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Contextual adaptation, implementation, and outcomes of individual placement and support: a case study

Background: Implementing the evidence-based Individual Placement and Support (IPS) model in welfare states like Sweden faces contextual challenges that often necessitate local adaptations to enhance fit and effectiveness. While fidelity assessments aim to ensure effective outcomes, adaptations may lead to unintended drift from core components. The Model for Adaptation Design and Impact (MADI) helpBackground: Implementing the evidence-based Individual Placement and Support (IPS) model in welfare states like Sweden faces contextual challenges that often necessitate local adaptations to enhance fit and effectiveness. While fidelity assessments aim to ensure effective outcomes, adaptations may lead to unintended drift from core components. The Model for Adaptation Design and Impact (MADI) help

Energy efficiency at what cost? Unjust burden-sharing of rent increases in extensive energy retrofitting projects in Sweden

Although renovation costs can lead to rent increases in energy retrofitting, it is often assumed that reductions in energy costs will counterbalance the rent increase. In Swedish multifamily housing, energy costs for heating are however generally included as a fixed component in the monthly rent, meaning that the rent increase after energy retrofitting corresponds to the net change in rent level a

Biological Activities of Natural and Semi-Synthetic Pseudo-Guaianolides: Inhibition of Transcription Factors

Damsin (1) is a natural sesquiterpene lactone (SL) isolated from Ambrosia arborescens Mill., a plant used in the Andes as antiinflammatory medicine. This natural product is an inhibitor of NF- κB, a protein complex that controls the transcription of many genes in mammalian cells, and has a potential for standing model for the development of new anti-cancer lead structures. In order to improve the