Investigations on tyrosinase and a tyrosinase related protein
Tyrosinase and tyrosinase-related protein-1 are enzymes involved in melanin synthesis and specific to the melanocyte and the melanoma cell. In the studies upon which this thesis is based, these enzymes were investigated in normal melanocytes, cultured human melanoma cells and transfected mouse fibroblasts. Tyrosinase was isolated from cultured melanoma cells and from bovine eye preparations, and t
