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Purpose: To explore the association of frailty with mortality, functional outcome, and health status after out-of-hospital cardiac arrest.Methods: This is a cohort-based secondary analysis of the Targeted Hypothermia versus Targeted Normothermia after out-of-hospital cardiac arrest (TTM2) trial, an international, prospective, multicentre study. Frailty was assessed using the Clinical Frailty Scale

This presentation will engage with the issue of educational reform in the Middle East, discussing preliminary findings of a recently initiated research project on community based educational projects in Beirut. Such initiatives will be discussed in relation to national Lebanese educational policies and practices, as well as in relation to international educational programs such as Education for Al

Popular Abstract in Swedish Avhandlingen behandlar det nytestamentliga Judasbrevets texthistoria. Monografin inleds med en översikt av textforskningen på de Katolska Breven i allmänhet och Judasbrevet i synnerhet, från 1800-talet och fram till nutid. Mot bakgrund av det tecknade forskningsläget beskriver så författaren studiens upplägg och syfte, samt antyder några av resultaten. Det handlar främsThis study treats the textual tradition of the Epistle of Jude. After an introductory survey of earlier text-critical research, the two main purposes of this investigation are formulated: to gather and to analyze the complete textual evidence of the Epistle of Jude. The first task, to gather the evidence, involves the collation of all Greek continuous text MSS of the Epistle of Jude. The evidence

Popular Abstract in Swedish Trots att kroppen skyddas av ett hudlager på utsidan och av epitelceller i kroppens inre organ utsätts vi hela tiden för infektioner. När en vävnad blir infekterad börjar cellerna utsöndra inflammatoriska mediatorer som bland annat orsakar svullnad och rodnad. En inflammation kan också orsakas av till exempel slag eller brännskador. De inflammatoriska mediatorerna signaThis thesis describes early inflammatory responses involving interactions between leukocytes and the endothelial lining of the blood vessel wall. An adhesion molecule, E-selectin, which is upregulated on interleukin-1 activated endothelium, was found to mediate rolling between leukocytes and endothelial cells in vivo. Immunohistochemistry revealed that E-selectin was preferentially expressed in ve

Popular Abstract in Swedish En autonom agent kan definieras som ett system som med syfte att utföra uppgifter kan interagera med sin omgivning genom sina egna sensorer och effektorer. En ny arkitektur för autonoma agenter inspirerad av teorin för antecipatoriska system föreslås. Det är en hybrid arkitektur i det avseende att den kombinerar planerande förmåga, som behövs för att lösa långsiktiga prThis thesis has two main themes, autonomous agents and concepts. An autonomous agent is a system capable of interacting with its environment via its own sensors and effectors in order to accomplish some task. Arguments against both purely reactive and purely deliberative agent architectures are presented in favor for hybrid approaches. A novel hybrid approach based on the concept of anticipatory s

The CD4+ T cells have an important role in inflammation. Based on the local cytokine milieu, these cells can differentiate into either a Th1 population promoting cellular immunity or Th2 population involved in humoral immunity. Th2 cells produce the anti-inflammatory cytokines IL-4 and IL-10, which might have a protective role in autoimmune diseases like rheumatoid arthritis (RA) and multiple scle

Popular Abstract in Swedish Emilia Fogelklou (1878-1972) utbildades vid Högre Lärarinneseminariet och Uppsala universitet, där hon som första kvinna i Sverige tog en teologie kandidat (1909). En stark gudsupplevelse i unga år hade kommit att styra hela hennes liv. Hon fick så småningom sitt religiösa hem hos kväkarna. Som sökare och gränsöverskridare spände hennes liv och verk över vida fält, främEmilia Fogelklou (1878-1972) was the first woman in Sweden to take a degree in theology (1909) and later became a Quaker. She was a teacher and writer, mainly in the fields of religious education and psychology, and an active supporter of peace and other women's movements. Her autobiographical series, Arnold (1944), Bareheaded (1950), and Ready to Travel (1954), is written in the third person, Fog

Popular Abstract in Swedish ABSTRAKT Titel: Organ improvisation - activity, action and rhetorical practice [Orgelimprovisation - verksamhet, handling och retorisk praktik]. Författare: Karin Johansson Språk: Engelska Sökord: Orgelimprovisation, kulturhistorisk verksamhetsteori, högre musikutbildning, västerländsk konstmusik, diskursiv praktik, retorisk praktik. ISSN: 1404-6539 ISBN: 978-91-976053-This thesis focuses on contemporary organ improvisation in Western European musical culture. The aim of the study is to explore organists’ descriptions, constructions and definitions of improvisation in words and music, with an interest in the interaction between receptivity, creativity and change. As a research object, the art of organ improvisation is defined as a source for exploring learning a

Pharmacokinetic and pharmacodynamic activities of the antidepressants venlafaxine (VEN) and citalopram (CIT) were investigated in the portacaval shunted (PCS) rat, a model of chronic hepatic encephalopathy (HE), and normal/control rats. The levels of VEN in serum and brain were higher in PCS rats than in controls after a single injection and chronic treatment with VEN (10 mg/kg). After reducing th

