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2022 has not been a good year for Facebook (Meta) so far. The stock price is plunging, the company is still under fire for the extent of misinformation on the platform, and the number of users are decreasing for the first time in the US. Marketing and technology analysts are speculating whether Facebook reached its peak and began losing the competition against other rising platforms like TikTok.Ye

Abstract in ItalianUn’accesa e radicale tensione nelle scienze cognitive è quella tra il cognitivismo e il cosiddetto approccio delle quattro E (Embodied, Enactive, Embedded e Extended). La mancanza di una riflessione aperta e sostanziale sul lavoro teorico ed empirico proposto dall’approccio opposto appare problematica da entrambe le parti. Il presente contributo analizza a fondo le evidenze empiIn philosophy and cognitive science, the tension between cognitivism and the 4E-Cognition approach is both deep and polarizing. A lack of serious engagement with the theoretical and empirical work generated by the opposing framework seems problematic on both sides. In this paper, we closely discuss data on early socio-cognitive development produced by an influential nativist current of thought in

Pretend play has been studied in great depth in the past four decades, yielding an increasingly rich body of evidence and conjectures about the evolutionary, cognitive, social and linguistic competence acquired by young children through make-believe activities. In the current work, we drew connections between symbolic play and early forms of infants’ humorous initiatives, such as clowning and teas

This study aims at exploring disability, health-related quality of life (HrQoL), psycholog- ical distress, and psychological features in post-stroke patients with chronic pain. An observational cross-sectional study involving 50 post-stroke patients (25 with chronic pain and 25 without pain) was conducted. The primary outcome was the self-reported level of disability and HrQoL which were both asse

The Swedish national guidelines for treatment of acute myeloid leukemia (AML) recommend analysis of measurable residual disease (MRD) by multiparameter flow cytometry (MFC) in bone marrow in the routine clinical setting. The Swedish AML registry contains such MRD data in AML patients diagnosed 2011-2019. Of 327 patients with AML (non-APL) with MRD-results reported in complete remission after two c

AML with mutated NPM1 occurs in all age groups. Yet, the mutational pattern is not extensively studied in the very old, which may hamper appropriate risk assessment. Herein we examined 22 cases of NPM1-mutated de novo AML in patients older than 75, with a median age of 84. All diagnostic samples were sequenced aiming for coverage of the most relevant AML-associated mutations. For comparison with y

New therapeutic agents for haemophilia with inhibitors that are in development or already licensed are expected to provide transformative treatment options. Many of these new therapies are not based on simply replacing the missing factor; new strategies include bispecific antibody technology that mimics factor VIII coagulation function (emicizumab), and inhibition of anticoagulant proteins such as

In Latin-America -as in most parts of the world- indigenous peoples are ‘the poorest of the poor, and the most excluded of the excluded’. Poverty goes hand in hand with their situation of vulnerability, exclusion and disempowerment. How can this situation be changed? How to find adequate frameworks able to facilitate the overturn of their structural disenfranchisement? Departing from the jurisprud