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OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>

In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of

Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly

Measurements are presented of inclusive charm and beauty cross sections in e(+)p collisions at HERA for values of photon virtuality 12 <= Q(2) = 60 GeV2 and of the Bjorken scaling variable 0.0002 <= x <= 0.005. The fractions of events containing charm and beauty quarks are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured

Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E

Kursen behandlar: Direkta och iterativa lösningsmetoder för olika problem i lineär algebra, såsom lineära ekvationssystem, egenvärdesproblem och minsta-kvadratmetoden, Matris- och vektornormer, ortogonalisering, projektion, matrisfaktoriseringar, direkta och iterativa lösare, konditionstal, stabilitet hos en metod, komplexitet hos en algoritm, Tillämpning av ovanstående begrepp för att konThe course covers: Direct and/or iterative solution methods for various linear algebra problems such as linear systems of equations, eigenvalue problems and the least-squares method,  Matrix and vector norms, orthogonalisation, projection, matrix factorisations, direct and iterative solvers, condition numbers, stability of a method, complexity of an algorithm,  Applying these con

The course will introduce and elaborate on various theoretical perspectives of war and peace in the Israeli-Palestinian conflict. Central issues to be discussed and compared over time are (1) the causes of the conflict, such as identity, nationalism, religion, territory and great power politics; (2) the Middle Peace Process (MEPP), which highlights the various agreements, peacebuilding by third pa

I denna kurs kommer du att utforska teoretiska och praktiska koncept avseende hållbar turism samt hur planering kan utföras i ett GIS. Du lär dig också praktiska och teoretiska övningar i hur ett känsligt naturområde kan kategoriseras i känslighet för turism, samt hur GIS kan användas för fältmätningar av turistpåverkan, samt för analys och visualisering. Dessutom undersöker vi hur ett förenklat bIn this course you will explore theoretical and practical concepts of sustainable tourism planning and how tourism can be planned using a GIS. Furthermore a simplified Tourism Decision Support System (TDSS) will be explored and how such a system can be linked to a GIS. This course includes practical and theoretical exercises regarding categorisation of sensitivity for land exposed to tourism and h

The excited state decay kinetics of chromatophores of the purple photosynthetic bacterium Rhodospirillum rubrum have been recorded at 77 K using picosecond absorption difference spectroscopy under strict annihilation free conditions. The kinetics are shown to be strongly detection wavelength dependent. A simultaneous kinetic modeling of these experiments together with earlier fluorescence kinetics

Traditionally, biogenic volatile organic compound (BVOC) emissions are often considered a unidirectional flux, from the ecosystem to the atmosphere, but recent studies clearly show the potential for bidirectional exchange. Here we aimed to investigate how warming and leaf litter addition affect the bidirectional exchange (flux) of BVOCs in a long‐term field experiment in the Subarctic. We also ass

The course explores and explains the historical processes of rapid industrialisation and socio-economic modernisation in Pacific Asia. First, fundamental factors and forces behind the rise of Asia’s first industrial nation, Japan, are analysed. Japan is also contrasted against the early failures of modernisation in Imperial China. Secondly, explanations are provided for the emergence of Taiwan,

I kursen studeras kommunismens utveckling efter andra världskriget, med särskild inriktning på situationen i Öst- och Centraleuropa. Syftet är att studera kommunismens utveckling under det kalla kriget från konferensen i Jalta år 1945 till Sovjetunionens sammanbrott år 1991 och dess följder under 1990- och 2000- talet. Perspektiven som anläggs är både genetiska och genealogiska.The course addresses the development of communism after World War II, focusing on the situation in Central and Eastern Europe. The aim is to study the development of communism during the Cold War, from the Yalta conference in 1945 to the fall of the Soviet Union in 1991, and its consequences in the 1990s and early twenty-first century. The subject is addressed from both genetic and genealogical pe

Recent neuroscientific and technical developments of brain machine interfaces have put increasing demands on neuroinformatic databases and data handling software, especially when managing data in real time from large numbers of neurons. Extrapolating these developments we here set out to construct a scalable software architecture that would enable near-future massive parallel recording, organizati

https://www.ses.lu.se/en/sites/ses.lu.se.en/files/2025-09/Kp_SMMV26_eng_VT26_rev_250829.pdf - 2025-11-12

André from HungaryWhy did you choose this programme?"I have studied a Bachelor’s in Mechatronics engineering and was interested in control and machine learning. So, when I was searching for programmes, I found this programme at Lund University and I decided to come."How do you like the programme so far? "It's been very nice so far and I am very satisfied. This programme is very much a ‘build your

https://www.lunduniversity.lu.se/lubas/i-uoh-lu-tamsr/what-andre-says-about-masters-machine-learning-systems-and-control - 2025-11-12

BERN02. Kursens övergripande mål är att låta studenterna arbeta med och kombinera två områden för dataanalys inom beräkningsvetenskap: reproducerbara arbetsflöden och statistisk inlärning. Detta inbegriper att kunna skapa rapporter där programmeringskod, resultat och rapporttext kombineras i samma dokument, tillämpat på ett urval av vanliga metoder i statistisk parametrisk modelleringBERN02. The overall learning outcome for the course is to let the students work with and combine two fields for data analysis in computational science: reproducible work flows and statistical learning. This includes to be able to create reports where programming code, results and text are combined in the same document, applied on a selection of common methods in statistical parametric mode