the spread of infection, especially during super-spreading events involving loud talking or singing. However, no study has previously linked measurements of viral aerosol emissions to transmission rates.METHODS: During Feb-Mar 2021, covid-19 cases that were close to symptom onset were visited

Virtuell gromning - En framställning om gällande och möjliga utredningsmetoder

Gromning är brottet där en vuxen tar kontakt med ett barn under 15 år för att träffas i sexuellt syfte, och återfinns i Brottsbalken 6 kap. 10 a §. Idag är internet den vanligast brottsplatsen för gromningförövare. Framställningen granskar de metoder det svenska rättsväsendet använder idag vid identifikation, bevisföring och lagföring av en gromningförövare. De mest använda metoderna är polisens sGrooming is the designation of a crime where an adult initiates contact with a child under 15 years with the intention of committing a sexual offence, and the Swedish regulation of grooming is found in the Swedish Criminal Code (Brottsbalken, SFS 1962:700) chapter 6 section 10 a. Today, the most common crime scene for grooming is the internet. This petition reviews methods that the Swedish judicia

Från sinnessjukhus till öppenvård - En undersökning av rättighetsutvecklingen inom den svenska psykiatriska tvångsvården från 1929 års sinnessjuklag till dagens LPT

Denna uppsats behandlar den rättighetsutvecklingen på den psykiatriska tvångsvårdens område från 1900-talets första hälft fram till idag. Det som undersöks är hur lagstiftningen på den psykiatriska tvångsvårdens område har förhållit sig till det svenska fri- och rättighetsskyddets framväxt. De psykiatriska tvångsvårdslagar som undersöks är 1929 års sinnessjuklag, LSPV och nu gällande LPT. Mot baThis paper discusses the development of the compulsary psychiatric care from the first half of the 20th century until today. What is being exmined is how the legislation on the field of the complusary psychiatric care has been related to the rise of human rights in Sweden. The legislations that have been exmined is the law regarding mentally ill from 1929, LSPV and the law currently in practice,

Steel Database Analysis

In this thesis the Plantfacts database is investigated, which contains data about steel plants from all over the world. The purpose is to evaluate wheter there is a coupling between primary and secondary steel and different types of steel plants in downstream processes. To achieve this, the database has been reformatted using Visual Basic for Applications (VBA) in Excel. Initially, the Plantfacts

A Method for Evaluating and Mapping Terrestrial Deposition and Preservation Potential- for Palaeostorm Surge Traces. Remote Mapping of the Coast of Scania, Blekinge and Halland, in Southern Sweden, with a Field Study at Dalköpinge Ängar, Trelleborg

Studier av palaeostormfloder ger bakgrund till inom vilka intevall stormar av olika storlek förväntas återkomma och träffa olika områden. Denna information kan användas vid modellering, riskbedömning och stadsplanering. Genom att använda de marina ekvationerna av Nittrouer och Sternberg (1981; The formation of sedimentary strata in an allochthonous shelf environment: the Washington continental sheStudies of palaeostorm surges provides background into at what frequencies storms of different magnitudes are expected to return and hit different areas. This information can be used when modelling, doing risk assesments and city planing. Using the marine equations of Nittrouer and Sternberg (1981; The formation of sedimentary strata in an allochthonous shelf environment: the Washington continenta

Gymnasielagen "It is nice that it came, but it is a shit law": Experiences and Perspectives of People Affected by One of Sweden's Temporary Migration Laws

In 2017 the Upper Secondary School Act [Hereafter gymnasielag/en] was adopted in Sweden and provided temporary residence permits and a chance of permanent residency to ‘unaccompanied refugee minors’ who previously had been denied asylum. This study includes voices of four young people who have managed to fulfil this journey from temporary permits to permanent. Moreover, three people who through va

Rådgivaransvar - Vårdslös juridisk rådgivning i inom- och utomobligatoriska förhållanden

Advokaters skadeståndsrättsliga rådgivaransvar bygger på culpaprincipen om inget annat avtalats. Av 1 kap. 1 § SkL framgår att ersättning för ren förmögenhetsskada kräver stöd i lag eller avtal. Juridisk rådgivning sker oftast i uppdragsförhållanden. Advokatens ansvar kallas ofta för professionsansvar och syftar på de specialkunskaper advokaten, som juridisk expert, förväntas ha som medlem i Advok

Traditionsprincipen eller avtalsprincipen? Borgenärsskyddet i förändring

Sammanfattning Enligt svensk rätt krävs det att parterna till en transaktion har vidtagit ett sakrättsligt moment för att en förvärvare av lös egendom ska vara skyddad mot överlåtarens borgenärer. Vilket sakrättsligt moment som uppställs varierar beroende på vilken typ av egendom som transaktionen rör. Vid förvärv av lösöre vinner köparen som huvudregel skydd mot säljarens borgenärer först när vaSummary Swedish law requires that the parties to a transaction have fulfilled a controllable measure in order for a buyer of movable property to obtain protection against the seller’s creditors. What kind of controllable measure that needs to be carried out varies depending on what type of property the transaction concerns. When the purchase concerns chattels the main rule is that the buyer recei

Publication in nature 0

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model 5 9 2 | N A T U R E | V O L 5 4 8 | 3 1 A U g U s T 2 0 1 7 LETTER doi:10.1038/nature23664 Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model Tetsuhiro Kikuchi1, Asuka Morizane1, Daisuke Doi1, Hiroaki Magotani1, Hirotaka Onoe2, Takuya Hayashi2, Hiroshi Mizuma2, sayuk

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_nature_0.pdf - 2026-05-06

Flyttningsförbudets förenlighet med barnets bästa – i ljuset av lex lilla hjärtat

Inom den sociala barnavården och familjehemsplaceringar av barn finns det tre grundtankar, kontinuitet, flexibilitet och närhet. Vid en familjehemsplace-ring med stöd av lagen med särskilda bestämmelser om vård av unga ska vår-den vara inriktad på att den unga ska återförenas med sina föräldrar, men det finns undantag. Flyttningsförbudet stadgas i 24 § LVU och ger möjligheten att införa ett förbudIn the field of child welfare there are three fundamental principles: continuity, flexibility and proximity. In the case of a family home placement according to The Care of Young Persons Act, the care must be aimed at reuniting the young person with their parents, but there are exceptions. Prohibition of relocation is regulated in section 24 of The Care of Young Persons Act and pro-vides the possi