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This study focuses on the interplay of molecular flexibility and hydrogen bonding manifested in the monoclinic (form I) and orthorhombic (form II) polymorphs of paracetamol. By means of incoherent inelastic neutron scattering and density functional theory calculations, the relaxation processes related to the methyl side-group reorientation were analyzed in detail. Our computational study demonstra
Allochthonous arthropods can sustain a local food web on seemingly barren land, but are nevertheless often neglected in studies of community assembly. In the present study, we investigated primary food web assembly on nunataks (ice-free areas) in a retreating glacier in Iceland. Nunataks enable studies that take into account both the temporal factor of the assembly and the influx of allochthonous
Studies of heritable colour polymorphisms allow investigators to track the genetic dynamics of natural populations. By comparing polymorphic populations over large geographic areas and across generations, issues about both morph stability and evolutionary dynamics can be addressed, increasing our understanding of the potential mechanisms maintaining genetic polymorphisms. In the present study, we
At the 7th Annual Congress of the European Association for Haemophilia and Allied Disorders (EAHAD) held in Brussels, Belgium, in February 2014, Pfizer sponsored a satellite symposium entitled: "Pharmacokinetics, phenotype and product choice in haemophilia B: How to strike a balance?" Co-chaired by Cedric Hermans (Cliniques Universitaires Saint Luc, Brussels, Belgium) and Mike Laffan (Imperial Col
Iron (Fe) is a key element, strongly influencing the biogeochemistry of soils, sediments and waters, but the knowledge about the variety of Fe species present in these systems is still limited. In this work we have used X-ray absorption spectroscopy (XAS) to study the speciation of Fe in soils and waters from a boreal catchment in northern Sweden. The aim was to better understand the controls of F
Following the line of the former Iron Curtain, the European Green Belt links protected areas across 24 countries, and restores key wildlife populations, wetlands and rural livelihoods. Its success proves that rewilding-grounded nature-based solutions can transform war-scarred frontiers into biodiversity-rich, climate-resilient lifelines, and challenges policymakers to replicate such mega-corridors
This chapter provides a normative analysis of the CJEU’s centre of gravity theory in legal basis litigation, exposing a number of flaws in its application and presenting suggestions for improvement. The chapter discusses the difficulties in the delimitation of competences under the current constitutional setup, the CJEU’s inconsistencies in applying the criteria of aim and content under the centre
Movements of individual articulators are analyzed to elucidate principles of gestural organization in vowels. Procedures for tracking articulator gestures from x-ray motion films, and results obtained on coarticulation in Swedish, Bulgarian, and Greenlandic are reported in Wood [J. Phon. 19, 281–292 (1991); Proc. 3rd Congr. I. C. P. L. A. 191–200, Helsinki (1994); Proc. 13th I. C. Ph. Sc. 1, 392–3
Neutron deficient nuclei close to Sn-100 have been investigated in-beam using the NORDBALL detector array. A target of Fe-54 was bombarded with a beam of Ni-58 at 270 MeV. Evaporation residues were identified by detecting protons and alpha particles in a 4 pi charged particle multi-detector set-up and neutrons in a 1 pi neutron detector wall in coincidence with gamma rays. Excited states of the pr
A method is described which can be used to calculate dynamic gear tooth force and bearing forces. The model includes elastic bearings. The gear mesh stiffness and the path of contact are determined using the deformations of the gears and the bearings. This gives contact outside the plane-of-action and a time-varying working pressure angle. In a numerical example it is found that the only important
OBJECTIVE--To investigate whether a lack of glutathione-S-transferase mu (GSTM1) activity was related to an increased risk for adverse outcome after asbestos exposure. METHODS--A study was made of 78 male former asbestos cement workers, with retrospective cohort data on exposure, radiographical findings, and lung function. Venous blood samples were obtained for the analysis of GSTM1 polymorphism b
Recent advances in the understanding of the epidemiology of osteoporosis suggest that certain parts of the current European guidelines for the registration of drugs in osteoporosis might be no longer substantiated. The object of this review is to provide the European regulatory authorities with an evidence-based working document providing suggestions for the revision of the "Note for guidance for
Summary. The haemophilia literature increasingly contains reports describing the use of bypassing agent prophylaxis (BAP) in patients with severe haemophilia A and inhibitors. However, it is difficult to interpret and compare the results and draw conclusions about treatment efficacy because of small patient numbers and a lack of standardization among BAP studies. This article presents consensus re
Soils collected across a long-term liming experiment (pH 4.0-8.3), in which variation in factors other than pH have been minimized, were used to investigate the direct influence of pH on the abundance and composition of the two major soil microbial taxa, fungi and bacteria. We hypothesized that bacterial communities would be more strongly influenced by pH than fungal communities. To determine the
Removal of organic micropollutants in a hybrid biofilm-activated sludge process was investigated through batch experiments, modeling, and full-scale measurements. Batch experiments with carriers and activated sludge from the same full-scale reactor were performed to assess the micropollutant removal rates of the carrier biofilm under oxic conditions and the sludge under oxic and anoxic conditions.
Deep eutectic solvents (DES) resemble ionic liquids but are formed from an ionic mixture instead of being a single ionic compound. Here we present some results that demonstrate that surfactant sodium dodecyl sulfate (SDS) remains surface-active and shows self-assembly phenomena in the most commonly studied DES, choline chloride/urea. X-ray reflectivity (XRR) and small angle neutron scattering (SAN
AimTo reconstruct spatial and temporal patterns of European fire activity during the Holocene and to explore their potential drivers, by relating biomass burning to simulated biotic and abiotic parameters. LocationEurope. MethodsHolocene fire activity was investigated based on 156 sedimentary charcoal records from lakes and peat bogs across Europe. Charcoal data covering the last 9000 years were s
The Medical ANtiarrhythmic Treatment or Radiofrequency Ablation in Paroxysmal Atrial Fibrillation (MANTRA-PAF) trial assessed the long-term efficacy of an initial strategy of radiofrequency ablation (RFA) vs. antiarrhythmic drug therapy (AAD) as first-line treatment for patients with PAF. In this substudy, we evaluated the effect of these treatment modalities on the Health-Related Quality of Life
Recently, the lineage hTURDUS2 of Haemoproteus minutus (Haemosporida, Haemoproteidae) was reported to cause mortality in captive parrots. This parasite lineage is widespread and prevalent in the blackbird Turdus merula throughout its entire distribution range. Species identity of other closely related lineages recently reported in dead parrots remains unclear, but will be important to determine fo
