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Fructose : Toxic effect on cardiorenal risk factors and redox state

AIM: To investigate the effects of fructose consumption on the antioxidant capacity in heart and kidney, cardiovascular disease risk factors, and evaluation of these variables after its removal.METHODS: Male Wistar rats (n = 36) were divided into control group (n = 12): standard chow + water or F group: standard chow + fructose in drinking water (30%) for 15 weeks. After, F group was divided to co

Adverse Pregnancy Outcomes after Multi-Professional Follow-Up of Women with Systemic Lupus Erythematosus : An Observational Study from a Single Centre in Sweden

While the management of pregnant patients with systemic lupus erythematosus (SLE) has improved over the last decades, the risk of maternal, foetal, and neonatal complications is still substantial. We evaluated the occurrence of adverse pregnancy outcomes (APO) occurring in 2002-2018 among patients with SLE from the catchment area of the Department of Rheumatology in Lund, Sweden. Longitudinal clin

Associations of global DNA methylation and homocysteine levels with abdominal aortic aneurysm : A cohort study from a population-based screening program in Sweden

Abdominal aortic aneurysm (AAA) is a life-threatening condition with a mortality rate of over 80%. Persistent smoking, which is a risk factor for AAA, has lasting effects on DNA methylation. Moreover, a plasma-amino acid, homocysteine, previously implicated in vascular diseases, including aneurysms, has well-established biological association with methylation. In the present study, we aimed to det

Disease duration, age at diagnosis and organ damage are important factors for cardiovascular disease in SLE

OBJECTIVE: To report the incidence rate ratios (IRR) of acute myocardial infarctions (AMI) and cerebrovascular events (CVE) in incident SLE cases from a defined population. To study the risk factors for cardiovascular events in all patients with SLE at our unit.METHODS: Patients with SLE diagnosed from 1981 to 2006 were followed through to 2016. IRRs of AMI and CVE were calculated. The AMI and CVE

Engineering CGTase to improve synthesis of alkyl glycosides

Alkyl glycoside surfactants with elongated carbohydrate chains are useful in different applications due to their improved biocompatibility. Cyclodextrin glucanotransferases can catalyse the elongation process through the coupling reaction. However, due to the presence of a hydrophobic tail, the interaction between an alkyl glycoside acceptor and the active site residues is weaker than the interact

Strengthening L3 French Motivation : The Differential Impact of Vision-Enhancing Activities

Even though the European Union has promoted multilingualism for long, it has proven difficult to achieve widespread multilingual language competence beyond English through formal education in Europe. In Sweden, high dropout rates have been recorded in second foreign language (SFL) classes and French is currently the most vulnerable language among the major SFLs with respect to number of pupils and

Large-eddy simulation of n-dodecane spray flame : Effects of nozzle diameters on autoignition at varying ambient temperatures

In the present study, large-eddy simulations (LES) are used to identify the underlying mechanism that governs the ignition phenomena of spray flames from different nozzle diameters when the ambient temperature (T am) varies. Two nozzle sizes of 90μm and 186μm are chosen. They correspond to the nozzle sizes used by Spray A and Spray D, respectively, in the Engine Combustion Network. LES studies of

Mechanisms of acidosis-mediated ischemic brain damage: Histopathology and pathophysiology

Exaggerated acidosis due to preischemic hyperglycemia shortens the maturation time for cell death and turns selective neuronal damage into pannecrosis. Some issues concerning the mechanisms are yet to be clarified. The present study was designed to define critical thresholds of plasma glucose, to investigate the influence of preischemic hyperglycemia on ion transients, to evaluate the role of calc

Doctoral education shapes the academy – what shapes doctoral education?

For universities all over the world, the strategic importance of doctoral education has increased over the last decades. Both locally and internationally we can observe growing activity in three interrelated areas of doctoral education: policy, knowledge formation and practice. Doctoral education is moving and has become a concern for the field of educational development. In a recent Swedish repor

Capturing everyday family practices through going-along. Methodological reflections.

In this paper I take my point of departure in a discussion around the research method of doing so called go-alongs, its possibilities and limits when trying to capture every day family practices and social differentiation. Here I am mostly interested in different aspects of work and care in relation to the practice of feeding in families with young children, a routine practice in every day family

Young people with psychiatric disabilities and their views of day centres

Young people with psychiatric disabilities may require support in structuring their everyday life. To learn more about the relevance of day centres in this respect, this study aimed to examine the experiences of young people with psychiatric disabilities. A particular focus was on the perceptions of meaningful occupation when visiting day centres, their reasons for not choosing this option when gi

Asymmetric rolling of interstitial-free steel using differential roll diameters. Part I : Mechanical properties and deformation textures

IF steel sheets were processed by conventional symmetric and asymmetric rolling (ASR) at ambient temperature. The asymmetry was introduced in a geometric way using differential roll diameters with a number of different ratios. The material strength was measured by tensile testing and the microstructure was analyzed by optical and transmission electron microscopy as well as electron backscatter dif

Asymmetric rolling of interstitial-free steel using one idle roll

The effect of additional shear on the asymmetric rolling (ASR) of an interstitial-free (IF) steel was studied by modeling and experiments. The asymmetry was introduced by making one roll idle. A 66 pct of total thickness reduction was performed in 6 passes with less than 16 pct reduction per pass. ASR was performed in two ways: monotonically and by rotating the sheet between passes by 180 deg arou

Monitoring changes in membrane polarity, membrane integrity, and intracellular ion concentrations in Streptococcus pneumoniae using fluorescent dyes

Membrane depolarization and ion fluxes are events that have been studied extensively in biological systems due to their ability to profoundly impact cellular functions, including energetics and signal transductions. While both fluorescent and electrophysiological methods, including electrode usage and patch-clamping, have been well developed for measuring these events in eukaryotic cells, methodol