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Regulation of eukaryotic aquaporins

Membrane-bound water channels known as aquaporins (AQPs) facilitate water transport across biological membranes along osmotic gradients. Since all living cells depend on their ability to maintain water homeostasis, this must be tightly regulated. In eukaryotes, this is achieved by gating, which involves a conformational change of the protein, thereby physically blocking water transport, or by traf

Community Currencies as Means of Local Economic Empowerment : Innovations from Mombasa and Nairobi to Kisumu, Kenya

Community currencies have emerged as a tool for building more inclusive local economic development and governance. Grassroots organisations in Nairobi and Mombasa (Kenya) have been experimenting with this form of local monies. Communities in informal settlements in Kisumu have shown interest in introducing their own community currency. Challenges remain concerning the best diffusion strategy of su

The Governance of Global Innovation Systems : Putting Knowledge in Context

Technological innovation increasingly depends on multiscalar actor networks and institutions. However, the developers of many conceptual frameworks explaining innovation success have paid only limited attention to this new reality, due to their focus on regions and countries as agents that shape innovation governance and as containers that provide institutional conditions for innovation success. I

Något om värdeförändring vid återvinning i konkurs

Inom civilrätten uppstår emellanåt behovet av att återställa ett förhållande så att det i möjligaste mån återspeglar de omständigheter som i ett specifikt skede tidigare gällde i relationen mellan de involverade. Sådant behov kan t.ex. uppstå vid ogiltighet alternativt hävning av kontrakt i avtalsrätten, vindikation i sakrätten eller återvinning i konkursrätten. Att rent faktiskt skruva tillbaka t

Marigó Oulis, Värdeersättning vid återgång

I denna anmälan av doktorsavhandlingen Värdeersättning vid återgång, författad av Marigó Oulis, Uppsala, väcks å ena sidan frågor rörande dels avhandlingens något otraditionella upplägg, dels en viss spretighet avseende vilka spörsmål som egentligen står i fokus för studien. Å andra sidan hyllas både det ambitiösa grundarbete som genomgående präglar verket samt flera av de utförliga resonemang som

Finite-size scaling analysis of protein droplet formation

The formation of biomolecular condensates inside cells often involve intrinsically disordered proteins (IDPs), and several of these IDPs are also capable of forming dropletlike dense assemblies on their own, through liquid-liquid phase separation. When modeling thermodynamic phase changes, it is well known that finite-size scaling analysis can be a valuable tool. However, to our knowledge, this ap