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Urokinase, a serine protease, catalyzes the conversion of plasminogen to plasmin, which is responsible for dissolution of clots in blood vessels. It is an important drug for treatment of thromboembolic disease. Production of urokinase by mammalian cell culture has the following important steps: synthesis, regulation and secretion. Production and accumulation of this product in a bioreactor is a re
A resonant tunneling permeable base transistor has been realized experimentally by overgrowing a tungsten grating placed in direct vicinity to a double barrier heterostructure. In this way, we can directly modulate the tunneling current via an embedded gate. Since the quality of the overgrown interface is critical, special attention is paid to this issue, and the effect of different wet etchants p
BACKGROUND: The diagnostic utility of magnetic resonance imaging in dementia workups has increased recently. The basic use is to exclude space-occupying processes in the brain. However, magnetic resonance imaging offers major opportunities for studying atrophy of specific brain areas. A great interest has been put in whether atrophy in the medial temporal lobe can serve as an early diagnostic mark
This paper investigates a variety of forms of management control in a large management consultancy company. The very high level of compliance with corporate objectives among employees is highlighted and singled out as a phenomenon worth exploring. The company exhibits a rich variety of various formal control devices focusing on financial issues as well as human resources. The paper shows that thes
A shift in business thinking from selling products to providing service solutions to customer needs is becoming noticeable. It is driven by increasing competition and the need to identify new profit centres for producers of mature products. This paper identifies a new product group that could be interesting from the product-service system perspective - baby prams. The study presents a new business
Organic food standardization is an increasingly important strategy for dealing with consumer concerns about the environment, animal welfare, health, and the economic structure of food production. But the ways in which this consumer-oriented strategy is introduced, organized, and debated vary considerably across countries. In Sweden, a nongovernmental organization [KRAV (Association for Control of
Background: Achondroplasia is a skeletal dysplasia with extreme, disproportionate, short stature. Aim: In a 5-y growth hormone (GH) treatment study including 1 y without treatment, we investigated growth and body proportion response in 35 children with achondroplasia. Methods: Patients were randomized to either 0.1 IU/kg (n=18) or 0.2 IU/kg (n=17) per day. GH treatment was interrupted for 12 mo af
The Swedish sound string /at/ (graphically: att) is associated with two grammatical functions: a) (part of) a subordinate conjunction and b) as an infinitive marker. Previous studies connect final lengthening and pauses with prosodic and syntactic boundaries in spoken discourse. Following these findings, this pilot study, with 5 short spontaneous discourses from 3 male speakers shows a correlation
We present a systematic study of different reconstructions obtained after deposition of Au on the (root 3 x root 3)- R30 degrees- 4H- SiC( 0001) surface. For 1-2 monolayers ( ML) Au and annealing temperature T-anneal similar to 675 degrees C, a 3 x 3 reconstruction was observed. For 4 ML Au and T-anneal similar to 650 degrees C, a ( 2 root 3 x 2 root 3)- R30 degrees. reconstruction appeared, while
OBJECTIVES. The authors studied complications of transpedicular stabilization methods. SUMMARY OF BACKGROUND DATA. One hundred and sixty-three consecutive transpedicular stabilization procedures were performed between January 1987 and December 1991. The indications for stabilization were trauma (33 cases), metastatic spinal disorder (30 cases), spinal stenosis (33 cases), spondylolisthesis (27 cas
Ultraviolet (UV) radiation is harmful to all life, and the ongoing depletion of the ozone layer is likely to affect interactions among both terrestrial and aquatic organisms. Some organisms have evolved adaptations to reduce radiation damage, such as the various types of protective pigmentation of freshwater zooplankton. However, strong pigmentation also increases vulnerability to visually hunting
Current internal radiation dosimetry models for the small intestine, and for most walled organs, lack the ability to account for the activity uptake in the intestinal wall. In existing models the cross-dose from nearby loops of the small intestine is not taken into consideration. The aim of this investigation was to develop a general model for calculating the absorbed dose to the radiation-sensiti
In the study of economic-geographic structures, the shifting focus from the national state to the city and its region has highlighted the lack of reliable interurban data sets. The abundance of usable data sets on international structures and ?ows has no counterpart when studying interurban relations, which makes it hard to draw any extensive conclusions regarding the structure of world city netwo
New magnetic moments presented here allow stringent tests of the truncated shell model calculations performed in the region below the N = 50 neutron shell. The experimental g-factors for selected medium-spin yrast states in Mo-90 were determined via the IMPAD technique using the (Ni(Cl,3p))-Ni-58-Cl-35 reaction. The results of g(5-, 2549 keV) = +1.10 +/- 0.28, g(11-, 4842 keV) = +0.42 +/- 0.13 and
