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Due to the lower radiative fraction and typically higher storage pressures, gas temperatures can often result in longer safety distances compared to radiative heat transfer for hydrogen jet flames. The high temperatures, however, also lead to a low density causing the flow to rise at a certain distance from the release. Unfortunately, a model to determine this distance, similar to what is availabl
Fire retardants are extensively used to reduce the flammability (combustibility) of wood–based construction materials in an effort to improve fire safety of buildings. However, little is known of the composition and potential risks to human health of smoke emissions produced from combustion of fire retardant treated wood. To help understand the risk to human health, fire smoke emissions produced f
This study investigates “stiffness” optimization of path-dependent elasto-plastic structures by comparing the traditional secant stiffness formulation with a novel tangent stiffness formulation. Design updates are generated using the gradient-based Method of Moving Asymptotes (MMA), and the material behavior is modeled and limited to small-strain elasto-plasticity and isotropic hardening. Numerica
Vision impairment increases risks such as social isolation, mobility challenges, and falls. Wearable Augmented Reality (AR) devices with Artificial Intelligence (AI) can enhance sensory perception by enabling real-time recognition of obstacles, assisting visually impaired individuals during street navigation, aiming to reduce the risk of falls. In this paper, we propose a Federated Learning (FL) f
The fire behaviour of bio-based insulation materials is studied by comparing results from Cone Calorimeter and small-scale furnace tests. Clear differences in fire behaviour were observed between wood fibre and hemp fibre insulation. The analysis reveals that smouldering plays a critical role, particularly in furnace tests. Limitations of current fire resistance tests are highlighted, particularly
Bio-based insulation materials, such as wood fiber, offer sustainable alternatives to conventional insulation but pose challenges due to their combustibility, particularly their smouldering behavior. This study investigates the heat release characteristics of wood fiber insulation using a combination of Simultaneous Thermal Analysis (STA) and Microscale Combustion Calorimetry (MCC) to assess both
Background: Various plasma phosphorylated tau species have been shown to be associated with amyloid-β (Aβ) PET and Tau PET in Alzheimer’s disease (AD), but whether APOE ε4 affects the interaction between glial fibrillary acidic protein (GFAP) and phosphorylated tau (pTau), and whether a three-way interaction exists among APOE ε4, GFAP, and pTau that influences AD progression remain unclear. Method
Despite significant progress in oncology research, pancreatic cancer remains inherently difficult to treat, and the mechanisms underlying therapeutic resistance remain unresolved. Decorin (DCN), a member of the family of small leucine-rich proteoglycans, has emerged as a versatile actor in various malignant diseases. The aim of this study was to further explore the potential clinical significance
This paper addresses the path-tracking problem of time-optimal trajectories under model uncertainties, by proposing a real-time predictive scaling algorithm. The algorithm is formulated as a convex optimization problem, designed to balance the trade-off between improving feasibility and time optimality of a trajectory. The predicted trajectory is scaled based on the presence of path segments that
Dexterous in-hand manipulation offers significant potential to enhance robotic manipulator capabilities. This paper presents a sensori-motor architecture for in-hand slip-aware control, being embodied in a sensorized gripper. The gripper in our architecture features rapid closed-loop, low-level force control and is equipped with sensors capable of independently measuring contact forces and sliding
Arbetets syfte är att genom intervjuer ta reda på hur viktigt samverkan och företagsamhet är för alla musiker och kompositörer. Hur hör detta ihop med lyssnande och samverkan i repetitions- eller konsertsalen? Vad tycker dirigenten är viktigt för att driva en orkesterrepetition framåt? Vilken väg ska en kompositör gå för att komma i kontakt med konserthusen? Med intervjuer av kollegor och professoThe aim of the work is to find out through interviews how important collaboration and entrepreneurship are for all musicians and composers. How does this relate to listening and collaboration in the rehearsal or concert hall? What does the conductor think is important to drive an orchestral rehearsal forward? What route should a composer take to get in touch with concert halls? Through interviews
Background: The biodistribution of PSMA-ligands is of interest in radionuclide therapy planning. We investigated the variability of [18F]PSMA-1007 uptake in organs at risk and in relation to tumour burden in prostate cancer patients. Methods: A total of 1086 patients who underwent PSMA PET-CT for staging or recurrence of prostate cancer were included. Total lesion volume (TLV) and total lesion upt
Context. The nuclear stellar disc (NSD) is a rotating, disc-like structure in the Galactic centre; it is believed to have a distinct star formation history and a predominantly old stellar population. However, its formation history and evolutionary links to other structures in the Galactic centre remain uncertain. Studying the chemical evolution of the NSD could provide new insights into this regio
Background: Although Kirsten rat sarcoma virus (KRAS) mutations represent the most frequent oncogenic driver alterations in Caucasian lung adenocarcinoma (LADC) patients, their impact on immune phenotype and tumor morphology is largely unexplored. Here, we investigated the associations between KRAS mutation subtypes, immune landscape, and tumor heterogeneity in surgically treated LADC, with a part
Purpose: Cancer affects a great number of people during working life, and tailored interventions targeting this population are important. The present study, focused on the developmental phase of a work-oriented intervention, aimed to describe work-related experiences and needs among people undergoing curative cancer therapy. Methods: People (n = 22, age md 55 years, range 39–64, purposive sampling
Objectives: This work aims to present epidemiological data on penile cancer from the Nordic region (Denmark, Finland, Iceland, Norway, Sweden) and discuss the results in light of the present knowledge and possible future treatment strategies. Patients and Methods: All patients diagnosed with penile cancer in the Nordic countries between 2000 and 2022 were identified in the NORDCAN database. Data o
The goal of the VAST challenge 2019 Mini Challenge 2 was to visualize radioactive contaminations measured by mobile and static sensors and their changes over time, allowing city officials to determine the severity of the leakage at the city's nuclear power plant. We propose cpmViz, a web-based tool that allows for interactive data exploration of the sensor readings in both of the spatial and tempo
BACKGROUND: Clinical guidelines recommend different revascularization strategies for nonculprit lesions in patients with ST-segment-elevation myocardial infarction (STEMI) versus non-STEMI (NSTEMI). Whether the prevalence of untreated high-risk vulnerable plaques differs in STEMI and NSTEMI and affects their outcomes is unknown. METHODS: In PROSPECT II (Providing Regional Observations to Study Pre
Incidence of early-onset (< 40 years) type 2 diabetes (T2D) is increasing. While multiple risk factors have been identified, particularly obesity and low socioeconomic status, early-life factors are hypothesised to play a role via fetal programming. We investigated sociodemographic and early-life factors in relation to early-onset T2D using a family-based design that accounts for shared genetic an
