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This master’s thesis aims to support product-centered companies in their transition to a circular economy (CE) by developing a digital self-assessment and decision support tool. Circularity is a complex field that demands collaboration across multiple system levels. Although a wide range of frameworks, regulations and guidelines exist, the transition remains difficult for companies to navigate. Ex
Lignin is a by-product from the paper industry and has shown good liquid barrier properties according to previous studies. The objective of this work was therefore to study the liquid barrier properties of hydrotropic extracted lignin through steam explosion (STEX), obtained from spruce. The lignin was dissolved in three different solvents (concentrations: acetone 65 %v/v, ethanol (EtOH) 80%v/v an
This thesis studies the flood risks in Yogyakarta City, Indonesia, focusing on the Kali Belik River area, and explores the regulations and design principles aimed at enhancing flood risk reduction and management in the city. The discussion begins at the global level, analysing frameworks such as the Sendai Framework for Disaster Risk Reduction, and transitions to the local level, assessing the cha
Galectins are proteins that bind to carbohydrate structures, with high affinity for β-galactoside ligands that exists naturally in our bodies. They are involved in the development of various diseases, including central nervous system diseases and cancer proliferation. Galectin-1, which is the focus in this thesis, is related to anti-inflammatory and neuroprotective functions in the brain. Drug del
One measure required to reduce greenhouse gas emissions is changed consumption behaviours in affluent contexts. This might be motivated by sufficiency, and while the concept is often related to reduced material consumption, its practical implications regarding food consumption have not been explored to the same extent. To investigate how the literature on sufficient consumption may offer new insig
HPLC is one of the most widely used analytical techniques in the pharmaceutical industry used for separation and identification of compounds in complex formulations. Despite its advantages, HPLC method development remains challenging. This is due to the need to optimize multiple interdependent parameters simultaneously, while gaining high precision, reproducibility, and efficiency. Even minor cha
This thesis analyzes Socialstyrelsens (Swedish Social Services) guidelines for endometriosis healthcare, with the aim of understanding the social aspects of the medicalized field of endometriosis. Former research on transnational and Swedish endometriosis experience, studies on endometriosis guidelines and Socialstyrelsens’ guidelines for healthcare, is presented to contextualize the project. The
This study investigates teachers’ perspectives on the use of gamification in programming courses at Lund University’s Faculty of Engineering (LTH), focusing on implementation within the Moodle learning platform. Using a qualitative approach, semi-structured interviews were conducted with instructors who integrate gamification elements such as points, levels, progress bars, and immediate feedback i
CERN operates complex underground facilities, with the Large Hadron Collider (LHC) posing unique fire detection challenges due to ionising radiation, long tunnel spans, and variable ventilation. To address the limitations of aspirating smoke detectors in both current and future CERN facilities, Distributed Temperature Sensing (DTS) systems using radiation-resistant optical fibers are being exp
As industrial sectors and digital infrastructure expand, the global demand for high-volume, reliable manufacturing of thermal management solutions like heat exchangers continues to accelerate. This thesis investigates the design and optimization of an automated robotic assembly cell for heat exchanger production at Alfa Laval using Discrete Event Simulation (DES). The primary objective was to defi
α-CGRP 8-37 is a peptide fragment of calcitonin gene-related peptide and is commonly used as a CGRP antagonist in pharmacological research. CGRP signaling has been discussed in relation to neuroimmune mechanisms in psoriasis, but a practical development of α-CGRP 8-37 requires analytical methods and formulation strategies that can handle peptide instability, adsorption, and matrix effects. The aim
Energy management in cold logistics is critical for sustainable cold chain transportation. However, conventional reactive temperature control strategies often induce excessive energy consumption and mechanical wear due to rigid air temperature tracking and inability to anticipate system thermal dynamics. Guided by the Design Science Research (DSR) methodology, this study proposes a simulation-base
This thesis develops a Fourier-feature DeepONet surrogate model for predicting two-dimensional steady laminar flow fields around a rotating triangular obstacle. The aim is to learn the mapping from the obstacle rotation angle to the corresponding pressure, x-velocity, and y-velocity fields. A CFD dataset containing 121 cases was generated using ANSYS Fluent, covering rotation angles from 0° to 120
Many consumers say they want to shop more sustainably. But most retail websites do not make that easy. Walk through a typical online furniture store, and you will find sustainability information buried in product specifications or tucked away behind a separate filter tab. This happens right when you are already trying to balance price, looks, and whether the thing will actually fit in your living
Milk protein compositions play a pivotal role in physicochemical and technological properties of milk, particularly in rennet coagulation in cheese production. Conventional analytical methods such as sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and liquid chromatography–high resolution mass spectrometry (LC-HRMS) provide detailed protein characterization but require long an
This guide Addressing Inner Dimensions for Sustainability in Higher Education is aimed at Higher Education faculty from diverse disciplines. The target group is interested in expanding their sustainability knowledge and perspectives, integrating sustainability into their teaching practices, and enhancing their sustainability-related teaching approach by addressing inner dimensions. By inner dimens
OBJECTIVE: Avacopan (AVAC), an oral selective C5a receptor inhibitor, has been approved for treatment in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Outside randomized controlled studies, real-world data are scarce. The aim of this study was to provide further insight into the clinical experience of AVAC.METHOD: We analysed data from 16 patients with severe AAV include
Background Increased airflow is reported as helpful in reducing the sensation of breathlessness. This systematic review aimed to assess the effectiveness of airflow on breathlessness (primary outcome, measured using a validated tool at rest or during exercise) and health-related quality of life (secondary outcome) in people with serious respiratory illness. Methods We searched Ovid MEDLINE, Embase
Accurate mapping of earthquake-damaged buildings is essential for rapid post-disaster assessment and urban recovery planning. Very high-resolution (VHR) satellite imagery enables large-scale geospatial damage detection; however, conventional convolutional neural networks (CNNs) often struggle to model complex spatial dependencies and nonlinear damage patterns efficiently. To address these limitati
