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Total opioid-free general anaesthesia can improve postoperative outcomes after surgery, without evidence of adverse effects on patient safety and pain management : A systematic review and meta-analysis

Background: Opioid-based treatment is used to manage stress responses during surgery and postoperative pain. However, opioids have both acute and long-term side effects, calling for opioid-free anaesthetic strategies. This meta-analysis compares adverse events, postoperative recovery, discharge time from post-anaesthesia care unit, and postoperative pain, nausea, vomiting, and opioid consumption b

Effect of continuous positive airway pressure on weight and local adiposity in adults with obstructive sleep apnea : A meta-analysis

Rationale: Evidence suggests that continuous positive airway pressure (CPAP) treatment promotes weight gain in patients with obstructive sleep apnea (OSA). It is unclear whether weight gain is influenced by CPAP adherence or comorbid disorders. Objectives: To examine the CPAP effects on body mass index (BMI) and local adiposity and the potential moderators of CPAP effects on BMI in patients with O

Floral scent and pollinator visitation in relation to floral colour morph in the mixed-mating annual herb Collinsia heterophylla

Even though floral scent is of major importance for pollinator attraction, it is less investigated than other floral traits. Previous studies suggest the importance of joint exploration of olfactory and visual floral cues to understand plant–pollinator interactions. We investigated flower scents in Collinsia heterophylla, a bee-pollinated, annual herb a with mixed-mating system combining self- and

Gene expression profiling and chromatin immunoprecipitation identify DBN1, SETMAR and HIG2 as direct targets of SOX11 in mantle cell lymphoma

The SRY (sex determining region Y)-box 11 (SOX11) gene, located on chromosome 2p25, encodes for a transcription factor that is involved in tissue remodeling during embryogenesis and is crucial for neurogenesis. The role for SOX11 in hematopoiesis has not yet been defined. Two genes under direct control of SOX11 are the class- III β-tubulin gene (TUBB3) in neural cells and the transcription factor

Effectiveness of elevated intraocular pressure as a criterion for glaucoma referral after 6 years of follow-up

Purpose: To evaluate the long-term predictive value of the need to treat patients referred by optometric practitioners, regarding glaucoma, in Malmö, Sweden, using intraocular pressure (IOP) as the primary referral criterion. Patients and Methods: This retrospective study included 94 of 108 (87%) individuals referred to the Skåne University Hospital in Malmö, Sweden, for elevated IOP during 2012–

Cost Effectiveness of Primary Stenting in the Superficial Femoral Artery for Intermittent Claudication : Two Year Results of a Randomised Multicentre Trial

Objective: Invasive treatment of intermittent claudication (IC) is commonly performed, despite limited evidence of its cost effectiveness. IC symptoms are mainly caused by atherosclerotic lesions in the superficial femoral artery (SFA), and endovascular treatment is performed frequently. The aim of this study was to investigate its cost effectiveness vs. non-invasive treatment. Methods: One hundre

Spreading of Pain in Patients with Chronic Pain is Related to Pain Duration and Clinical Presentation and Weakly Associated with Outcomes of Interdisciplinary Pain Rehabilitation: A Cohort Study from the Swedish Quality Registry for Pain Rehabilitation (SQRP)

Introduction: The extent to which pain is distributed across the body (spreading of pain) differs largely among patients with chronic pain conditions and widespread pain has been linked to poor quality of life and work disability. A longer duration of pain is expected to be associated with more widespread pain, but studies are surprisingly scarce. Whether spreading of pain is associated with clini

Spatially different annual cycles but similar haemosporidian infections in distant populations of collared sand martins

BackgroundPopulations of long-distance migratory birds experience different environments and are consequently exposed to different parasites throughout their annual cycles. Though, specific whereabouts and accompanied host-parasite interactions remain unknown for most migratory passerines. Collared sand martins (Riparia riparia) breeding in the western Palaearctic spend the nonbreeding period in A

