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PACAP and airway regulation with special reference to smooth muscle and neutrophils

Popular Abstract in Swedish Andningsvägarna kan schematiskt uppdelas i en övre och nedre del där den övre består av näsa, bihålor, (mellanöra) och struphuvud och den nedre av luftstrupe, luftrör samt alveoler. Sjukdomar i andningsvägarna, såsom astma och olika allergiska tillstånd, är vanligt förekommande, men mekanismerna bakom deras uppkomst och utveckling är ofullständigt klarlagda. NeuropeptidThe investigations focus on the neuropeptidepituitary adenylate cyclase-activating peptide and its effects on airway regulation, with emphasis on smooth muscle relaxation and neutrophil activation and migration. In the nasal mucosa, PACAP-containing nerve fibers were localized invascular smooth muscle and close to seromucous glands. In the lung, PACAP-containing nerve fibers were found close to se

Developing knee joint osteoarthritis: Clinical, radiographical and biochemical features.

Popular Abstract in Swedish Knäledssmärtor och knäledsartros: kliniska, röntgenologiska och biokemiska undersökningar under tidig artrosutveckling Långdragna knäsmärtor (dagligen i mer än 3 månader) förekommer hos 15 % av personer i åldern 35-54 år. Det visar vår undersökning av befolkningen i Laholms kommun i sydvästra Sverige. En orsak till långdragna knäsmärtor kan vara artros (s.k. broskförThe aim of this project was to study clinical, radiographical and biochemical features of developing, symptomatic knee osteoarthritis (OA) prospectively in individuals aged 35-54 from the general population. A questionnaire to a random sample of 2 000 individuals in the district of Laholm, Sweden, identified 279 individuals (15% of the population) with chronic (>3 months) knee pain. Of these, 204

"Man kan bli bättre om man vet vad bättre är!" : En studie kring effektivitetsbegreppet som en samhällelig grundbult

Popular Abstract in Swedish I allt större grad har effektivitetsbegreppet kommit i fokus i samhällsomvandlingen. I huvudsak utgår vi från att effektivitet i första hand är liktydigt med ekonomisk effektivitet. Existensen av en slags övergripande, ekonomisk "rationalitet", tas för given och har närmast karaktären av naturlag eller central, samhällelig grundbult. Under det senaste decenniet har omfaThe study takes as its starting point the far-reaching organizational changes that have occurred within the public sector in Sweden, particularly the public health care sector, during the last decade. The aim of achieving efficacy has been an important driving force in these processes, which often concern mergers or reductions in personnel that are regarded as a route to success. Paradoxically, Sw

Financing of Small and Cottage Industries in Bangladesh by Islamic Banks: An Institutional-Network Approach.

Popular Abstract in Swedish I denna studie utvecklas olika begrepp och samband mellan dessa begrepp (en teoretisk referensram) för att beskriva och förklara relationer mellan långivare och låntagare i landsbygdsbaserade små företag och de förhållanden i omgivningen som påverkar dessa relationer. Referensramen tillämpas på Bangladesh betonar särskilt den roll som islamska banker har. Teorier från iThis study is characterized by its development of an analytical framework for describing and explaining the lender-borrower financing relationships of rural-based small and cottage industries by including contextual conditions. It applies this framework to the socio- environmental conditions of Bangladesh with special emphasis on the role of Islamic banks. A theoretical framework based on institu

Konstitutionellt kritiskt dömande. Förändringen av nordiska domares attityder under två sekel

Popular Abstract in Swedish Under senare år har de högsta domstolarna i Norden i ett antal uppmärksammade avgöranden åsidosatt lagar, som stått i strid med respektive lands grundlag eller med EKMR. En omdebatterad fråga är om domstolarna har gått för långt – eller om de har väntat för länge med att ta på sig denna uppgift. I denna bok sätts de nordiska domarnas uppgift att kritiskt granska lagarsIn recent years, the supreme courts in the Nordic countries have set aside statutes as contrary to the constitution of the country or to the ECHR. A much debated question is whether the courts have gone too far – or if they have waited too long to take on this task. In this dissertation, the task of Nordic judges to critically examine the compatibility of legislation with constitutional norms is

