Filetype
The use of hyperbaric oxygen therapy (HBO) in the treatment of certain types of diabetic foot ulcers (DFU) has been the topic of much debate and disagreement over the last several decades. In this review, the evidence for its use is presented and discussed by two experts in DFU management. Whereas some randomized controlled trials suggest that HBO may speed the healing of certain ischaemic or neur
The HUSH complex represses retroviruses, transposons and genes to maintain the integrity of vertebrate genomes. HUSH regulates deposition of the epigenetic mark H3K9me3, but how its three core subunits — TASOR, MPP8 and Periphilin — contribute to assembly and targeting of the complex remains unknown. Here, we define the biochemical basis of HUSH assembly and find that its modular architecture rese
Background: Conduct disorder (CD), a serious behavioral and emotional disorder in childhood and adolescence, characterized by disruptive behavior and breaking societal rules. Studies have explored the overlap of CD with neurodevelopmental problems (NDP). The somatic health of children with NDP has been investigated; however, the prevalence of these problems in children with CD has not been suffici
Introduction: The benefits of simulation-based medical training are well described. The most effective way to plant and scale simulation training in rural locations remains undescribed. We sought to plant simulation training programmes for anaesthesia emergencies in two rural Indian hospitals. Methods: Two Indian consultant anaesthetists without experience in medical simulation underwent a 3-day c
Objective. Patients with ANCA-associated vasculitides (AAV) exhibit higher rates of malignancy than the general population. We assessed whether the cancer risk is increased in a well-characterized population-based cohort of AAV in southern Sweden, followed for a median time of 8 years. Methods. With case record review, the outcomes and malignancy development in a cohort of 195 patients with AAV [g
Research Question/Issue: On the basis of a dynamic interrelation between the assumptions of agency theory and stewardship theory, this study seeks to make sense of disobedience at the highest corporate level. Departing from a processual view in order to better understand how loyalty plays a critical role in the relationships between a CEO and his/her principal, we propose a conceptualization of th
Endovascular recanalization of occluded venous femoropopliteal bypass grafts is widely used because of easy access. This case report describes pseudoaneurysm developing 4 weeks after endovascular recanalization of an occluded in situ venous femoropopliteal graft. The patient was treated for a popliteal aneurysm with a venous femoropopliteal bypass graft, which subsequently occluded. Four weeks aft
Purpose: Disability affects upwards of one billion people worldwide, the majority of whom live in low- and middle-income countries. Based on survey data from Bangladesh, the aim of the study is to contribute to an improved understanding of the experiences of people with disabilities in terms of discrimination, health, and sociodemographic indicators. Method: A descriptive analysis of data is prese
Objective: To study if comatose cardiac arrest patients can be assessed with a reduced number of EEG electrodes. Methods: 110 routine EEGs from 67 consecutive patients, including both hypothermic and normothermic EEGs were retrospectively assessed by three blinded EEG-experts using two different electrode montages. A standard 19-electrode-montage was compared to the reduced version of the same EEG
The sustainability of complex resource systems, such as the food, water, and energy (FWE) nexus, is increasingly threatened by climate change impacts, expanding populations, urbanization, and economic instability. However, while research on the topic has burgeoned, studies focused on solution development and implementation, especially at the urban level, have lagged behind. Against this background
In the present review, we highlight the possible “extra-immunological” effects of maternal immunoglobulins (Ig) transferred to the blood circulation of offspring, either via the placenta before birth or via the colostrum/milk across the gut after birth in different mammalian species. Using the newborn pig as a model, since they are naturally born agammaglobulinemic, intravenously (i.v.) infused pu
In the mixed-valence manganites, a near-infrared laser typically melts the orbital and spin order simultaneously, corresponding to the photoinduced d1d0→d0d1 excitations in the Mott-Hubbard bands of manganese. Here, we use ultrafast methods-both femtosecond resonant X-ray diffraction and optical reflectivity-to demonstrate that the orbital response in the layered manganite Nd1-xSr1+xMnO4(x=2/3) do
With the rapid development of short-pulse intense laser sources, studies of matter under extreme irradiation conditions enter further unexplored regimes. In addition, an application of X-ray Free-Electron Lasers (XFELs) delivering intense femtosecond X-ray pulses, allows to investigate sample evolution in IR pump - X-ray probe experiments with an unprecedented time resolution. Here we present a de
We present a reflector antenna system using a circular polarization selective surface (CPSS) to realize a circular polarization (CP) equivalent to the widely used linear polarization (LP) gridded or dual-gridded reflector (DGR). The CPSS is realized by a multilayer stack of non-resonant anisotropic meander line surfaces, achieving a very wide bandwidth. The CPSS reflection and transmission dyadics
Vacuum cleaner motor is an air cooled single-phase induction motor with impeller. Its compact design can result in more than 2 kW of input power per 1 kg of mass. It can operate only if an air flow is cooling the motor; otherwise it is overheated and destroyed. A large production volume of a vacuum cleaner motor classifies it as a mass production product. In the past its development has been mostl
The tryptophan to kynurenine ratio (Trp/Kyn) has been proposed as a cancer biomarker. Non-invasive topical sampling of Trp/Kyn can therefore serve as a promising concept for skin cancer diagnostics. By performing in vitro pig skin permeability studies, we conclude that non-invasive topical sampling of Trp and Kyn is feasible. We explore the influence of different experimental conditions, which are
In this work, we present a detailed investigation of the optical properties of hybrid perovskite building blocks, [PbI2+n]n−, that form in solutions of CH3NH3PbI3 and PbI2. The absorbance, photoluminescence (PL) and photoluminescence excitation (PLE) spectra of CH3NH3PbI3 and PbI2 solutions were measured in various solvents and a broad concentration range. Both CH3NH3PbI3 and PbI2 solutions exhibi
The hole transporting medium in solid-state dye-sensitized solar cells can be utilized to harvest sunlight. Herein we demonstrate that a triphenylamine-based dye, used as hole-transporting medium, contributes to the photocurrent in a squaraine-sensitized solid-state dye-sensitized solar cell. Steady-state photoluminescence measurements have been used to distinguish between electron transfer and en
Inspired by the contemporary Danish philosopher Dorthe Jørgensen, this article engages in a re-reading of Peter Kemp’s 1973 dissertation Théorie de l’engagement with a view to exploring its persisting theological value. After briefly revisiting its main argument, I turn in the following section to a discussion of its way of relating phenomenology and theology in terms of short-comings as well as p
