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This work presents a photodissociation study of the diamondoid adamantane using extreme ultraviolet femtosecond pulses. The fragmentation dynamics of the dication is unraveled by the use of advanced ion and electron spectroscopy giving access to the dissociation channels as well as their energetics. To get insight into the fragmentation dynamics, we use a theoretical approach combining potential e

Background: Research is needed on how to optimize the return-to-work process for persons with mental health problems.Objective: To develop a model that explains how employer and rehabilitation professional mental health literacy may influence strategies used in the return-to-work of persons with mental health problems.Methods: A grounded theory study design was used to collect and analyse intervie

The common human pathogen Group A Streptococcus (GAS) causes superficial as well as invasive, life-threatening diseases. An increase in the occurrence of invasive GAS infection by strains of the M1 and M89 serotypes has been correlated with increased expression of the genetically and functionally linked virulence factors streptolysin O (SLO) and β-NAD+-glycohydrolase (NADase). NADase affects host

A new strategy towards tubular hydrogen-bonded polymers based on the self-assembly of isocytosine tautomers in orthogonal directions is proposed and experimentally verified, including by 1H fast magic-angle spinning (MAS) solid-state NMR. The molecular tubes obtained possess large internal diameter and tailor-made outer functionalities rendering them potential candidates for a number of applicatio

Objective: To perform genetic linkage analysis in a family affected with ALS and frontotemporal dementia (FTD). Methods: The authors performed a genome-wide linkage analysis of a four-generation, 50-member Scandinavian family in which five individuals were diagnosed with ALS and nine with FTD. Linkage calculations assuming autosomal dominant inheritance of a single neurodegenerative disease manife

Organized human papillomavirus (HPV) vaccination was introduced in Sweden in 2012. On-demand vaccination was in effect from 2006 to 2011. We followed the HPV prevalences in Southern Sweden from 2008 to 2013.

Objective: To compare guidelines from the Royal College of Obstetricians and Gynaecologists (RCOG) based on the Risk of Malignancy Index (RMI) with a protocol based on logistic regression model LR2 developed by the International Ovarian Tumour Analysis (IOTA) group for triaging women with an ovarian mass as low, moderate, or high risk of malignancy. Design and setting Observational diagnostic stud

Genetic susceptibility to PBC can, at least in part, be ascribed to the major histocompatibility complex. The relevance of immunogenetic markers for the clinical presentation and course, however, is unclear. Thus, the aim of this study was to investigate the contribution of HLA class II genes to susceptibility, clinical presentation and course of disease in PBC patients. HLA genotyping for HLA-DRB

We report experimental measurements of high-order harmonic spectra generated in Ar using a carrier-envelope-offset (CEO) stabilized 12 fs, 800 nm laser field and a fraction (less than 10%) of its second harmonic. Additional spectral peaks are observed between the harmonic peaks, which are due to interferences between multiple pulses in the train. The position of these peaks varies with the CEO and

To overcome the limited treatment depth of superficial photodynamic therapy we investigate interstitial light delivery. In the present work the treatment light was delivered using a system in which three or six clear-cut fibers were placed in direct contact with the tumor area. This placement was thought to represent a step toward general purpose interstitial PDT. Twelve nodular basal cell carcino

Popular Abstract in Swedish Avhandlingen berör membranbaserade tekniker för provupparbetning, vilket enkelt uttryckt innebär att använda membran för att ”skilja agnarna från vetet”. De membran som använts kan designas för att vara selektivt genomsläppliga, d.vs. släppa igenom vissa molekyler och inte andra. Denna selektivitet behöver inte vara baserad på molekylstorlek, tvärtom styrs den mer av moComplex biological and environmental samples require a high degree of selectivity in order to determine components therein. Sensitivity measures, such as analyte pre-concentration are often required for assessing composition quantitatively. Use of membranes and especially non-porous membranes for extraction purposes offers in many cases the desired measure of selectivity and sensitivity for trace

Popular Abstract in Swedish Ett varmare klimat ökar generellt risken för angrepp av skadeinsekter på jordbruksgrödor, och många skadeinsekter förväntas sprida sig norrut. Den här avhandlingen fokuserar på hur ett varmare klimat kan påverka koloradoskalbaggen, en allvarlig skadegörare i potatisodlingar. Koloradoskalbaggen kom från Mexiko till Europa i början av 1900-talet, och har sedan dess spridiEuropean agriculture is facing the challenge of managing the impact of climate change on food security. Agriculture in a northern temperate climate is likely to benefit from higher temperature and longer growing season while, in the south, crop productivity is likely to decline. Such changes in climate could also affect the population dynamics of insect pests. The Colorado potato beetle (CPB) is o

Synthesis of metal-oxide nanoparticles and utilization of these particles as gate materials for field-effect sensor devices is reported. Improved selectivity to specific gases is expected by modulating the size of the oxide nanoparticles or impregnating them with catalytic metals. Another objective is to improve the long-term thermal stability of the sensors, since the metal loaded nanoparticles m

Under det senaste decenniet har hemlösheten rönt stor uppmärksamhet, men samtidigt är kunskapen otillräcklig om de processer som leder in i respektive ut ur hemlöshet samt om olika åtgärders effekter. Syftet med denna antologi är att ge en bred och allsidig bild av svensk hemlöshet utifrån olika perspektiv och förklaringsmodeller samt att ge några internationella utblickar. Författarna är forskare

Klimatförändringarna gör världen successivt varmare, förändrar nederbördsmönster, höjer havsytenivån, med mera. Klimatet har redan förändrats och i alla fall en viss fortsatt förändring är oundviklig på grund av tidigare och pågående växthusgasutsläpp. Hur stora klimatförändringarna blir på sikt beror i första hand på beslut om och åtgärder för att minska vår klimatpåverkan, det vill säga utsläpp

We have used transmission electron microscopy to determine the morphology of InP Stranski–Krastanow islands in GaInP, grown by metalorganic chemical vapor deposition at 580 °C. We investigated both capped and uncapped islands. It was found that the fully developed islands have the principal shape of truncated pyramids with a hexagonal base both before and after overgrowth. The planes defining the

Somatic mutations in cancer genomes are caused by multiple mutational processes, each of which generates a characteristic mutational signature1. Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium2 of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA), we characterized mutational signatures using 84,729,690 somatic mutations from 4,645 who

This report looks at different methods of active teaching and learning and the application of these methods at the partner universities of the SPIDER project. Different methods of on-campus and online teaching are presented and reports on experiences in their application at the partner universities are discussed. In combination with the results from Intellectual Output (IO) 4, this results in best

Photo-generated charge carrier dynamics in Ruddlesden-Popper 2D perovskites with linear (n-BA) and branched (iso-BA) butylamine as spacing cations have been studied by using transient absorption and time-resolved photoluminescence spectroscopies. Both n-BA and iso-BA perovskites consist of mixed-phase 2D quantum wells with various layer thicknesses, where the photo-generated charges undergo inter-