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Some Physical and Environmental Aspects of Shallow Ice Covered Lakes : Emphasis on Lake Vendyurskoe, Karelia, Russia.

The ice cover presence on the surface of a lake insulates the water body from the atmosphere. This prevents or reduces the influence of processes which depend on the exchange between the atmosphere and the water surface. This implies significant reduction or elimination of some processes taking place at the open water surface; for instance, a substantial reduction in solar energy penetrating to th

"A Scrapbook of You + Me" : Intermediality and Bookish Nostalgia in J.J. Abrams and Doug Dorst's S.

Abstract på danska:Artiklen læser det eksperimentende bog-værk S. (2013), af Doug Dorst og J.J. Abrams, som en refleksion over, og et udtryk for den trykte romans forandrede status i en digital tidsalder. Som en eksperimenterende roman med gulnede sider og håndskrift i marginen synes S. at reflektere en materiel vending i literaturen. Den idealiserer bogmediet som et rum for materialitet og intimiThis article reads J. J. Abrams and Doug Dorst's S. (2013) as a reflection of the changing status and function of the printed novel in the digital age. As an experimental novel with yellowing pages and handwriting in the margins, S. appears to reflect a “material turn” in literature. It celebrates the book as a space of intimacy and memory, positioned in opposition to new digital media. However, t

Coronary Artery Disease in a Population-Based Cohort of Biopsy-Proven Giant Cell Arteritis in Southern Sweden

Background/Purpose: The aim of this study was to estimate the incidence rate and prevalence of coronary artery diseases (CAD) in patients with temporal artery positive giant cell arteritis (TAB+GCA) from a defined population in southern Sweden, and to describe characteristics of CAD in this sample.Methods: The study cohort consisted of 1202 patients (71.9% women) diagnosed with TAB+GCA between 199

Associations and gastrointestinal symptoms in women with endometriosis in comparison to women with irritable bowel syndrome : a study based on a population cohort

Background: Endometriosis and irritable bowel syndrome (IBS) have similar symptoms, pathogenesis, and risk factors. These diagnoses often coexist and are frequently misdiagnosed leading to diagnostic delays. This study of a population-based cohort aimed to investigate associations relating to endometriosis and IBS and to compare gastrointestinal symptoms between endometriosis and IBS. Method: The

Structural and Functional Analyses of Xyloside-primed Glycosaminoglycans

Glycosaminoglycans (GAGs) are polysaccharides produced by essentially all mammalian cells. Due to their enormous structural diversity, they are involved in many biological processes both in health and disease, including all stages of tumor progression. GAGs are normally attached to a core protein as a part of a proteoglycan; however, GAG biosynthesis can be induced by compounds composed of a xylos

Plasma and cerebrospinal fluid neurofilament light concentrations reflect neuronal damage in systemic lupus Erythematosus

BACKGROUND: Neuronal damage in systemic lupus erythematosus (SLE) is common, but the extent and mechanisms are unclear. Neurofilament light (NfL) concentrations rise in plasma and cerebrospinal fluid (CSF) during neuronal damage in various neurological disorders. In this cross-sectional study, plasma and CSF concentrations of NfL were explored as a marker of neuronal damage in SLE.METHODS: Seventy

Plasma pTau 217/β-amyloid 1–42 ratio for enhanced accuracy and reduced uncertainty in detecting amyloid pathology

Blood biomarkers have the potential to revolutionize Alzheimer's disease diagnosis, offering advantages over CSF and PET due to their accessibility, scalability and cost-effectiveness. This study evaluated the effectiveness of individual plasma biomarkers, such as phosphorylated Tau (pTau) 217, as well as biomarker combinations, with a focus on the pTau 217/β-Amyloid (Aβ) 1–42 ratio to predict amy

Discordant Neural Xenografting: Analysis and Modulation of Immune Responses

Popular Abstract in Swedish Transplantation av dopaminceller från mänskliga foster kan förbättra funktionen hos patienter med Parkinsons sjukdom (Lindvall 1997, Björklund 2000a). Man har kunnat visa att transplantaten har återställt dopaminproduktionen i striatum till normala nivåer i flera fall, och till 70-80% av normalt i majoriteten av de patienter som transplanterats i Lund. Transplantaten haTransplantation of embryonic human neural tissue can restore function in patients with Parkinson’s disease, but there is a severe shortage of donor tissue which limits the applicability of the technique. Embryonic neural tissue from other species, xenogeneic tissue, would provide a readily accessible donor tissue with the potential to help patients if the immunological reactions in the host could

