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Recently, work conducted by the European Commission’s Joint Research Centre demonstrated that Ireland had the highest prevalence of loneliness of all European countries. Given the range of adverse physical and psychological consequences associated with loneliness, it is vital to ask why Ireland is experiencing such high prevalence. Here, we discuss potential contributing factors, including: Irelan
The ways in which we experience life through, with and around media constitutes creative practices in our daily routines. However, media use is in part associated with harmful effects, for example television viewing amongst children and young people (Livingstone 2009). Discourses around digital games have been echoing the same type of concerns, becoming one of the focal points of these struggles i
Agonistic CD40 antibodies activate dendritic cells and can expand and activate tumor-specific T cells. Our purpose was to assess the CD40 agonistic antibody ADC-1013 in the clinical setting including intratumoral administration since preclinical studies have indicated that intratumoral is better than intravenous administration. A Phase I, open label, multicenter study was conducted in patients wit
The integration of proton exchange membrane fuel cells (PEMFCs) in heavy-duty vehicles and other demanding applications, such as aviation, would be simplified if the stacks could operate above 100 °C instead of the traditional low temperature (LT, up to 80 °C), thereby allowing a reduction in cooling system in size and power. This review offers a comprehensive compilation of experimental studies r
Self-efficacy is tightly intertwined with person-centered care and correlates with engaging in self-care behaviors, an important part of hypertension treatment. Evidence indicates that e-Health-based self-management interventions could increase self-efficacy. The objectives of this study were to investigate whether an intervention with a person-centered approach supported by e-Health technology ca
• Purpose: To assess whether distal radius fracture (DRF) malunion is associated with greater patient-reported disability. • Methods: We searched PubMed, EMBASE, and Cochrane databases up to 21 May 2023. Two reviewers independently screened retrieved titles/abstracts and assessed the full text of potentially eligible articles to identify cohort studies and randomized controlled trials reporting ou
We explore how the Resilient Urban Food Systems (RUFS) project applied a theory of change approach to raise awareness of the importance of smallholder farmers and to bring them into decision making processes, as key players working towards a sustainable and resilient food system in Kasese Municipality and Mbale City in Uganda. Critical inputs from using a theory of change approach included: consta
The virtual reconstruction of the archaeological landscape is a very complex process including in a virtual ecosystem many kinds of data, activities, according to a multidisciplinary approach. This system of relations, interactions and behaviors assumes perceptive, cultural, psychological and relevance. The virtual environment and archaeological structures, as they are today, can be reconstructed
This study showcases an integrative mass spectrometry-based strategy combining systems antigenomics and systems serology to characterize human antibodies in clinical samples. This strategy involves using antibodies circulating in plasma to affinity-enrich antigenic proteins in biochemically fractionated pools of bacterial proteins, followed by their identification and quantification using mass spe
Identifying potential moisture damage is crucial for maintenance practices and assurance of well-being of occupants. However, due to limited information availability and standardization, assessing damage prevalence on the building stock scale remains understudied. By combining investigation records and building databases, this study leverages data analytic techniques and machine learning modeling
Background: Many women consume alcohol while pregnant before they are aware of the pregnancy, raising concerns about potential harms to the developing fetus. Official guidelines in the United Kingdom recommend abstinence throughout pregnancy, and many women turn to online forums for reassurance and information. However, online forums can also become a source of misinformation, potentially increasi
Intentional vocabulary learning through tasks with an explicit vocabulary focus is essential for L2 learning (e.g., Laufer, 2005; Nation, 2007, 2022; Schmitt & Schmitt, 2020). Yet, research suggests that in EFL classrooms in Sweden, there tends to be a reliance on incidental learning of vocabulary rather than intentional learning (D. Bergström, 2023). Studies(Eriksson, 2023; Warnby, 2023) also
Theoretical work suggests that reinforcement can cause the strengthening of prezygotic isolation in sympatry by mitigating the costs of maladaptive hybridization. However, only a handful of studies have simultaneously tested multiple predictions of this theory in natural populations. We investigated reinforcement in a mottled hybrid zone between the damselflies Ischnura elegans and Ischnura graell
Today's petrochemical industry relies on fossil hydrocarbons, not only for energy purposes but also as feedstock. This use of fossil materials is being challenged by the European Union's target to achieve climate neutrality by 2050. The most affected region in Europe is the cross-border region between Antwerp, Rotterdam and the Rhine-Ruhr area in western Germany, an interconnected petrochemical me
This study evaluated the transition rates from schizotypal disorder to non-affective psychosis and schizophrenia in particular aiming to identify clinical and demographic factors associated with these transitions. We conducted a nationwide cohort study using data from the Swedish Patient Register and the Cause of Death Register, including patients aged 18 and older diagnosed with schizotypal disor
Purpose: From an active ageing perspective, investigating how adults use apps and wearables for health purposes might improve well-being strategies supported by widely adopted technologies. This study investigated adults’ perceptions of using apps and wearables for health purposes. Methods: A qualitative interview study was conducted. Adults (+18) using an app/wearable to monitor at least one heal
