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Ice-core timescales are vital for the understanding of past climate; hence they should be updated whenever significant amounts of new data become available. Here, the Greenland ice-core chronology GICC05 was revised for the last 3835 years by synchronizing six deep ice cores and three shallow ice cores from the central Greenland ice sheet. A new method was applied by combining automated counting o
Rationale: Galectin-3 (Gal-3) drives fibrosis during chronic lung injury, however, its role in acute lung injury (ALI) remains unknown. Effective pharmacological therapies available for ALI are limited; identifying novel concepts in treatment is essential. GB0139 is a Gal-3 inhibitor currently under clinical investigation for the treatment of idiopathic pulmonary fibrosis. We investigate the role
Diverse approaches such as oscillating gradients, tensor-valued encoding, and diffusion-relaxation correlation have been used to study microstructure and heterogeneity in healthy and pathological biological tissues. Recently, acquisition schemes with free gradient waveforms exploring both the frequency-dependent and tensorial aspects of the encoding spectrum b(ω) have enabled estimation of nonpara
This study tested for an association between early cancer-related biomarkers and low-to-moderate exposure to fumes from welding mild steel. Methods Male, non-smoking participants from southern Sweden were recruited and examined (N=338, 171 welders and 167 controls); of these, 78 welders and 96 controls were examined on two occasions six years apart. Exposure to welding fumes was evaluated by measu
To provide more integrated care, several countries have implemented the Flexible Assertive Community Treatment (FACT) model. However, this model does not guarantee full integration, especially in complex and fragmented service systems like in Norway. Hence, we investigated which barriers that might reduce the potential for integrated care in the Norwegian system, as described by staff in FACT team
This study explores the experiences of Swedish upper secondary school chemistry students working with a socioscientific issue about per- and polyfluoroalkyl substances (PFAS) in everyday products, and how they perceive that this teaching has influenced them in their role as citizens in a democratic society. Data collection has been carried out on several occasions over a period of one and a half y
Azo dyes are recalcitrant organic pollutants present in textile industry effluents. Conventional treatment methods to remove them come with a range of disadvantages. Nanoparticles and their nanocomposites offer more efficient, less expensive and easy to handle wastewater treatment alternative. Methods. In this study, nanoparticles of nickel oxide (NiO-NPs), copper oxide (CuO-NPs) and their nanocom
AMP-activated protein kinase (AMPK) activation is considered a useful strategy for the treatment of type 2 diabetes (T2D). It is unclear whether the expression and/or activity of AMPK in adipocytes is dysregulated in obesity. Also, the expression/activity pattern of AMPKβ isoforms, which are targets for AMPK activators, in adipocytes remains elusive. In this study we show that the two AMPKβ isofor
Results from the application of a new seismic technique for non-destructive testing of pavement layer moduli are presented. The method is based on the multichannel analysis of surface waves (MASW) method and multichannel simulation with one receiver (MSOR). The MSOR method uses one accelerometer (receiver), a light hammer (source), and a single-channel recording device to generate a simulated mult
The Baltic Sea is one of the fastest-warming marginal seas globally, and its temperature rise has adversely affected its physical and biochemical characteristics. In this study, forty years (1982–2021) of sea surface temperature (SST) data from the advanced very high resolution radiometer (AVHRR) were used to investigate spatial and temporal SST variability of the Baltic Sea. To this end, annual
Background: Preeclampsia (PE) is a “multifactorial syndrome” in which ambient air pollution may contribute to the etiology of PE. However, the underlying mechanism of this association is not clearly elucidated. This dissertation aims at understanding the placental molecular mechanism underlying the relationship of prenatal exposure to ambient air pollution with preeclampsia and fetal growth by cha
Kyrkspirorna och tornen på Stockholms horisont blandar sig med radiosändningar som flyger ut över staden bredvid privatiserade våglängder, driver ner genom atmosfären och sjunker ner i det övergivna underjordiska telefonsystemet. Stockholm har byggnader som funnits där i århundraden, men är också full av den mest moderna och samtida arkitektur. Allt konkurrerar om sin plats i det kollektiva minnetThe towers of the Stockholm skyline twine with radio transmissions, flying out over the city, drifting down through the streets and sinking into the underground telephone system below. Stockholm has buildings that have been there for centuries, but is also full of modern and contemporary architectures, all jostling for their place in parallel collective memory. In taking the city up as a subject,
