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Using several melanoma proteomics data sets we created a single analysis platform that enables the discovery, knowledge build, and validation of diagnostic, predictive, and prognostic biomarkers at the protein level. Quantitative mass-spectrometry-based proteomic data was obtained from five independent cohorts, including 489 tissue samples from 394 patients with accompanying clinical metadata. We

Industries across the globe are making arduous efforts to mitigate emissions and use greener ways of transporting goods and delivering services. The supply chain includes all the activities which involve producing, transporting, and distributing goods and services, contributing to a major portion of worldwide emissions. Road transport contributes majorly to emissions; therefore, focusing on net-ze

Fuel cell electric vehicles (FCEVs) are gaining global attention as a sustainable transportation solution, yet their adoption in emerging South Asian economies remains limited. This study addresses the research gap by identifying and prioritizing barriers to FCEV adoption in India, Pakistan, and Bangladesh, regions underrepresented in existing literature. A hybrid methodology integrating Explorato

Urban expansion has led to ever increasing noise and light pollution, which impairs the audio-visual perception of wild animals and drives changes in key activities and behaviours. Nocturnal predators may be especially affected in detecting prey, with potentially dramatic consequences for their fitness. However, the combined effects of noise and light pollution on predator performance are still mo

Hemispheric asymmetry is a universal property of brain organization with wide implications into brain function and structure, and diseases. This study presents a laterality index for characterizing hemispheric asymmetries that underlie cortical maps using geometric eigenmodes derived from human cortical surfaces. We develop a generalized design to quantify asymmetries across various cortical spati

The present study investigates the integration of Lean and Sustainable manufacturing (LSM) practices to improve the market competitiveness of Indian manufacturing organizations. The study aims to explore the critical role of stakeholder commitment to drive both sustainable manufacturing and lean practices with their impact on manufacturing competitiveness. In the study a survey-based approach was

Aims: The objective of this study was to compare the risk of developing type 1 diabetes in individuals with celiac disease, hyperthyroidism and hypothyroidism to that of individuals without those conditions. Materials and Methods: In this retrospective, observational, matched-cohort study based on real-world claims data, individuals with at least one diagnosis of celiac disease, hyperthyroidism (e

Vital to the economy, culture and landscape of many regions around the world, the olive sector faces significant challenges, including rising production costs, labour shortages, climate change impacts, water scarcity, quality control issues and market demands for transparency and authenticity. Digital and other Industry 4.0 technologies offer transformative potential to address these pressures. Th

Currant, and in particular blackcurrant, Ribes nigrum, is widely grown in Europe. It is the host of a number of pest insects, but their occurrence and the damage they cause vary geographically. In northern Europe, three lepidopteran species, the currant shoot borer (Lampronia capitella), the currant clearwing (Synanthedon tipuliformis), and the currant bud moth (Euhyponomeutoides albithoracellus),

Ordet vingelmån vid ledningsrätt och koncession är ett i stort sett outforskat begrepp. Syftet med detta examensarbete är att utreda hur mycket förändringar som kan göras i ledningarnas placering, hur mycket stolpar kan förflyttas och vilken vingelmån som finns i ledningsrätt och koncessioner för starkströmsledningar. För att undersöka frågan gjordes en litteraturstudie med hjälp av böcker, rättsThe purpose of this essay is to explore power lines from a legal point of view and investigate the limits of what is possible to build within the concession order as well as the utility easement. This essay explores minor deviations from concession and utility easement when constructing or reconstructing a powerline. A literature study has been conducted alongside semi-structured interviews. To ge

The major challenges faced by confectionery supply chain are lack of information, traceability, managing the ownership of goods across supply chains, inability to track vendors in real-time. Blockchain and Internet of Things (IoT) in Industry 4.0 era help organisations to overcome these challenges by guaranteeing authentic information, real-time visibility, and transparency across the supply chain

The Swedish population is characterized by high life expectancy and low avoidable mortality rates. This review outlines the Swedish healthcare system, which offers universal access to all residents and has a long tradition of reforms for social equity. Responsibility for healthcare is shared between the state, the regions, and the municipalities. The Ministry of Health and Social Affairs provides

Syftet med den aktuella studien var att undersöka behandlares erfarenheter av att leda compassionfokuserad terapi (CFT) i gruppformat i svensk kontext. Studien syftade till att belysa vilka möjligheter och utmaningar behandlarna upplevde i arbetet och hur de beskrev sin roll som gruppledare. Sex terapeuter som har genomfört minst en 12-veckors behandling i CFT intervjuades. Datainsamlingen skedde The aim of this study was to explore therapists’ experiences on facilitating compassion-focused therapy (CFT) in a group format within a Swedish context. The present study sought to examine the opportunities and challenges the therapists experienced in their work, as well as how they described their role as group leaders. Six therapists who had conducted at least one 12-week CFT group treatment we

This study investigates isoprene emissions in a high-latitude Alpine tundra ecosystem, focusing on using near-field remote sensing of surface temperatures, the photochemical reflectance index (PRI) and normalized difference vegetation index (NDVI), and meteorological measurements to model these emissions. Isoprene is a key biogenic volatile organic compound (BVOC) emitted by select plants, which c

Purpose: To map and summarise the available knowledge regarding older adults’ experiences of team-based home rehabilitation. Method: The Johanna Briggs Institute (JBI) guidelines for scoping reviews guided the process. Eight databases, eight organisational websites, one registry and Google Scholar were searched. Searches were limited to publications published from 2006 to 2023 in English and Scand

Introduction: Acute lower limb ischemia (ALI) is a life and limb threatening event often affecting patients with type 2 diabetes mellitus (T2DM). Little is known about how T2DM affects the risk of adverse events in patients revascularized for ALI. This study aimed to investigate if there were differences in major outcomes between ALI patients with and without T2DM. Methods: Between 2010 and 2014,

Purpose: Consistent, accurate postoperative guidance is crucial for early recovery and patient satisfaction in urology, especially for radical prostatectomy (RP) patients. However, patients often receive inconsistent information, highlighting the need for standardized, evidence-based postoperative care guidelines. Materials and Methods: We conducted a comprehensive review and evaluation of current