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Background: Video capsule endoscopy (VCE) is a noninvasive method enabling excellent visualization of the small bowel (SB) mucosa. The aim of this study was to examine the impact and safety of VCE performed in children and adolescents with suspected or established Crohn’s disease (CD). Methods: A total of 180 VCE examinations in 169 consecutive patients conducted in 2003–14 in a single center were
Open testicular wedge biopsy has electively been performed prior to completion of maintenance therapy for acute lymphoblastic leukemia. 25 boys during 6 years were included in this prospective study. Three boys developed testicular enlargement while on maintenance therapy and biopsies confirmed testicular leukemia. The remaining 22 boys were biopsied at termination of maintenance therapy. Occult t
The blood serum concentrations of creatinine and the low molecular weight proteins cystatin C, beta 2-microglobulin and retinol-binding protein were measured in 106 patients whose glomerular filtration rates were assessed by Cr-ethylenediaminetetraacetate (EDTA)-clearance determinations. The reciprocals of the serum concentrations of creatinine, cystatin C and beta 2-microglobulin were closely cor
Mycobacterium tuberculosis, the causative agent of human tuberculosis (TB), has surpassed HIV/AIDS as the leading cause of death from a single infectious agent. The increasing occurrence of drug-resistant strains has become a major challenge for health care systems and, in some cases, has rendered TB untreatable. However, the development of new TB drugs has been plagued with high failure rates and
Leonard Talmy’s influential binary motion event typology has encountered four main challenges: (a) additional language types; (b) extensive “type-internal” variation; (c) the role of other relevant form classes than verbs and “satellites;” and (d) alternative definitions of key semantic concepts like Motion, Path and Manner. After reviewing these issues, we show that the theory of Holistic Spatial
It is important to minimize transmission heat transfer losses through the building envelope when designing and building energy efficient buildings in heating dominated climates. In such a climate, a large part of the space heating demand is caused by transmission heat transfer losses through the building envelope. Calculations of these losses must be carried out in a correct way to ensure a proper
Activation of the contact system generates bradykinin from high-molecular-weight kininogen and has been suggested to participate in the pathophysiology of sepsis. To test this, we prospectively measured bradykinin and high-molecular-weight kininogen levels in a cohort of sepsis patients requiring intensive care. From 29 patients meeting criteria for sepsis or septic shock according to Sepsis-3, bl
Purpose: To investigate the main concerns associated with being a parent of a child with cataract and how the parents deal with these concerns. Design and method: Twenty-three parents; 6 mothers, 5 fathers and 6 couples with a child with cataract were included in this study. The parents included some with a personal experience of cataract and some without. Data was collected through 17 in-depth in
Migratory songbirds are guided by an endogenous programme during their first migration, encoding timing of migration, distance and direction. To successfully perform migration, birds have evolved phenotypic adaptations for flight, fuelling and navigation. Migratory distance in different species of birds is encoded as a period of expressed migratory restlessness, for which the length is correlated
A sensitivity analysis on test outcomes from the microscale combustion calorimeter was performed using flexible polyurethane foam as the sample material. Three input factors were investigated: sample preparation, heating rate and pyrolysis chamber atmosphere. The experiments were setup according to the principles of design of experiments and a full factorial design was implemented. In total, 39 ex
Hippocampal dysfunction plays a central role in neurodevelopmental disorders, resulting in severe impairment of cognitive abilities, including memory and learning. On this basis, developmental studies represent an important tool both to understanding the cellular and molecular phenomena underlying early hippocampal damage and to study possible therapeutic interventions, that may modify the progres
The Swedish Armed Forces have traditionally been exclusively male, and service in the cause of defending the country has until recently been the privilege of men. While the very first women entered the military 37 years ago, the military has so far failed to fully integrate women into the organization and promote gender equality. The object of this study is to probe servicewomen's meanings, identi
METHODS: Retrospective analysis of prospectively collected data 2010-2014 from the Swedish national dementia registry (SveDem) and the Swedish national stroke registry (Riksstroke). Patients with dementia who suffered an acute ischemic stroke (AIS) (n = 1,356) were compared with matched non-dementia AIS patients (n = 6,755). Outcomes included length of stay in a stroke unit, total length of hospit
Spectral analysis as well as parametric identification techniques have been applied to data from boiling water reactor noise measurements to estimate the process dynamics. Three different parametric model structures were tried. Least squares and maximum likelihood methods were tried to estimate the parameters of the models. Low order models were obtained in most cases.The results show the difficul
Background: To examine risk of severe perineal trauma among nulliparous women and those undergoing vaginal birth after cesarean delivery (VBAC). Methods: This is a population-based cohort study of all births to women with their two first consecutive singleton pregnancies in Stockholm-Gotland Sweden between 2008 and 2014. Risk of severe perineal trauma was compared between nulliparous women and tho
This thesis addresses the corporate sustainability process and different tools to assist the process of generating corporate strategies towards sustainability in the energy sector. The focus of the research was in backcasting approaches. The main outcome of the work is a framework for corporate sustainability for the energy sector. The framework is constructed around a three step strategic plannin
Abstract Background. Dosimetry in radionuclide therapy estimates delivered absorbed doses to tumours and ensures that absorbed dose levels to normal organs are below tolerance levels. One procedure is to determine time-activity curves in volumes-of-interests from which the absorbed dose is estimated using SPECT with appropriate corrections for attenuation, scatter and collimator response. From cor
BACKGROUND: Sphingolipids (SL), in particular sphingomyelin (SM) are important components of milk fat polar lipids. Dietary SM inhibits cholesterol absorption in rats (Nyberg et al. J Nutr Biochem. 2000) and SLs decrease both cholesterol and TG concentrations in lipid- and cholesterol fed APOE*3Leiden mice (Duivenvoorden et al. Am J Clin Nutr. 2006). This human study examines effects of a butter m
Current therapy for haemophilia A is guided by severity of the disease, which in turn is best reflected in patients' endogenous factor VIII activity levels. For patients with severe haemophilia (particularly children), prophylaxis with continuous routine factor replacement has become standard of care in developed countries and is gradually becoming the standard of care in developing countries. The
