Search results

Transfusion-related acute lung injury (TRALI) remains a leading cause of transfusionrelated deaths. In most cases, anti-leukocyte antibodies in the transfusion product trigger TRALI, but not all anti-leukocyte antibodies cause TRALI. It has been shown that the anti-major histocompatibility complex (MHC) class I antibody 34-1-2S (anti-H-2Kd) causes TRALI in BALB/c mice (MHC class I haplotype H-2Kd)

Background and Purpose-We have previously shown that delivery of brain-derived neurotrophic factor (BDNF) through direct intrahippocampal gene transduction with a viral vector suppresses the formation of new dentate granule cells triggered by global forebrain ischemia. Here, we investigated whether inhibition of endogenous BDNF alters ischemia-induced neurogenesis in the dentate gyrus. Methods-Rat

Abstrakt Bakgrund: Kvinnlig könsstympning definieras som delvis eller totalt avlägsnande av kvinnans könsdelar eller åsamkande av annan skada av icke-medicinska skäl. 2014 beräknades enligt WHO mer än 125 miljoner flickor och kvinnor vara könsstympade. I Sverige uppskattas det leva cirka 38 000 könsstympade kvinnor. Ingreppet kan medföra kronisk smärta, svårigheter i samband med miktion och meAbstract Background: Female genital mutilation (FGM) comprises all procedures that involve partial or total removal of the external female genitalia, or other injury to the female genital organs for non-medical reasons. According to WHO, 2014 more than 125 million women and girls were estimated to be cut. In Sweden, around 38 000 women are thought to have been victims of the procedure. Female g

Background This study was conducted at a business unit at the Company, a leading global consumer goods company based in Europe, working in an increasingly hostile environment due to market deregulation and international competition. The business unit was recently separated from previously being integrated in other units and now have high targets to meet. To reach these targets, the rate of innovat

Enzymes that affect glycoproteins of the human immune system, and thereby modulate defense responses, are abundant among bacterial pathogens. Two endoglycosidases from the human pathogen Streptococcus pyogenes, EndoS and EndoS2, have recently been shown to hydrolyze N-linked glycans of human IgG. However, detailed characterization and comparison of the hydrolyzing activities have not been performe

In the present study, two types of micro-pin–fin configurations were fabricated on silicon surfaces by a dry etching method, i.e., staggered pin fins (#1) and aligned pin fins with empty areas (#2). The micro-pin–fin surfaces were then further modified by depositing FeMn oxide nanoparticles (∼35 nm) electrostatically for 8 h and 16 h, respectively, namely #1-8h, #1-16h, #2-8h and #2-16h. Subcooled