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The consumption of alcoholic beverages has wide effects, for example, causes premature mortality, prevents certain heart diseases, increases crime rates, and affects quality of life. The main problems with alcohol consumption from an economic point of view are lack of information for consumers when making consumption decisions, externalities, and the addictive nature. It is expected that this resu
Popular Abstract in Swedish De flesta cancerpatienter dör på grund av spridning av tumörceller till olika organ. Invasiv och metastaserande cancer svarar ofta inte på behandling och blir då i många fall dödlig. Leukemi är en elakartad sjukdom av blodceller, som påverkar blod-producerande organ. Den höga förekomsten av leukemi förekommer i äldre befolkningen och hos barn. Leukemi återfall och resiThe majority of current treatments used for treatment of prostate cancer (PCa) and leukemia are often limited to a narrow subsets of treated patients. As such, there still remains a significant scope for gaining deeper understanding of molecular mechanisms underlying cancer metastasis for improvement of targeted treatment. Elevated expression of a cell cycle regulator cyclin A1 initiated leukemia
Popular Abstract in Swedish Avsikten med denna avhandling är att förstå de viktiga begreppsmässiga och operativa utmaningar som internationella biståndsgivare, liksom offentliga och privata institutioner, möter när man utformar och genomför alternativa former av sociala bostadsfinansiering som skall vara inkluderande för den fattiga urbana befolkningen. Avhandllingen försöker besvara tre frågor, bThe purpose of the thesis is to further understand key conceptual and operational challenges that international aid donors, and public and private institutions, face while designing and implementing alternative forms of social housing finance which aim to be inclusive for the urban poor. Based on an in-depth study of the work of the Foundation for the Promotion of Local Development (PRODEL) in thr
Languages differ with respect to which element they select as the subject in passive of ditransitive verbs: either the active indirect object (the goal argument) or the active direct object (the theme argument). In standard American English, e.g., only the goal argument may be promoted, as shown by the difference between (1b) and (1c). (1) a. John gave Mary a red bike yesterday. b. Mary was give
DNA-dependent protein kinase (DNA-PK) is a holoenzyme consisting of a regulatory subunit, the heterodimeric Ku70/86, and a catalytic subunit known as DNA-dependent protein kinase catalytic subunit (DNA-PKcs). DNA-PK takes part in a number of cellular functions including growth control, immunoglobulin gene rearrangement and DNA repair. The Ku86 subunit of DNA-PK has been reported to exist in human
BACKGROUND: Interactive behavior change technology (eg, computer programs, Internet websites, and mobile phones) may facilitate the implementation of lifestyle behavior interventions in routine primary health care. Effective, fully automated solutions not involving primary health care staff may offer low-cost support for behavior change. OBJECTIVES: We explored the effectiveness of an electronic
Background. Current evidence suggests that high red meat intake is associated with increased colorectal cancer risk. High fish intake may be associated with a decreased risk, but the existing evidence is less convincing. Methods: We prospectively followed 478040 men and women from 10 European countries who were free of cancer at enrollment between 1992 and 1998. Information on diet and lifestyle w
Popular Abstract in Swedish Inom de flesta sociologiska forskningsperspektiv tillskrivs mellanmänsklig interaktion avgörande betydelse för att förstå olika aspekter av det sociala livet. I denna studie ligger emellertid fokus på den praktiska och erfarenhetsmässiga relationen mellan människor och ting ? en relation med stor betydelse för individers identitet och sociala liv. Detta är ett ofta bortIn most sociological paradigms the importance of human interaction for the understanding of societies, is a well established fact. In this study, the focus is the interaction between human beings and material things as it is occurring in practice. Such an approach with its important consequences for understanding both social life and self, is often overlooked in studies within the field of sociolo
This thesis work is concerned with the efficient layout and operation of substations, i.e. those district heating (DH) system units which connect the network and internal building heating systems, such as radiator heating systems and domestic hot water distribution networks. The ambition was to make realistic investigations closely related to practical technologies within the field. The themes of
Popular Abstract in Swedish Den fysiska grunden för fysiska aktionsverbThis work is a study of verbal semantics with a focus on the discussion and illustration of the role of body parts and the semantic incorporation into verbal roots of the actions that involve various body parts. Following a general discussion of the basic issues of language construction and human body actions with the image schemas of force-dynamics presented in line with the framework of cognitiv
