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Acute myeloid leukemia (AML) comprises a heterogeneous group of leukemias frequently defined by recurrent cytogenetic abnormalities, including rearrangements involving the core-binding factor (CBF) transcriptional complex. To better understand the genomic landscape of CBF-AMLs, we analyzed both pediatric (n = 87) and adult (n = 78) samples, including cases with RUNX1-RUNX1T1 (n = 85) or CBFB-MYH11
OBJECTIVES: The aim of this study was to investigate for the first time the association between body fat and risk of amyotrophic lateral sclerosis (ALS) with an appropriate prospective study design. METHODS: The EPIC (European Prospective Investigation into Cancer and Nutrition) study included 518,108 individuals recruited from the general population across 10 Western European countries. At recrui
Abstract in SpanishResumen: La tarea de la semiótica de la imagen no consiste solamente en determinar la especificidad de la imagen como signo, sino también en describir las particularidades de diferentes imágenes, como son, por ejemplo, el dibujo, la fotografía y la imagen de computadora. El presente texto describe, primero, el desarrollo del signo del tipo de laAbstract: The task of pictorial se
There are inconsistent and limited data available to assess the relationship between fat intake and risk of epithelial ovarian cancer (EOC). We examined the consumption of total fat, fat sources and fat subtypes in relation to risk of EOC and its major histologic subtypes in the European Prospective Investigation into Cancer and Nutrition which includes incident invasive (n=1095) and borderline (n
OBJECTIVETo study the association between dietary flavonoid and lignan intakes, and the risk of development of type 2 diabetes among European populations.RESEARCH DESIGN AND METHODSThe European Prospective Investigation into Cancer and Nutrition-InterAct case-cohort study included 12,403 incident type 2 diabetes cases and a stratified subcohort of 16,154 participants from among 340,234 participant
Acrylamide, classified in 1994 by IARC as 'probably carcinogenic' to humans, was discovered in 2002 in some heat-treated, carbohydrate-rich foods. The association between dietary acrylamide intake and epithelial ovarian cancer risk (EOC) has been previously studied in one case-control and three prospective cohort studies which obtained inconsistent results, and could not further examine histologic
The aims of this study were to investigate the association between smoking and incident type 2 diabetes, accounting for a large number of potential confounding factors, and to explore potential effect modifiers and intermediate factors.
BACKGROUND: In patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) and who are treated with direct oral anticoagulants (DOACs), dual antithrombotic treatment without aspirin is recommended. Evidence comparing P2Y 12 inhibitor strategies in this setting is limited. AIMS: This study aimed to compare outcomes with ticagrelor versus clopidogrel as part of
The new European X-ray Free-Electron Laser (European XFEL) is the first X-ray free-electron laser capable of delivering intense X-ray pulses with a megahertz interpulse spacing in a wavelength range suitable for atomic resolution structure determination. An outstanding but crucial question is whether the use of a pulse repetition rate nearly four orders of magnitude higher than previously possible
Introduction eHealth, defined by WHO as: “the transfer of health resources and healthcare by electronic means” are expected to increase communication between healthcare providers and patients and increase accessibility and patient participation in healthcare. The aim of this research programme is to: 1) develop a sustainable multidisciplinary environment for advancing, evaluating, and implementin
Snow cover plays a major role in the climate, hydrological and ecological systems of the Arctic and other regions through its influence on the surface energy balance (e.g. reflectivity), water balance (e.g. water storage and release), thermal regimes (e.g. insulation), vegetation and trace gas fluxes. Feedbacks to the climate system have global consequences. The livelihoods and well-being of Arcti
OBJECTIVE-Age at menopause is an important determinant of future health outcomes, but little is known about its relationship with type 2 diabetes. We examined the associations of menopausal age and reproductive life span (menopausal age minus menarcheal age) with diabetes risk. RESEARCH DESIGN AND METHODS-Data were obtained from the InterAct study, a prospective case-cohort study nested within the
Plasma adiponectin levels have previously been inversely associated with carotid intima-media thickness (IMT), a marker of subclinical atherosclerosis. In this study, we used a sex-stratified Mendelian randomization approach to investigate whether adiponectin has a causal protective influence on IMT.
A high-resolution study of the (e,e'p) reaction on Helium-4 was carried out at the Institut fuer Kernphysik in Mainz, Germany. The measurements were done in parallel kinematics (momentum transfer q=685 MeV/c, energy transfer omega=334 MeV) at different incident beam energies in order to enable the Rosenbluth separation of the longitudinal and transverse response functions.
ImportanceSyncope remains a diagnostic challenge despite advancements in testing and treatment. Cardiac syncope is an independent predictor of mortality and can be difficult to distinguish from other causes of transient loss of consciousness (TLOC).ObservationsThe cause of TLOC is often unclear, hospitalization criteria are ambiguous, diagnostic tests are frequently non-informative, and assessment
Universitets och högskolors arbete mot sexuella trakasserier (Rapport 2019:2) www.uhr.se Universitets och högskolors arbete mot sexuella trakasserier En undersökning på regeringens uppdrag Rapport 2019:2 Universitets och högskolors arbete mot sexuella trakasserier En undersökning på regeringens uppdrag Universitets och högskolors arbete mot sexuella trakasserier En undersökning på regeringens uppd
Negotiating the Climate Regime: The Process and Its Dynamics lukas LUMES Master’s Thesis 2004 Institutional Bargaining for the Climate Regime The Process and Its Dynamics Lukas Hsin-Chiang Hsu Graduate Institute of Diplomacy National Cheng-Chi University 116 Taipei, Taiwan E-mail:lukas866@hotmail.com Supervisor Karin Bäckstrand, PhD, Wallenberg Research Fellow Department of Political Science Lund
https://www.lumes.lu.se/sites/lumes.lu.se/files/hsu_hsin-chiang_lukas.pdf - 2026-07-24