Popular Abstract in Swedish När yrkesutbildningar teoretiseras ställs lärare och studerande inför skriftspråksbaserad, ofta abstrakt information som de förväntas läsa, kritiskt granska, ifrågasätta och omskapa till något eget. Språk och lärande hör nära samman, men när de studerandes vardagsspråk ska möta sådana texter kan språkandet skapa problem. Vårt sociala sammanhang har stor betydelse för vaBrandvägg describes how a group of firefighters, who consistently maintain that they are “practitioners and not theorists”, relate to various forms of language based knowledge and language based “knowledging” in their vocational training, which is based on problem based learning. From a sociocultural perspective to learning, and within the parameters of a didactic perspective with the focus on the

In many developing tropical countries, rapid urban growth leads to several problems, including increased thermal stress. This has negative consequences for people's health and well-being, and affects social and commercial outdoor activities negatively. Consequently, the creation of thermally comfortable microclimates in urban environments is highly important. The main aim of this thesis is to dee

Diamond-Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents as macrocytic anemia during infancy. Linkage analysis suggests that at least four genes are associated with DBA of which two have been identified so far. The known DBA genes encode the ribosomal proteins S19 and S24 accounting for 25% and 2% of the patients respectively. This study shows that RPS19 gene transfer

Popular Abstract in Swedish Denna avhandling redogör för cellulär lokalisation, reglering och funktion av två nya peptider, ghrelin och CART, i pankreas (bukspottskörteln). Pankreas och de Langerhanska öarna: Pankreas består av en exokrin del, som producerar matspjälkningsenzymer till mag-tarm kanalen, och en endokrin del som producerar hormoner som insöndras i blodomloppet. Endokrina pankreas bUntil recently, the islets of Langerhans were thought to harbour four main cell types characterised with respect to principal hormone product. Here we show that the novel hormone ghrelin is expressed in a fifth islet cell type, the islet ghrelin cell, in humans and rodents. The cells are developmentally regulated in that they are numerous around birth and fewer in the adult. The islet ghrelin cell

The effect of different additives on protein stability was studied, and the basis for stabilization was investigated at molecular level. The addition of sorbitol enhanced thermal stability of hen egg white lysozyme in aqueous solution. NMR spectroscopy revealed changes in the relaxation properties of Ala and Thr methyl groups in lysozyme, indicating compression of the enzyme as a consequence of pr

A phonetogram is a diagram displaying sound pressure levels (SPL) of softest and loudest possible phonation over the entire fundamental frequency range (F0) of a voice. Female singers mean phonetogram had a significantly higher upper contour than female nonsingers. When reading at various voice levels female singers produced markedly higher mean equivalent sound pressure levels (Leq) and mean rel

Cobalt oxides are known to be active catalysts for a number of chemical reactions, but very little is known about the atomic scale processesresponsible for the activity. The research presented in this thesis is focused on obtaining an atomic scale understanding of the chemistry of wellcharacterizedcobalt oxide model catalyst surfaces consisting of pristine and defective CoO and Co3O4 thin films wi

Renewable energy sources dominated the world energy supply until the beginning of the 20th century, when fossil energy became the dominant energy source worldwide. Today, fossil fuels contribute to over 80% of world energy supply. But there are two major reasons why fossil energy use has to stop. First, fossil energy is limited and will not last forever. Second, emissions of carbon dioxide change

Popular Abstract in Swedish Makrofager återfinns i stort sett överallt i kroppen. De bildas från stamceller i benmärgen och cirkulerar i blodomloppet tillsammans med andra vita blodkroppar i form av monocyter, som kan vandra igenom blodkärlens väggar och vidareutvecklas till makrofager ute i vävnaderna. Makrofagen spelar en viktig roll i kroppens totalförsvar genom att vägleda och orkestrera immunMacrophages mediate innate immunity through release of cytokines, eicosanoids, reactive oxygen species as well as through phagocytosis and secretion of lysosomal enzymes. Regulation of lysosomal secretion in macrophages differs in several respects from release of specialized granules in other leukocytes. Lysosomal secretion is not dependent upon cytosolic calcium but is instead triggered by lysoso

Popular Abstract in SwedishAvhandlingens syfte var att öka kunskapen om syskons och föräldrars erfarenheter av barn med autism och utvecklingsstörning, vad som ledde fram till beslutet att söka en plats i en gruppbostad för sitt barn och vad det innebar för föräldrar att deras barn flyttat. Avsikten var också att öka kunskapen om personalens erfarenheter av arbetet i en gruppbostad för barn med auThe aim of this dissertation was to gain knowledge about the experiences of siblings and parents of children with autism and learning difficulties, about what brought about the decision to apply for a place in a group home for their child and what it meant for the parents that their child had moved. A further aim was to gain knowledge about what it is like to work in a group home for children with

I den så kallade Snippadomen frikände Hovrätten för Västra Sverige den tilltalade från åtal om våldtäkt mot barn då målsägandens ordanvändning, bestående i ordet ”snippa”, inte ansågs ge stöd för att en penetration av målsägandens underliv ägt rum. Hovrätten hade inte diskuterat ordets betydelse med parterna under huvudförhandlingen, utan förlitade sig i slutändan på en ordboksdefinition för att uIn the so-called Snippa verdict, the Court of Appeal for Western Sweden acquitted the defendant of the charge of child rape, due to the judges’ uncertainty of the victim’s use of the word “snippa”. The Court of Appeal had not discussed the meaning of the word with the parties during the trial and ultimately relied on a dictionary definition to determine the meaning of the word, which did not suppo