Popular Abstract in Swedish Denna studie handlar om mediereception som pedagogisk form och meningsskapande över tid. Jag är intresserad av att förstå komplexitet i meningsskapande processer som utgår från medieproduktioner. Syftet med avhandlingen är att undersöka vad mötet mellan en grupp lärarstudenter och deras texter kan erbjuda för möjligheter och begränsningar för meningsskapande över tid i The present study is about media reception as an educational form, supporting meaning-making over time. The thesis stems from the desire to understand the complexity in a meaning-making process that takes its point of departure in media productions. The aim is to investigate the possibilities and limitations for meaning-making over time, afforded by the meeting of a group of student teachers and t
Popular Abstract in Swedish Datorgenererade bilder är en viktig del av underhållningsindustrin, som bland annat innefattar spel- och filmindustrin. För att kunna skapa avancerade specialeffekter i filmer samt stora och detaljerade spelvärldar krävs datorprogram som utnyttjar beräkningskraften i dagens datorer på ett effektivt sätt. Bättre och snabbare datorprogram leder ofta till nya användaruppleComputer generated imagery is vital to the entertainment industry in the production of games and films, for example. It is also increasingly important for visualization in design, architecture, engineering, and medicine, to name a few. Improvements to rendering techniques come from a combination of improved algorithms and more powerful hardware. Typically, hardware developments introduce new chall
Reglerna om näringsbetingade andelar medger skattefrihet på utdelning och kapitalvinst. Genom lagstiftning 2003 utvidgades regelverket som tidigare endast hade omfattat utdelning under vissa givna förutsättningar, till att även omfatta kapitalvinster. Syftet med regeländringen var framför allt att undvika kedjebeskattning i bolagssektorn. En andel är näringsbetingad om den ägs av en association soUnder the Swedish participation exemption regime, dividends and capital gains are tax-exempt under the assumption that the shares are held for business reasons. Shares will be considered held for business reasons provided that the holding meets certain requirements while the shares are held in either a corporation or an economic association. The purpose behind the participation exemption regime is
Lately, there has been a world-wide increase in the awareness of animal cruelty e.g. in the entertainment business, meat industry, in the scientific community, and among people in general. This has called for a scrutiny of how we treat animals and in the scientific community it has stimulated research to reduce animal experiment. Experimental systems usually considered animal cruelty free, like ce
Few business models are as hyped right now as the Software as a Service (SaaS) model. But how sustainable is it? In the last decade, SaaS has reshaped the software industry and has become a leading delivery model of B2B enterprise software. During this period, the disruptors that pioneered the model and the incumbents that transitioned to it have created tremendous shareholder value. However, the
Barn i svenska förskolor utsätts för höga ljudnivåer som kan orsaka hörselskador och röstrelaterade problem bland både lärare och elever. Detta på grund av att de behöver höja rösten för att göra sig hörda i en bullrig miljö. På grund av detta är det av intresse att på något sätt kunna förutse ljudmiljön i just förskolor. Detta kan exempelvis göras genom att falta binaurala inspelningar av förskolChildren in Swedish preschools are exposed to high noise levels that can cause hearing damage or voice related problems among both teachers and students, this since they have to raise their voice in order to make themselves heard in a noisy environment. Because of this it is of interest to be able to predict the sound environment in preschools. A way to do this is through convolving binaural recor
ABSTRACT Already in 1960, the Harvard professor Theodore Levitt concluded that without the capabilities to adapt, companies risk missing imminent trends and changes in the market and could suddenly be outrun by competitors. The subject of business model adaption has since been heavily discussed and is, if possible, of even greater importance today. With this thesis, the authors aspires to cast lig
Background BIM, Building Information Modelling, is a relatively new approach to work with building design and information management within the building industry. As higher demands are placed on product information and information management, manufacturers of building materials have to meet the need for BIM objects and 3D modeling. Ecophon is a supplier of sound absorbing ceilings and wall absorbe
Certain organic micropollutants and emerging contaminants are increasingly detected in wastewater effluents due to enhancement of detection techniques and new technological processes or household items being introduced. Some of them can accumulate in food chains and/or pose health risks for humans, wildlife and ecosystems. Often, these are very difficult or impossible to sufficiently remove using
I december 2022 blev en polis allvarligt skadad i samband med ett ingripande. Den kvinnliga polisen blev biten och fick motstå upprepande slag mot huvudet. 27 februari 2023 blev en polis i Norrköping överfallen med kniv utanför polishuset. Detta är bara två av flera incidenter där poliser blir offer för våld och hot om våld i deras yrkesutövning. Poliser tillhör en yrkesgrupp som till vardags fårIn December 2022, a police officer was seriously injured in connection with an intervention. The female police officer was bitten and had to with-stand repeated blows to the head. On February 27, 2023, a police officer in Norrköping was attacked with a knife outside the police station. These are just two of several incidents where police officers are victims of violence and threats of violence in
