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In this review we discuss the influence of chaperones on the general phenomena of folding as well as on the specific folding of an individual protein, MHC class I. MHC class I maturation is a highly sophisticated process in which the folding machinery of the endoplasmic reticulum (ER) is heavily involved. Understanding the MHC class I maturation per se is important since peptides loaded onto MHC c
Enzymatic hydrolysis is an agro-processing aid that can be utilized in order to improve nutritional quality of protein extracts from many sources. In this study, protein extracts from ungerminated and/or germinated local Egyptian soybean and lupin flours were hydrolyzed using the enzyme papain. The hydrolysis processes were carried out for 2 h and aliquots were withdrawn at different time interval
There is a need for mathematical modelling for the evaluation of important parameters for photon imaging systems. A Monte Carlo program which simulates medical imaging nuclear detectors has been developed. Different materials can be chosen for the detector, a cover and a phantom. Cylindrical, spherical, rectangular and more complex phantom and source shapes can be simulated. Photoelectric, incoher
An increasing incidence of testicular cancer has been reported from several western countries during the last decades. According to current hypothesis testicular cancer is initiated during the foetal period and exposure to endocrine disruptors such as some persistent organic pollutants has been of concern. We have previously reported the results for concentrations of polychlorinated biphenyls (PCB
Systemic lupus erythematosus (SLE, OMIM 152700) is a complex autoimmune disease that affects 0.05% of the Western population, predominantly women(1-4). A number of susceptibility loci for SLE have been suggested in different populations, but the nature of the susceptibility genes and mutations is yet to be identified(5-9). We previously reported a susceptibility locus (SLEB2) for Nordic multi-case
The irritation response of the rabbit eye to trigeminal nerve stimulation, which includes a breakdown of the blood-aqueous barrier (BAB), seems to be due to the release of substance P (SP) and calcitonin gene-related peptide (CGRP). In order to assess the relative importance of these two peptides for the barrier effect, and the role of arachidonic acid metabolites (AAM) in the response, we have st
Objective To assess the prevalence of hypertension and use of antihypertensive drug therapy in relation to menopausal status and to delineate perceived associations between androgens and blood pressure in perimenopausal women. Methods A population- based sample of women aged 50 - 59 ( nU6893). Women were divided into three groups according to their hormonal status: premenopausal, postmenopausal wi
This paper describes one possible method for using subject pools other than undergraduate students. We also report the results from an experiment in which 145 subjects belonging to a specific church in Dar-es-Salaam, Tanzania were exposed to a Trust Game and a standard set of attitudinal survey questions in order to study trust and trustworthiness, two concepts that are likely to be at the core of
Artikeln ”Facklig styrka eller reformistisk strategi?” publicerades i Zenit nr 4 (nr 86) 1984 som en kommentar till Anders Perssons recension i Zenit nr 2 (nr 84) 1984 av Anders Kjellbergs doktorsavhandling Facklig organisering i tolv länder (Lund: Arkiv förlag 1983). Redaktionen klippte dock av utrymmesskäl bort ett stycke som under rubriken ”Facklig styrka – än en gång!” publicerades i Zenit nr
The workshop Reglermöte 85 was arranged during May 29-30 1985 at the Department of Automatic Control at Lund Institute of Technology. About 100 persons participated evenly divided between industry and universities. 18 papers were presented. Abstracts of the papers are given in the report.
Den praktiska tillämpningen av de utförda beräkningarna kan sammanfattas i följande punkter: - Den gynnsamma effekten på uttorkning av byggfukt, som erhålles av mineralullsisolering och slopande av ångspärr, kan lnte utnyttjas vid golvvärme annat än möjligen i undantagsfall. Fukttillförseln underifrån riskeras bli a1ltför stor om golvvärmen stängs av mer än 3 - 4 månader för ett ordinärt småhus. -
This dissertation contains a variety of contributions to econometric theory. Broadly speaking, econometrics may be categorized depending on what type of data is being analyzed, the two main categories being time series data and cross sectional data. A third category is panel data, combining cross sectional data observed over time. This is the area at which this dissertation is aimed. Panel data mo
In nuclear reactors plutonium and transplutonium isotopes are produced by multiple neutron capture of uranium and plutonium and are important for the energy production and their composition reflects the core burnout. Under normal operation these elements are not released to the environment in significant amounts. There are accordingly very few areas or source terms where exotic transplutonium elem
Background. An abnormally high [above mean + 2 standard deviations (SD)] umbilical artery (UA) pulsatility index (PI) indicates impaired fetal outcome, whereas the impact of an "abnormally" low (below mean -2 SD) PI is unknown. Methods. Perinatal outcome was compared between cases with a UA PI less than mean -2 SD (group A: high-risk cases selected from a database, n = 330; group B: unselected ca
The high-molecular-mass salivary mucin MG1, one of two major mucins produced by human salivary glands, plays an important role in oral health by coating the tooth surface and by acting as a bacterial receptor. Here this mucin was purified from the submandibular/sublingual saliva of a blood group O individual. The presence of MUC5B as the major mucin in this preparation was confirmed by amino acid
Swanströms doktorsavhandling undersöker fyra aspekter på den separatistiska rörelsen i Österbotten utifrån Catharina Asplund, Abraham Achrenius, Johan Bullich och Friedrich Basilier. Avsnitten präglas av personernas anknytning till maktperspektiv, apokalyptik och själavård, uppror och mental ohälsa, resp. ekonomiska svårigheter. Förf. har bearbetat obeaktat material och kombinerat det med välbekan
110 patients with non-operated on fracture of the lateral end of the clavicle were reviewed on an average 15 years after the injury. There were 73 undislocated Neer Type I fractures, 23 dislocated Type II fractures and 14 intraarticular Type III fractures. The patients' age at trauma was 36 (2-71) years. At follow-up 95 shoulders were asymptomatic. 15 shoulders had moderate pain and dysfunction an
