Filetype
Background: Psychiatric disorders have been associated with venous thromboembolism (VTE). However, to our knowledge, no nationwide study has examined the familial association between VTE and psychiatric disorders. Objectives: We took a pedigree-based approach and examined the risk of psychiatric disorders in offspring from extended pedigrees according to the densities of VTE in pedigrees. Methods:
This co-authored article develops Border Work (BW) as a methodological approach which is under explored in socio-legal scholar-activism, through analysing two distinct examples. While both examples depart from feminist methodology, the differences are stark: Noor, excluded from democratic processes, faced deportation risks, while we, with institutional support, engaged in public mobilizations with
Objective: To identify and quantify risk factors for incident knee osteoarthritis (KOA) across the lifespan. Methods: This systematic review and meta-analysis identified eligible studies from seven electronic databases and three registries. Longitudinal cohort studies or randomised controlled trials evaluating participants who developed incident symptomatic and/or radiographic KOA were included. T
OBJECTIVE: Childhood obesity may impact the risk of islet autoimmunity (IA). The trajectory of BMI through childhood resembles the early peak incidence of first-appearing autoantibodies against insulin (IAA-first) but not GAD65 (GADA-first). We studied whether a child's BMI can impact the age-related risk of first-appearing IA phenotypes.RESEARCH DESIGN AND METHODS: We identified 7,724 children at
Accurate labels are critical for deriving robust machine learning models. Labels are used to train supervised learning models and to evaluate most machine learning paradigms. In this paper, we model the accuracy and cost of a common weak labeling process where annotators assign presence or absence labels to fixed-length data segments for a given event class. The annotator labels a segment as "pres
Telomere length (TL) early in life often shows high heritability and may predict telomere shortening later in life and life expectancy. Yet, there is limited data about what influences TL and TL change at early developmental stages. It is debated whether early-life TL is determined at conception or shaped by early environmental conditions. Here, we investigate whether TL and telomere shortening ar
Work and working conditions are fundamental social determinants of health. Climate change poses an urgent and growing threat to workers' health, through both direct exposure to environmental hazards and indirect exacerbation of social and health inequalities. Occupational health, which focusses on the promotion of mental and physical health and well-being of workers, is a key but often overlooked
Objectives: This study aimed to assess the relationship between dietary intake and disease outcomes in patients with radiographic axial spondyloarthritis (r-axSpA), focusing on inflammation and disease activity, while also evaluating other health outcomes, and to compare dietary intake between patients and controls. Method: In a cross-sectional analysis, we studied 295 patients with r-axSpA (modif
BACKGROUND: The transport of large proteins across the glomerular capillary wall (GCW) may increase several fold in glomerular diseases. The occurrence of IgM in urine is a consequence of the presence of large defects or shunts in the GCW, whereas albuminuria is probably a result of an altered charge- and size-selectivity of the GCW. In order to examine whether patho-morphological differences infl
The increasing implementation of next-generation sequencing technologies in the clinical context and the expanding commercial offer of genetic tests directly-toconsumers has increased the availability of previously inaccessible genetic information. A particular concern in both situations is how the volume of novel information will affect the processing of genetic and genomic information from minor
Background- This nationwide study sought to determine age- and gender-specific familial risks in siblings hospitalized for venous thromboembolism (VTE). Methods and Results- The Swedish Multigeneration Register on 0- to 75-year-old subjects was linked to the Hospital Discharge Register for the years 1987-2007. Standardized incidence ratios were calculated for individuals whose siblings were hospit
Spatial Data Infrastructures (SDIs) have been identified essential for environmental management and development activities around the world. Meanwhile, development of frameworks to monitor and evaluate SDIs is currently an important research area. This study proposes Balanced Scorecard (BSC) as a framework for evaluation and monitoring the implementation of SDIs. The concept and advantages of BSC
This paper describes the fabrication of efficient ultra-thin silicon transmission detectors for use as pre-cell detectors in single-ion experiments on living cells at the Lund Ion Beam Analysis Facility. More than 40 detectors of different thicknesses down to 5 mu m have been fabricated and packaged. The main design considerations were very low leakage current (below 9 nA) and low full depletion v
BACKGROUND: Differences in the estrogen receptor (ER) status of tumors may explain ambiguities in epidemiologic studies between the blood concentrations of enterolactone and breast cancer. To our knowledge, the association between enterolactone and ERbeta-defined breast cancer has previously not been examined.METHODS: A nested case-control study within the Malmö Diet and Cancer cohort used 366 cas
The overall aim of this thesis was to describe parent’s experiences, reactions and needs in connection with a routine ultrasound examination during pregnancy when the foetus was found to have an abnormal ultrasound finding. The data collection began in February 2005 and the one year cohort study was completed by March 2006. The participants in this study were each asked if they would also consid
Popular Abstract in English Darwin’s masterpiece “On the origin of species” describes how populations (one group of individuals from the same species that can easily mate with each other and that occupy the same geographic area) evolve through the process of natural selection, which can be shortly abbreviated as the survival of the fittest. More specifically, the individuals within one population The gene (Pgi) encoding the enzyme phosphoglucose isomerase (PGI) which plays a central role in the main pathways of carbon metabolism has been shown to be of adaptive significance in a wide range of different species. Earlier studies of enzyme electromorph variation in the grass Festuca ovina suggest that variation in cytosolic PGI (PGIC) may be involved in the adaptive response of F. ovina to th
The purpose of this study is to investigate the use of corpus linguistics, with a specific focus on the concordances in teaching and learning English in Vietnam. The concordance samples provide teachers and students with the information about the different patterns of use and structure that can be found for each word. I have designed a new kind of linguistics exercises on the basic of the selected
We have previously identified C1 domain-containing phosphatase and TENsin homologue (C1-TEN) as being an intracellular binding partner for Axl receptor tyrosine kinase (RTK). C1-TEN is a tensin-related protein that houses an N-terminal region with predicted structural similarity to PTEN. Here, we report our observations on the effects of ectopic expression of C1-TEN in HEK293 cells, which resulted
One challenging task in building (bio)chemical sensors is the efficient and stable immobilization of receptor on a suitable transducer. Herein, we report a method for covalent immobilization of molecularly imprinted core-shell nanoparticles for construction of robust chemical sensors. The imprinted nanoparticles with a core-shell structure have selective molecular binding sites in the core and mul
