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Background: The fractional exhaled nitric oxide (FENO) test is a point-of-care test that is used in the assessment of asthma. Objective: To provide evidence-based clinical guidance on whether FENO testing is indicated to optimize asthma treatment in patients with asthma in whom treatment is being considered. Methods: An international, multidisciplinary panel of experts was convened to form a conse

Att fastställa byggnaders energiprestanda på ett rättvist och transparent sätt är viktigt.För att kunna fastställa en byggnads energiprestanda i drift och för att identifieraprestandaavvikelser behöver uppmätt energianvändning normaliseras. Detta görs genom att korrigera uppmätt energianvändning för avvikelser som förelegat vid mätning jämfört med de förutsättningar som antagits vid projektering.I

This comparative study explores how breaches can be applied to unveil potential blindspots within the social constructs surrounding design practice in Sweden and New Zealand. When in-depth interviews with designers in both countries were analysed, similarities and differences appeared. The underlying norms and values identified suggest that the two countries share a similar value-base in relation This comparative study explores how breaches can be applied to unveil potential blindspots within the social constructs surrounding design practice in Sweden and New Zealand. When in-depth interviews with designers in both countries were analysed, similarities and differences appeared. The underlying norms and values identified suggest that the two countries share a similar value-base in relation

In this article, we explore why solidarity has not worked according to expectation in EU migration and asylum law, and why it is unlikely to work in the future. First, we explore discourses of burden-sharing and solidarity in EU law from the 1990s up to the Lisbon treaty in 2009 to identify emergent path dependencies. This period saw the introduction of primary law provisions on solidarity, such a

OBJECTIVE: In Huntington's disease (HD), the disease-causing huntingtin (HTT) protein is ubiquitously expressed and causes both central and peripheral pathology. In clinical HD, a higher body mass index has been associated with slower disease progression, indicating that metabolic changes may be involved in disease pathogenesis. Underlying mechanisms of metabolic changes in HD are not fully known,

Huntington disease (HD) is a fatal neurodegenerative movement disorder caused by an expanded CAG repeat in the huntingtin gene (HTT). The mutant huntingtin protein is ubiquitously expressed, but only certain brain regions are affected. The hypothalamus has emerged as an important area of pathology with selective loss of neurons expressing the neuropeptides orexin (hypocretin), oxytocin and vasopre

This book falls within the scope of the ASILE Project. ASILE studies the interactions between emerging international protection systems and the United Nations Global Compact for Refugees (UN GCR), with particular focus on the EU’s role. It examines the characteristics of international and country-specific asylum governance instruments and arrangements, and their compatibility with international an

This study aimed to analyze stressors to which medical staff is vulnerable due to the coronavirus disease 2019 (COVID-19) pandemic. It also imposes a hierarchy on complex relations among stressors for excavating underlying structure and builds a model of interrelationships contrasting reality. The design of this study comprises a literature survey, data collection from primary sources, and analysi

Background: Many ice hockey goaltending techniques force hip joints and groin muscles into extreme ranges of motion, which may increase the risk of hip and groin problems. Purpose: To explore how elite goaltenders and goaltending coaches perceive the demands of common goaltending techniques on the hip and groin region. We further explored differences in perception between goaltenders and their coa

The spatio-temporal scale of design for sustainability has come full circle. What started within a technology-oriented global outlook, later evolving into a people-oriented and local view on change, now urges for a holistic, broad extent and multilevel design for sustainability. This paper enquires into the theories of social change that govern different approaches within the field, and positions

Xenotransplantation is a potential solution for the severe shortage of human donor organs and tissues. The generation of humanized animal models attenuates strong innate immune responses, such as complement-mediated hyperacute rejection. However, acute vascular rejection and cell mediated rejection remain primary barriers to xenotransplantation, which limits its clinical application. In this study