Patterns of pathologic lymph nodes in anal cancer : a PET-CT-based analysis with implications for radiotherapy treatment volumes

Background: This study investigates the patterns of PET-positive lymph nodes (LNs) in anal cancer. The aim was to provide information that could inform future anal cancer radiotherapy contouring guidelines. Methods: The baseline [18F]-FDG PET-CTs of 190 consecutive anal cancer patients were retrospectively assessed. LNs with a Deauville score (DS) of ≥3 were defined as PET-positive. Each PET-posit

Interaction between gad65 antibodies and dietary fish intake or plasma phospholipid n-3 polyunsaturated fatty acids on incident adult-onset diabetes : The epic-interact study

OBJECTIVE: Islet autoimmunity is associated with diabetes incidence. We investigated whether there was an interaction between dietary fish intake or plasma phospholipid n-3 polyunsaturated fatty acid (PUFA) concentration with the 65-kDa isoform of GAD (GAD65) antibody positivity on the risk of developing adult-onset diabetes. RESEARCH DESIGN AND METHODS: We used prospective data on 11,247 incident

Interventions to minimize blood loss in very preterm infants - A systematic review and meta-analysis

Blood loss in the first days of life has been associated with increased morbidity and mortality in very preterm infants. In this systematic review we included randomized controlled trials comparing the effects of interventions to preserve blood volume in the infant from birth, reduce the need for sampling, or limit the blood sampled. Mortality and major neurodevelopmental disabilities were the pri

Lifetime alcohol intake, drinking patterns over time and risk of stomach cancer : A pooled analysis of data from two prospective cohort studies

Alcohol consumption is causally linked to several cancers but the evidence for stomach cancer is inconclusive. In our study, the association between long-term alcohol intake and risk of stomach cancer and its subtypes was evaluated. We performed a pooled analysis of data collected at baseline from 491 714 participants in the European Prospective Investigation into Cancer and Nutrition and the Melb

Preterm or early term birth and risk of autism

OBJECTIVES: Preterm birth has been linked with increased risk of autism spectrum disorder (ASD); however, potential causality, sex-specific differences, and association with early term birth are unclear. We examined whether preterm and early term birth are associated with ASD in a large population-based cohort. METHODS: A national cohort study was conducted of all 4 061 795 singleton infants born

Structural analysis of X-flo measure system

This thesis is done in cooperation with Dresser Wayne AB in Malmö and the objective has been to investigate if it is possible to use the X-flo meter, see Figure 1, in an LPG-dispencer. An increased pressure is used in the LPG-system, which involves a higher risk of leaking and strength problems. During the development consideration has been taken to a new outlet, though other couplings are used in

Framtagning av model, för små frö till precisionssåmaskin

This thesis project was to develop a module for a forest precision seeder. The project is made at BCC AB. BCC is a worldwide supplier of forest seed centre and containerized nursery equipment. BCC develops, designs, produces and sales machines for forest seed handling. BCC s existing precision seeder can not handle seed that are tinier than 1 mm in diameter. With a growing market in countries with

Ulnar head replacement or head resection in patients with distal radioulnar arthritis: a prospective cohort study of clinical and patient-reported outcomes up to 2 years after surgery

Background and purpose — Traditional surgery forarthritis of the distal radioulnar joint (DRUJ), which typicallyinvolves resecting the ulnar head, is being increasingly challengedby newer techniques, such as prosthetic ulnar headreplacement. The aim of our prospective cohort study was toinvestigate the clinical and patient-reported functional results,up to 2 years postoperatively, among patients w

Impact of COVID-19 after lung transplantation : A retrospective multicenter comparison of clinical outcomes in Denmark and Sweden

Background: The coronavirus disease-2019 (COVID-19) pandemic posed pronounced challenges in the care of lung transplant (LTx) recipients. Global variations in containment strategies and the introduction of messenger ribonucleic acid (mRNA) vaccines have sparked extensive debate in both scientific and public arenas. Methods: This retrospective study compared outcomes among LTx recipients in Denmark