EQ-5D utility, response and drug survival in rheumatoid arthritis patients on biologic monotherapy : A prospective observational study of patients registered in the south Swedish SSATG registry

Objectives Biologic agents have dramatically changed treatment of rheumatoid arthritis (RA). To date only scarce head-To-head data exist especially when the biological therapies are given as monotherapy without concomitant disease modifying drugs (DMARDs). Thus the objective of the current study is to evaluate treatment response of all available biological therapies with special focus on utility (

The XXL Survey : VI. the 1000 brightest X-ray point sources

Context. X-ray extragalactic surveys are ideal laboratories for the study of the evolution and clustering of active galactic nuclei (AGN). Usually, a combination of deep and wide surveys is necessary to create a complete picture of the population. Deep X-ray surveys provide the faint population at high redshift, while wide surveys provide the rare bright sources. Nevertheless, very wide area surve

Helicobacter pylori screening in clinical routine during hospitalization for acute myocardial infarction

Background: Potent antithrombotic therapy has significantly improved prognosis for patients with acute myocardial infarction (AMI), however, at a price of increased bleeding risk. Chronic gastric infection with Helicobacter pylori (Hp) commonly causes upper gastrointestinal bleeding and is proposed as a risk factor for subsequent bleeding post AMI. The prevalence of active Hp in a current AMI popu

10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1) : A multicentre randomised trial

Background If carotid artery narrowing remains asymptomatic (ie, has caused no recent stroke or other neurological symptoms), successful carotid endarterectomy (CEA) reduces stroke incidence for some years. We assessed the long-term effects of successful CEA. Methods Between 1993 and 2003, 3120 asymptomatic patients from 126 centres in 30 countries were allocated equally, by blinded minimised rand

Association Between Soft Drink Consumption and Mortality in 10 European Countries

Importance: Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk is unknown and has been understudied in European populations to date.Objective: To examine the association between total, sugar-sweetened, and artificially sweetened soft drink consumption and subsequent total and cause-specific mortality.Design, Setting, and Participants: This populatio

The immune microenvironment of colorectal cancer - Relationship with survival, sidedness, and pre-diagnostic anthropometry

Colorectal cancer (CRC) is the third most common cancer worldwide. Increasing evidence suggests that CRC should be considered a heterogeneous disease, with multiple differences between proximal and distal tumours. The immune system may, depending on the context, promote or inhibit tumour growth, and different immune cell subsets have been found to be associated with impaired or improved prognosis

Assessment of Demographic, Genetic, and Imaging Variables Associated with Brain Resilience and Cognitive Resilience to Pathological Tau in Patients with Alzheimer Disease

Importance: Better understanding is needed of the degree to which individuals tolerate Alzheimer disease (AD)-like pathological tau with respect to brain structure (brain resilience) and cognition (cognitive resilience). Objective: To examine the demographic (age, sex, and educational level), genetic (APOE-ϵ4 status), and neuroimaging (white matter hyperintensities and cortical thickness) factors

Canopy storage capacity of xerophytic shrubs in northwestern China

Abstract in UndeterminedThe capacity of shrub canopy water storage is a key factor in controlling the rainfall interception. Thus, it affects a variety of hydrological processes in water-limited arid desert ecosystems. Vast areas of revegetated desert ecosystems in Northwestern China are occupied by shrub and dwarf shrub communities. Yet, data are still scarce regarding their rainwater storage cap

Spectroscopic differences in posterior insula in patients with chronic temporomandibular pain

Chronic pain including temporomandibular disorder (TMD) pain involves a complex interplay between peripheral and central sensitization, endogenous modulatory pathways, cortical processing and integration and numerous psychological, behavioral and social factors. The aim of this study was to compare spectroscopic patterns of N-Acetyl-aspartate (NAA), total creatine (tCr), choline (Cho), myo-inosito

Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial

Background: Patent foramen ovale (PFO) is a contributor to embolic stroke of undetermined source (ESUS). Subgroup analyses from previous studies suggest that anticoagulation could reduce recurrent stroke compared with antiplatelet therapy. We hypothesised that anticoagulant treatment with rivaroxaban, an oral factor Xa inhibitor, would reduce the risk of recurrent ischaemic stroke compared with as

Blood- and tumor-based analyses for improved prognostics in lung cancer

Lung cancer is a common cancer type associated with poor prognosis. Even in the group of patients with earlystage tumors, for which curative treatment is possible, lung cancer recurrence is frequent. The aim of this thesis was to investigate the potential prognostic role of mutations in tumor specimens, blood-based proteins and circulating tumor DNA.In study I, we performed EGFR mutation detection