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Altered DNA methylation is often seen in malignant cells, potentially contributing to carcinogenesis by suppressing gene expression. We hypothesized that heritable methylation potential might be a risk factor for breast cancer and evaluated possible association with breast cancer for single nucleotide polymorphisms (SNPs) either involving CpG sequences in extended 5'- regulatory regions of candida
Disperse dyes are well-known contact sensitizers. However, they are not included in the majority of commercially available baseline patch test series.
Building on Forney's concept of the genie (1972), and introducing the idea of an explicit statistical description of the side information provided to the genie-aided detector, we develop a generic tool for derivation of lower bounds on the bit-error rate of any actual receiver. With this approach, the side information statistics become design parameters, which may be chosen to give the resulting b
This paper presents a simulation model that has been developed to analyse how the application of Radio Frequency Identification technology (RFID) affects material handling activities in a retail distribution centre. The simulation model handles both stochastic and dynamic behaviours, and describes how the receiving, picking and shipping activities will behave and perform over time when RFID tags a
An inverse source problem associated with a semi-linear transport or one-way wave equation in one spatial dimension is considered. It is shown an analytic solution to the inverse problem can be given and furthermore, that this inverse problem of determination of a source function is ill-posed, and must be regularised. A novel regularisation scheme which combines least squares monotone approximatio
In this paper I consider whether eudamonism—i.e. the thesis that the ultimate aim of human life and conduct is the attainment of happiness and that the achievement of this goal is closely linked to the acquisition and exercise of moral virtue and tranquillity of the soul—could serve as a framework for a theory of rights. I argue that the eudaimonist’s chances to ground a theory of rights from with
Abstract is not available
Prevailing approaches of planning and strategy making, which traditionally deal with the states of systems in terms of fixed goals, fail to acknowledge the process nature of sustainable development. Using a system dynamics approach and relying on the concept of viability loops, the paper aims to illustrate a practical implementation of sustainable development with an urban water system as an examp
This is the first attempt to budget average current annual carbon (C) and associated greenhouse gas (GHG) exchanges and transfers in a subarctic landscape, the Lake Torneträsk catchment in northern Sweden. This is a heterogeneous area consisting of almost 4000 km2 of mixed heath, birch and pine forest, and mires, lakes and alpine ecosystems. The magnitudes of atmospheric exchange of carbon in the
Background: It is well established that Libya is lagging behind its peers in biomedical research. The aim of this study is to analyse all the original biomedical publications affiliated with Libya from 1973 to 2007. Methods: PubMed and the Science Citation Index Expanded were searched for 'original research' biomedical studies affiliated with Libya. The generated data were hand searched and 329 'o
In this paper a method for the analysis of a frequency selective surface (FSS) supported by a bianisotropic substrate is presented. The frequency selective structure is a thin metallic pattern — the actual FSS — on a plane supporting substrate. Integral representations of the fields in combination with the method of moments carried out in the spatial Fourier domain are shown to be a fruitful way of
Caregiving relatives continue to feel primarily responsible for the care and well-being of elderly persons, when they are admitted to hospital. Although involvement of relatives in decision-making is rare, and the hospitalisation therefore may be a frustrating experience, little is known of relatives, experience of the hospitalisation of elderly persons from a life-world perspective. In this pheno
BACKGROUND: The Palliative Medicine Unit at University Hospital of Trondheim, Norway, started an intervention programme that aims to enable patients to spend more time at home and die there if they prefer. Close cooperation was needed with the community health-care professionals, who acted as the principal formal caregivers, and a multidisciplinary consultant team coordinated the care. We did a cl
The transport of PCBs (Aroclor 1242) in a river system in southern Sweden was governed by outflow from sediment in a 26-ha contaminated lake. Experiments in the lake revealed that 14 g PCBs/d escaped from the sediment, while sedimentation was 3 g PCB/d. Volatilization of PCBs from the lake surface was 0.02 g/d, which was considerably higher than the atmospheric fallout . The majority of the sedime
Vitrectomy requires the substitution of the natural vitreous, as well as tamponading of retinal breaks. Clinically available alternatives such as gas and silicone oil have side effects such as inflammation, secondary glaucoma, cataract, and a need for head posturing. In this study, a hydrogel of cross-linked sodium hyaluronic acid (Healaflow(®)) is evaluated for use as a novel vitreous substitute.
Since the publication of O'Regan and Noë's original article in Behavioral and Brain Sciences in 2001, which first set out the sensorimotor account by which sensory experience and motor engagement are inextricably intertwined, there have been not just one but many sensorimotor accounts. However, in many ways that original article remains the canonical account. In this paper, I discuss a particular
