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Protein AA, the major repetitive protein subunit present in fibrils deposited in AA-amyloidosis, is an N-terminal cleavage product of a 104-amino acid precursor, serum amyloid A (SAA). Protein AA subspecies varying between 45 and 94 amino acids in length have been described. In this study it is shown that the different protein AA subspecies are not evenly distributed in amyloid deposits and that i
Based on concepts from quantum thermodynamics, the two-level system coupled to a single electromagneticmode is analyzed. Focusing on the case of detuning, where the mode frequency does not match the transitionfrequency, effective energies are derived for the levels and the photon energy. It is shown that these should be usedfor energy exchange with fermionic and bosonic reservoirs in the steady st
Molecular clocks estimate that diatom microalgae, one of Earth’s foremost primary producers, originated near the Triassic–Jurassic boundary (200 Ma), which is close in age to the earliest, generally accepted diatom fossils of the genus Pyxidicula. During an extensive search for Jurassic diatoms from twenty-five sites worldwide, three sites yielded microfossils initially recognized as diatoms. Afte
Wanting to help others and benefit society in one’s future career are examples of communal career goals. Raising these goals in youth should increase interest in HEED-occupations (Healthcare, Early Education, Domestic, and the Domestic fields) which are strongly gender-skewed and face labor shortage. Research has yet to find ways to increase communal career goals. In this study, we test the novel Wanting to help others and benefit society in one’s future career are examples of communal career goals. Raising these goals in youth should increaseinterest in HEED-occupations (Healthcare, Early Education, Domestic, and the Domestic fields) which are strongly gender-skewed and face labor shortage.Research has yet to find ways to increase communal career goals. In this study, we test the novel hy
PURPOSE: To determine the impact of the implementation of novel systemic regimens and locoregional treatment modalities on survival at population level in colorectal cancer (CRC) patients presenting with peritoneal metastases (PMs).METHODS: All consecutive CRC patients with synchronous PM (<3 months) between 1995 and 2014 were extracted from the Eindhoven area of the Netherlands Cancer Registry. T
Class actions in Sweden are not flourishing. This paper examines why the oldest class action regime in Scandinavia has not developed into anything more than a peripheral addition to the Swedish legal landscape, drawing on relevant procedural, political, and sociological insights. It is divided into two sections that (1) analyse the reform process in the 1990s and latest developments, including mai
Introduction. The ability to read and interpret different types of text can be significantly impacted by neuropsychiatric disabilities, which affect cognitive abilities. This paper explores and reviews previous studies within library and information science on neuropsychiatric disabilities in relation to reading practices. Method. Searches were performed in LISA and LISTA to identify research on Introduction. The ability to read and interpret different types of text can be significantly impacted by neuropsychiatric disabilities, which affect cognitive abilities. This paper explores and reviews previous studies within library and information science on neuropsychiatric disabilities in relation to reading practices. Method. Searches were performed in LISA and LISTA to identify research on
Starting from the premise that English negative modal contractions constitute partly variable patterns of associations that include both the preceding subject and the following verb infinitive, the study sets out to investigate distributional differences between can’t, shouldn’t, and won’t and their corresponding uncontracted parent forms. Given that some configurations are assumed to correlate wiStarting from the premise that English negative modal contractions constitute partly variable patterns of associations that include both the preceding subject and the following verb infinitive, the study sets out to investigate distributional differences between can’t, shouldn’t, and won’t and their corresponding uncontracted parent forms. Given that some configurations are assumed to correlate wi
The beam performance of the MAX II storage ring is described by computer simulations. The dynamic aperture reduction due to chromaticity correcting multipoles, higher order multipoles in quadrupoles and dipoles, alignment errors and energy deviations is calculated. The future operation of the storage ring with insertion devices is discussed. The results show that the MAX II storage ring will opera
For populists inside and outside of the German parliaments, Christianity is about belonging rather than believing. Yet identity politics are politics of exclusion that stifle democratic participation. In order to escape the anti-pluralist populist pattern, a starting point is to recognise Germany for what it is: a country whose citizens share multiple cultures and identities, all of which need to
Memory for pictures and words - perceptual and semantic factors in the picture superiority effect Georg Stenberg, Växjö University, Sweden Memory for pictures is known to surpass memory for corresponding concrete words, an effect often attributed to the more distinctive perceptual form of pictures. A consequence of this view is that picture superiority would not survive a transformation in which o
Most adaptive controllers do not assume any a priori knowledge about the process to be controlled. In most situations there is, however, some knowledge about the process. This knowledge should be used to improve the performance compared to the “black box” approach of earlier adaptive controllers. The a priori knowledge is in this paper used in the estimation of the process and also in the design o
The importance of nucleic acids in pure form for preparative and analytical perspectives, have increased constantly, demanding the development of new and more efficient methods for their recovery and isolation. This thesis describes a series of different innovative methods for recovery and purification of these biomolecules. In a general overview of a downstream processing, there are several criti