Biological and air monitoring of exposure to isocyanates

Popular Abstract in Swedish På de allra flesta arbetsplatser utsätts arbetstagarna för risker, och de kemiska hälsoriskerna utgör en omfattande del av dessa. Till exempel är det många som får astma orsakad av exponeringar i arbetsmiljön. En vanlig orsak till yrkesrelaterade luftvägsbesvär är exponering för isocyanater. Isocyanater är små reaktiva (instabila) ämnen som används i polymerindustrin föExposure to isocyanates may induce disorders in the airways of workers. Therefore, application, development and validation of methods for exposure assessment is of great importance. In the present study, we have determined the personal air and biomarker levels of isocyanates for a group of occupationally exposed workers (n=170) in different types of industrial processes. Also, the biomarker levels

Performance Analysis of a Countercurrent Flow Heat Exchanger Placed on the Truck Compartment Roof

Due to the increasing power requirement and the limited available space in vehicles, placing the heat exchanger at the roof or the underbody of vehicles might increase the possibility to handle the cooling requirement. A new configuration of the heat exchanger has to be developed to accommodate with the position change. In this paper, a countercurrent heat exchanger is developed for position on th

Fungal Lectins. Molecular structure and function of a member of a novel lectin family.

Popular Abstract in Swedish En typisk egenskap för de flesta proteiner är att de kan binda specifikt och reversibelt till olika ämnen. Välkända exempel är enzymer som kan binda till olika substrat och inhibitorer samt antikroppar som binder till antigen. Under min tid som doktorand vid avdelningen för mikrobiologisk ekologi vid Lunds universitet har jag studerat en grupp av proteiner i svamp som kLectins defined as non-enzyme, non-immunoglobulin carbohydrate binding proteins, have been found in a wide variety of viruses, bacteria, fungi, plants and animals. Although lectins have been purified from more than 60 different species of fungi, the structure and biological functions of these proteins are not well known. I examined the molecular structure of a lectin (designated AOL) isolated from

List sequence MAP decoding

A list sequence (LS) maximum a posteriori probability (MAP) decoding algorithm for convolutional codes, that takes into account bitwise a priori probabilities and produces a rank ordered list of [script L] sequence MAP estimates, can be obtained by modification of the metric increments of the serial list Viterbi algorithm. In this paper, we study the performance of LS-MAP decoding with genie-assis

Symmetry of Two-Terminal Nonlinear Electric Conduction

The well-established symmetry relations for linear transport phenomena cannot, in general, be applied in the nonlinear regime. Here we propose a set of symmetry relations with respect to bias voltage and magnetic field for the nonlinear conductance of two-terminal electric conductors. We experimentally confirm these relations using phase-coherent, semiconductor quantum dots.

Living donors - How far can we proceed? A brief report on a Swedish interview study

In Sweden "anonymous living donation'' (ALD) has recently been performed but is still under evaluation. We considered it important to learn more about the thoughts of the volunteers for such a donation. Five persons out of ten people who had volunteered to donate anonymously at the transplant unit at Malmo University Hospital were interviewed. The main reason for the wish to donate was the possibi

Pathogenesis of autoimmune diseases: antibodies against transglutaminase, peptidylarginine deiminase and protein-bound citrulline in primary Sjögren's syndrome, multiple sclerosis and Alzheimer's disease.

Coeliac disease (CD) is becoming a model for understanding the pathogenesis of autoimmune disorders. In CD, antibodies against transglutaminase 2 (TG2) and specific residues of gliadins have been identified. A similar situation is seen in rheumatoid arthritis (RA) with both anti-citrullinated protein antibodies (ACPA) and auto-antibodies against the citrullinating enzyme, peptidylarginine deiminas

Effect of Varying Glucose Concentrations during In Vitro Maturation and Embryo Culture on Efficiency of In Vitro Embryo Production in Buffalo.

This study was aimed to optimize glucose level at different stages of buffalo in vitro embryo production procedure. Three glucose levels (1.5, 5.6 and 10 mm) along with a control (0 mm) were used at three phases of in vitro fertilisation (IVF) procedure viz. in vitro maturation (IVM), in vitro culture (IVC-I) (12-72 hpi) and IVC-II (72 hpi to 7 dpi). Maturation rate of oocytes was found different

Recent aging studies for the ATLAS transition radiation tracker

The transition radiation tracker (TRT) is one of the three subsystems of the inner detector of the ATLAS experiment. It is designed to operate for 10 yr at the LHC, with integrated charges of /spl sim/10 C/cm of wire and radiation doses of about 10 Mrad and 2/spl times/10/sup 14/ neutrons/cm/sup 2/. These doses translate into unprecedented ionization currents and integrated charges for a large-sca