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We have identified a novel protein, Leprecan-like 1 (LEPREL1), with profound similarity to the Leprecan family of proteoglycans. The genomic organization of the Leprecan gene family was found to be highly conserved. Expression analysis shows that LEPREL1 is expressed in most tissues as a 3.4 kb transcript encoding an 80 kDa protein. A LEPREL1 specific antibody stains many cell types including adip

This multicenter study describes the development of a chemoradiation protocol for the treatment of non-metastatic squamous cell carcinoma of the esophagus. Eighty patients were treated with three courses of chemotherapy (cisplatinum and 5-fluorouracil) with concomitant radiotherapy (40 Gy) during the last two courses of chemotherapy. Esophagectomy was performed, when feasible. If no operation was

Pregnancy in a rudimentary horn of a bicornuate uterus is a rare and often fatal event. A case is presented of such a pregnancy detected in the second trimester routine ultrasonographic examination.

The use of physiological data from human tests in modelling should consider background data, such as activity, environmental factors and clothing insulation on the whole body. The present paper focuses on local thermal comfort of feet with special attention on the effects of physical changes of footwear thermal properties. An alternative test method is available for footwear thermal testing beside

The thesis includes five separate studies concerned mainly with psychosocial aspects of the problems that athletes afflicted with long-term sport injuries face. The first study deals with relationships between personality variables, coping strategies and mood-levels, both in athletes participating in competitive sports and in a non-athlete reference groups. The results indicate the athletes to us

Patients with a previous history of anaphylactic reactions to ionic iodinated contrast media were desensitised before a second radiologic examination was performed. The tolerance to the contrast medium was raised by repeated intravenous injections in increasing doses and concentrations. No serious side effects were noted when the examinations with contrast medium was repeated within a few days aft

In order to investigate and describe the drying kinetics occurring in a porous material during superheated steam drying, a model was developed based on the fundamental transport equations for mass and heat. The driving forces in the model are gradients of moisture, temperature and pressure. The transport coefficients employed were either measured experimentally or were derived theoretically from t

A systematic review of radiation therapy trials in several turnout types was performed by The Swedish Council of Technology Assessment in Health Care (SBU). The procedures for evaluation of the scientific literature are described separately (Acta Oncol 2003; 42: 357-365). This synthesis of the literature on radiation therapy for head and neck cancer is based on data from 39 randomized trials and I

Objective: To discover a possible absorption and/or secretion of enterostatin into the circulating blood, as well as to compare the levels of circulating enterostatin after high-fat feeding and low-fat feeding. Research Methods and Procedures: Using a specific enzyme-linked immunosorbent assay, plasma enterostatin levels were determined after feeding a high-fat, a high-fat/sucrose, or a low-fat me

Discussion and debate regarding decision-making that is 'in the best interest of the child' and that also considers the child's voice in these decisions have increased in recent years. A study was undertaken to identify everyday situations in medical and nursing care in which children had been allowed to have a voice or been denied the right. Twenty-six hospitalized children, ages 6 to 17 years, a

Popular Abstract in Swedish Papperstillverkning inkluderar flera processteg såsom flisning av träråvaran, massakokning och avvattning med vakuumlådor, pressning och torkning. Flera modeller av de mest viktiga processerna i torkpartiet presenteras i denna avhandling. Modellerna beskriver både statiska och dynamiska förlopp. Nya reglerstrategier som kan användas för både reglering vid stationär drifThe paper making process involves chopping of wood, cooking and forming, followed by dewatering in a vacuum section, press section and drying section. Several models for the most important parts of the paper machine drying section are presented in this thesis to describe phenomena at steady state and during state transitions. New control strategies applicable/useful for both steady-state control a

Popular Abstract in Swedish Parkinsons sjukdom beror på att de dopamin-producerande cellerna i hjärnan dör. Detta leder till minskad rörlighet, svårigheter i att påbörja och avsluta en rörelse, balanssvårigheter och darrningar (tremor) hos de drabbade patienterna. Varför dopamincellerna dör är oklart och i nulägat kan man inte bota Parkinsons sjukdom, men man kan lindra symptomen med mediciner. PaParkinson's disease (PD) is a neurodegenerative disorder where the midbrain dopaminergic neurons are lost. Presently there is no cure for PD, and the most common treatment is to replace the lost dopamine pharmacologically by administration of the dopamine precursor L-DOPA. This works very well during the initial treatment period, but unfortunately a majority of the patients develop abnormal involu

Violaxanthin deepoxidase (VDE) has been purified from spinach (Spinacia oleracea) leaves. The purification included differential sonication of thylakoid membranes, differential (NH4)2SO4 fractionation, gel filtration chromatography and finally either hydrophobic interaction chromatography or anion exchange chromatography. A total purification of more than 5000-fold compared to the original thylako

Observer performance studies are time-consurning tasks, both for the participating observers and for the scientists collecting and analysing the data. A possible way to optimise such studies is to perform them in a completely digital environment. A software tool-ViewDEX (Viewer for Digital Evaluation of X-ray images)-has been developed in Java, enabling it to function on almost any computer. ViewD

Background: Loss of chromosome 11q defines a subset of high-stage aggressive neuroblastomas. Deletions are typically large and mapping efforts have thus far not lead to a well defined consensus region, which hampers the identification of positional candidate tumour suppressor genes. In a previous study, functional evidence for a neuroblastoma suppressor gene on chromosome 11 was obtained through m