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The cognitive abilities explained by cognitive science and cognitive semantics can inform us concerning the use of metaphors in science. The thesis is that abstract ideas rest on experiences of the concrete world. In this paper I will explain the use of conceptual metaphors in science, with examples from the mechanistic worldview of the 17th and 18th century. If we proceed from the way people thin
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The European Union directive on Intellectual Property Rights Enforcement (IPRED) was implemented in Sweden on April 1, 2009, and was meant to be the enforcement needed to achieve increased compliance with intellectual property online, especially copyright. This, therefore, was the manifest function of the directive. The article empirically shows changes in levels of use of Online Anonymity Service
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Popular Abstract in Swedish En av de stora vetenskapliga bedrifterna hittills under 2000-talet är onekligen att man efter många års arbete för första gången lyckades kartlägga (sekvensera) samtliga mänskliga gener. Det mänskliga DNA:t är lokaliserat till cellkärnan och i princip så kan man likna en cellkärna med ett kontrollrum fyllt av manualer (DNA) som talar om cellens sammansättning och hur deProteomics is expected to generate new insights into biological processes as well as identify novel biomarkers and therapeutic targets since most biological functions are transmitted through proteins. However, due to the complexity displayed by a proteome and inherent limitations associated with current methodologies, proteomic analyses often result in incomplete coverage and inconsistent measurem
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The growing field of biotechnology is in constant need of proteins that can function as recognition tools for separational, analytical and therapeutic purposes. Different molecular engineering approaches are applied on natural proteins in order to create variants with desired properties. This thesis is based on five original papers that deal with selection, characterisation and application of nove
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1. Introduction; 2. Indexical self-awareness; 3. Detached self-awareness; 4. Social self-awareness; 5. Basic social self-awareness; 6. Developed social self-awareness; 7. Person-consciousness
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The aim of the study was to review studies concerning single-set and multiple-set resistance training. Twenty-six articles were found, 19 randomized controlled trials and seven studies without randomization process. Out of the 26 articles, 11 showed similar increases in strength when comparing number of sets, mostly one set compared with three sets. Eight of the articles showed a greater increase
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Excessive sweating is a major ergonomic concern in bicycle helmet use and low wearing rates are suspected to originate, at least partly, from impaired thermal comfort due to accumulated sweat increasing skin wettedness at the head region. As a development from COST Action TU1101 WG4, we introduce a modelling framework for assessing the thermal comfort of bicy-cle helmet use. We predicted local swe
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Background: Knowledge of the radiographic catheter tip position after central venous cannulation is normally not required for short-term catheter use. Detection of a possible iatrogenic pneumothorax may nevertheless justify routine post-procedure chest X-ray. Our aim was to design a clinical decision rule to select patients for radiographic evaluation after central venous cannulation. Methods: A t
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BACKGROUND AND PURPOSE: This study aims to investigate the process of monitor unit verification using control charts. Control charts is a key tool within statistical process control (SPC), through which process characteristics can be visualized, usually chronologically with statistically determined limits. MATERIAL AND METHODS: Our group has developed a monitor unit verification software that has
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A system arising in the modeling of oil-recovery processes is analyzed. It consists of a hyperbolic conservation law governing the saturation and an elliptic equation for the pressure. By an operator splitting approach, an approximate solution is constructed. For this approximation appropriate a-priori bounds are derived. Applying the Arzela-Ascoli theorem, local existence and uniqueness of a clas
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Intestinal ischemia as well as mastocytosis occur in patients with inflammatory bowel disease and irritable bowel syndrome. Our aim was to clarify how ischemia with reperfusion (I/R) affects the structure, enteric neurons, and immune cells in the colon. Rats were subjected to colon ischemia for 1 h and reperfused for 1 day up to 20 weeks; sham-operated rats were used as controls. No structural rem
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Progressive multifocal leucoencephalopathy (PML) is a viral infection occurring in immunocompromised patients. The typical magnetic resonance imaging (MRI) findings include supratentorial asymmetric nonenhancing white matter lesions without mass effect. We present a patient with progressive cerebellar and brain stem lesions, emphasizing the fact that the diagnosis of PML should be considered also
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The transcription factor T-cell factor 7-like 2 (TCF7L2) confers type 2 diabetes risk mainly through impaired insulin secretion, perturbed incretin effect and reduced beta-cell survival. The aim of this study was to identify the molecular mechanism through which TCF7L2 influences beta-cell survival. TCF7L2 target genes in INS-1 cells were identified using Chromatin Immunoprecipitation. Validation
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Working as hairdressers has been associated with increased risk for cancer, particularly bladder cancer. To evaluate if current hairdressers have elevated risks of adverse health effects, we measured several biomarkers related to cancer-related DNA alterations. We enrolled 295 hairdressers and 92 non-hairdressers (all female non-smokers) from Stockholm and southern Sweden. Questionnaire data were
