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The blood-brain barrier (BBB) is a highly selective barrier separating the brain from the circulatory system. The physical barrier is built up by a monolayer of endothelial cells, which is the main component used for in vitro modeling. To create more physiologically relevant in vitro models, the field of organs-on-chips has recently been introduced, combining microfluidics and microengineering to
This thesis explores the connection between climate change and human rights from a legal perspective. Its starting point is the consideration of the plight of small island developing states (SIDS) in light of the adverse impacts of climate change on their territories and populations, such as the exacerbation of resource scarcity by climate change. In light of this, the thesis focuses on how water
Coiled coil is a simple and versatile type of protein fold. Proteins with this kind of structure play roles in a numerous kind of cellular processes, e.g. DNA repair, nucleoid organization, and cytoskeletal functions. Cytoskeletal intermediate filament (IF) proteins are an example of proteins containing large coiled coil domains. The eukaryotic cytoskeletal proteins tubulin and actin have well-stu
Managing water in urban areas is an ever increasingly complex challenge. Technology enables sustainable urban water management and with integrated smart metering solu- tions, massive amounts of water consumption data from the end users can be collected. However, the possibility of generating data from the end user holds no value in itself. It is with the use of data analysis the vast amount of the
This essay investigates the communicative elements video games in the RPG genre utilise in order to convey emotion through narrative, and the difference between older and newer games. The essay focuses on the execution and interplay of verbal and non-verbal communication of the linguistic and semiotic examined in four video games chosen from the Final Fantasy series. It quantitatively compares emp
This thesis presents the study of the K$^{0}_{s}$, $\Lambda$, and $\bar{\Lambda}$ production in pp collisions at $\sqrt{s}=13$~TeV recorded by the ALICE experiment at the LHC. The K$^{0}_{s}$, $\Lambda$, and $\bar{\Lambda}$ particles are reconstructed in the transverse momentum ($p_{\mathrm{T}}$) range of $1.0-12.0$~GeV/$c$ by using their \VNoll topology. The $p_{\mathrm{T}}$-spectra are studied a
Genomic rearrangements larger than 50 bp are called structural variants. As a group, they affect the phenotypic diversity among humans and have been associated with many human disorders including neurodevelopmental disorder and cancer. Recent advances in whole genome sequencing (WGS) technologies have made it possible to identify many more disease-causing genetic variants relevant in clinical diag
The ongoing human impact in form of deforestation, urbanization and intense agriculture is affecting the natural hydrology and our freshwater lakes negatively. Both eutrophication and brownification has seen to increase with the ongoing environmental change which can potentially have large impact on our freshwater ecosystems. Using a mesocosm experiment, this study investigates the individual and
Could the use of CSA practices stabilize the hunger crisis? Despite the general understanding that CSA practices increase farmers' food security, its resilience to climatic shocks is much less understood. To address this gap, this study analyzes the effect of three CSA practices: inorganic fertilization, intercropping and improved seeding on maize productivity in Ethiopia, Tanzania, and Uganda
Following the associated lockdown measures of the Covid-19 pandemic in 2020, the world economy started facing inflationary pressures from a surge in energy prices and supply chain disruptions at the end of 2021. Given the economic environment with low inflation and expansionary monetary policy following the Great Financial Crisis (GFC), central banks around the world have built up large balance sh
The current reality is that cities are losing green spaces rather than creating more of them, leading to many urban challenges. Urban nature-based solutions (NbS), through renaturing urban landscapes, are seen as a promising solution to help cities deal with climate change and build a better future for communities worldwide. In Europe, specifically, NbS is also seen as a way of boosting green innov
Marginalisation is present in youth education for sustainability. Reducing marginalisation in youth education for sustainability is crucial in the field of human ecology since it strives to understand environmental and social justice. This thesis explores the role of art in European youth education for sustainability and the potential of art to transform dominant Western industrial cultural assump
Icons are widely used throughout society; moreover, they play a significant role in computer user interfaces, frequently appearing on websites and applications. In many cases, they are used instead of text labels to make a user interface (UI) more universally understood, among other things. Since icons reside within the UI, they should adhere to UI design principles, such as ”reduce short-term mem
This thesis investigates five ex-inmates’ narratives on their pathways in and out of crime in Malta. In-depth interviews were conducted to generate their stories. Previous studies on criminal pathways tend to prioritise either the persistence or desistance path and present each path as a linear process. Within this context, the complexities of a criminal path and barriers towards desistance tend t
The purpose of this study is to analyze how Afghan evacuees have been constructed as belonging in Korea and what impacts might their status as ‘special contributors’ have for the future resettlement and integration of refugees. ‘Special contributor’ is a term used for the Afghan personnel and their families that worked with Korean governmental agencies in Afghanistan, and were evacuated upon the T
The long-lasting tradition of women that tackles roles within the military in the Kurdish free- dom movement is now, in recent years, beheld for better or for worse. This thesis will im- merse into the Kurdish women's agency in the Kurdish Women's Movement and their work of change for a more democratized Rojava by examing the source material "Stateless democracy with the Kurdish movem
This thesis examines how bisexuality get constructed as a distinct sexual orientation category through asylum determination processes in Sweden. With a theoretical focus on the interaction between notions of sexuality and national borders this study also investigates how the assessment of ‘sexual orientation’ asylum claims contribute to the regulation of the Swedish border. To investigate these tw
The spread of invasive alien species poses great risks for biodiversity, human health and economies. Impatiens glandulifera, an invasive alien plant which has been listed in The European list of Invasive Alien Species of Union concern, is widely spread in Sweden. Multiple studies have been made regarding the plant’s characteristics, spread and impacts on invaded areas. The purpose of this study i
The unicellular green alga of genus Chlamydomonas are well studied within the fields of photosynthesis and flagellar research. Although many molecular tools have been developed for use on Chlamydomonas, little research has been done on its ecology and population dynamics. Species within the genus are morphologically indistinguishable using light microscopy and as such a molecular method is necessa
