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The deletion (5q) karyotype (del [5q]) in patients with myelodysplastic syndrome (MDS) is the most common karyotypic abnormality in de novo MDS. An increased number of blasts and additional karyotypic abnormalities (del [5q]+) are associated with a poor outcome. We analyzed the outcome of allogeneic hematopoietic cell transplants (HCT) in patients suffering from MDS with only del (5q) or del (5q)+
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Background: Emergency medical dispatching should be as accurate as possible in order to ensure patient safety and optimize the use of ambulance resources. This study aimed to compare the accuracy, measured as priority level, between two Swedish dispatch protocols - the three-graded priority protocol Medical Index and a newly developed prototype, the four-graded priority protocol, RETTS-A. Methods:
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When a human catches a ball, they estimate future target location based on the current trajectory. How animals, small and large, encode such predictive processes at the single neuron level is unknown. Here we describe small target-selective neurons in predatory dragonflies that exhibit localized enhanced sensitivity for targets displaced to new locations just ahead of the prior path, with suppress
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This study explores how a platform approach facilitates the implementation of advanced service offerings in manufacturing firms. Understanding servitization through a platform approach is important because many manufacturing firms fail to manage the service paradox, that is, the challenge of simultaneously enriching the value proposition by adding services while maintaining cost levels. This study
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The main challenge in predicting structure-borne sound in wood buildings is to accurately model the vibration transmission between the source and the receiving room. Large variations in model parameters make it difficult to predict absolute vibration levels and to make conclusions regarding the relative effects of different designs. A step towards establishing reliable models is to investigate the
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We study the temporal evolution of a small number N of ultra-cold bosonic atoms confined in a ring potential. Assuming that initially the system is in a solitary-wave solution of the corresponding mean-field problem, we identify significant differences in the time evolution of the density distribution of the atoms when it instead is evaluated with the many-body Schrödinger equation. Three characte
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Most cases of hemolytic uremic syndrome (HUS) are caused by infection with enterohemorrhagic Escherichia coli (EHEC). Genetic defects causing uncontrolled complement activation are associated with the more severe atypical HUS (aHUS). Non-EHEC infections can trigger the disease, however, complement defects predisposing to such infections have not yet been studied. We describe a 2-month-old patient
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Measurement of endwall heat transfer around a circular cylinder with a vortex generator pair has been investigated. Steady state liquid crystal thermography is adopted. Cylinders having two different height to diameter ratios have been employed. In one case, the cylinder has one end free in the flow and in the other case it has both ends attached on the walls. Local Nusselt numbers both upstream a
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Background Strength training has shown effects in reducing neck pain. As neck pain is highly prevalent in tension-type headache (TTH), it is relevant to examine the effect of strength training of the shoulder muscles on TTH patients. Aim To examine the effect of strength training of the shoulder/neck muscles on TTH frequency and duration. Methods Sixty patients with TTH were randomised into streng
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The formation of new atmospheric particles involves an initial step forming stable clusters less than a nanometre in size (<~1 nm), followed by growth into quasi-stable aerosol particles a few nanometres (~1-10 nm) and larger (>~10 nm). Although at times, the same species can be responsible for both processes, it is thought that more generally each step comprises differing chemical contributors. H
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This paper presents achievable uplink (UL) sum-rate predictions for a measured line-of-sight (LOS) massive multiple-input, multiple-output (MIMO) (MMIMO) scenario and illustrates the trade-off between spatial multiplexing performance and channel de-coherence rate for an increasing number of base station (BS) antennas. In addition, an orthogonal frequency division multiplexing (OFDM) case study is
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Digitalization is fundamentally changing the retailing ecosystem for shopping malls as digital and analogue elements get increasingly intertwined. We conceptualize shopping malls as two-sided markets whose primary function is connecting shoppers and retailers. By means of an interpretative case study, the article then presents an omnichannel strategy typology for how shopping malls can meet the ev
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This paper investigates the interaction between economic, demographic and educational variables in post-World War II France. Based on the assumptions of the unified growth theory, we estimate a vector auto-regression for data on fertility, GDP per capita, educational attainment, labor force participation and wages over the period 1962-2008. The methodology employed is based on VAR modeling, using
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The study of evolution in a palaeontological context is chiefly the study of change in shape and form. This requires data sets that quantify morphology and morphological variation. Historically morphology has been described using discrete characters or more recently using various morphometric approaches. Elliptical Fourier analysis (EFA) is an approach to quantifying morphology that results in the
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Willingness-to-pay (WTP) techniques are increasingly being used in the healthcare sector for assessing the value of interventions. The objective of this study was to estimate WTP and its predictors in a randomized controlled trial of a lifestyle intervention exclusively targeting Middle Eastern immigrants living in Malmö, Sweden, who are at high risk of type 2 diabetes. We used the contingent va
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Monte Carlo simulations have been performed for two simple models of a titrating polyelectrolyte: (i) a rigid rod and (ii) a freely jointed chain. Both models have fixed bond lengths, and the polyelectrolyte charges interact through a screened Coulomb potential. Chains consisting of 80-1000 monomeric units have been studied at three salt concentrations: 0.001, 0.01, and 0.1 M. Conformational prope
