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Polyphosphoinositides, the different phosphorylated variants of the phospholipid phosphatidylinositol (PtdIns), are used in a wide array of intracellular mechanisms in eukaryotic cells. The phosphorylation of PtdIns at carbon D4, catalyzed by phosphatidylinositol 4-kinase, is an important step in the synthesis of several of these molecules. The presence of different isoenzymes of PtdIns 4-kinase i

The sun and its heat are two of the most universal symbols known to humanity, yet their supposed meanings vary greatly. The sun can be thought of as a giver of life, but its hot and scorching rays can also be associated with drought and the powers of destruction. The present study concerns the latter view of the sun and related ideas as reflected in the Hebrew Bible and the cuneiform alphabetic te

Abstract is not available

Today many methods are available for gas turbine flow path analysis. Some of them are very simple but yet very useful, since they give an indication of the compressor capacity with almost no calculation effort. The state of the art today is the heat and mass balance models (HMB), which are more sophisticated. This paper presents a general overview of these methods, including the most recent trend,

The principles for today's international refugee policies were laid down in the years following World War II, with the creation of the UNHCR and the establishment of an international refugee convention. These years, which were the central phase in the development of a new refugee regime, are the topic. The refugee question is set in an East-West perspective. The rethoric of refugee policies is con

The lean stability limit of a prototype syngas burner is investigated. The burner is a three sector system, consisting of a separate igniter, stabilizer and Main burner. The ignition sector, Rich-Pilot-Lean (RPL), can be operated with both rich or lean equivalence values, and serves to ignite the Pilot sector which stabilizes the Main combustion sector. The RPL and Main sectors are fully premixed,

Heat transfer losses are one of the largest loss contributions in a modern internal combustion engine. The aim of this study is to evaluate the contribution of the piston bowl type and swirl ratio to heat losses and performance. A commercial CFD tool is used to carry out simulations of four different piston bowl geometries, at three engine loads with two different swirl ratios at each load point.

Robots interacting with other agents in rich information landscapes and complex dynamic physical environments require sophisticated and robust concept and knowledge management capabilities if they are to solve problems, communicate, learn and exhibit intelligent behaviours. In this paper we describe how conceptual spaces provide a powerful substrate upon which to build effective concept and knowle

A swirl stabilized flame has been studied numerically using Large Eddy Simulation. The response of the flame to a large swirl number modulation has as been determined. Decreasing the swirl number moderately does not destabilize the flame. Decreasing further the swirl number induces a transition from stabilized to a jet flame with increase in the flame fluctuations. Increasing back the swirl restor

Most animals use eyes to guide their behaviour. Analysing, and understanding, visually guided behaviours gets more complicated the more advanced the animal gets. Box jellyfish provide a relatively simple system for understanding visually guided behaviours. They have a limited nervous system, but they also possess a visual system that is quite impressive for a jellyfish. Box jellyfish have 24 eyes