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A Nationwide Cohort Study of Outcome after Pediatric Appendicitis

Introduction Children with appendicitis often present with complicated disease. The aim of this study was to describe the clinical management of pediatric appendicitis, and to report how disease severity and operative modality are associated with short- and long-term risks of adverse outcome. Materials and Methods A nationwide retrospective cohort study of all Swedish children (<18 years) diagnose

From Lock-In to Phase-Out : Pathways Towards Fossil Fuel Subsidy Reform

Denna avhandling undersöker de politiska orsakerna till reformer av subventioner av fossila bränslen i OECD-länderna mellan 2009 och 2023. Trots att subventioner för fossila bränslen är allmänt erkända som ekonomiskt ineffektiva och miljöskadliga, är de fortfarande djupt rotade, där OECD-länderna tillsammans upprätthåller ett årligt stöd på cirka 100 miljarder US-dollar. Avhandlingen behandlar fråThis dissertation investigates the political determinants of fossil fuel subsidy reform in OECD countries between 2009 and 2023. Despite widespread recognition of their economic inefficiency and environmental harm, fossil fuel subsidies remain entrenched, with OECD countries collectively sustaining around USD 100 billion in annual support. The research addresses why some governments successfully r

Crystal-to-Crystal Transitions in Binary Mixtures of Soft Colloids

In this article, we demonstrate a method for inducing reversible crystal-to-crystal transitions in binary mixtures of soft colloidal particles. Through a controlled decrease of salinity and increasingly dominating electrostatic interactions, a single sample is shown to reversibly organize into entropic crystals, electrostatic attraction-dominated crystals, or aggregated gels, which we quantify usi

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https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/slu/nyhetsbrev/nyhetsbrev_2023-4.pdf - 2026-05-24

Overcoming Immune Evasion in Staphylococcus aureus : Strategies for Rational Vaccine Design.

Staphylococcus aureus remains one of the most elusive targets in bacterial vaccinology, primarily due to its complex immune evasion strategies and the phenomenon of immune imprinting. Despite decades of research and numerous clinical trials, no vaccine has demonstrated protective efficacy in humans. This review examines the underlying reasons for these failures and proposes a rational, integrativ

Identification of a novel gene associated with group B Streptococcus persister cell formation and biofilm production

Antibiotic persistence arises when a subset of cells in an otherwise susceptible bacterial population temporarily exhibits elevated tolerance to bactericidal antibiotics. While significant progress has been made in elucidating persister mechanisms, much of this research has focused on Gram-negative bacteria, and these findings are not always applicable to Gram-positive species. This study explores

Collisions without sight: head acceleration in blind football and implications for sport-related concussion

IntroductionSport-related concussion (SRC) is a pressing issue in Para sport, yet biomechanical mechanisms remain poorly understood. Athletes with visual impairment face elevated risks due to sport-specific demands, such as frequent collisions in blind football. This pilot study examined head acceleration responses in blind football players compared with non-disabled football players, and between

Capsule and PspA Cooperatively Confer Resistance of Streptococcus pneumoniae to the Human Defensin HNP-1

Streptococcus pneumoniae resists host defenses through multiple surface factors, yet their specific contribution to protection against antimicrobial peptides remains incompletely understood. We examined the role of pneumococcal surface protein A (PspA) and the polysaccharide capsule in protection against the human defensin HNP-1. PspA conferred increased resistance to HNP-1-induced killing, shown

Reimagining the Capitalocentric Present : Unpacking Fantasies of Ethical Consumption: Introducing new Consumer Ethics, and Establishing Sustainable Visions

In this conceptual paper we reimagine the Capitalocentric present. To do so, we (1) critique corporate fantasies about ethical consumption; (2) offer alternative relational ethics of consumption, with special attention to concrete neo-animist practices to imagine alternative futures to the Capitalocentric present, and (3) invite imaginative theorization as a bridge between present and future.In this conceptual paper we reimagine the Capitalocentric present. To do so, we (1) critique corporate fantasies about ethical consumption; (2) offer alternative relational ethics of consumption, with special attention to concrete neo-animist practices to imagine alternative futures to the Capitalocentric present, and (3) invite imaginative theorization as a bridge between present and future.

Impact of Functional Models in a Decision Context of Critical Infrastructure Vulnerability

Critical infrastructures provide essential services for the functioning of the society, and disruption of these services can lead to large-scale consequences. Hence, it is of utmost importance to analyze the vulnerability of critical infrastructures and use the results to guide decisions of improving their robustness towards strains. Since real-life critical infrastructures can be regarded as comp

Whole genome sequencing in early onset advanced heart failure

The genetic contributions to early onset heart failure (HF) are incompletely understood. Genetic testing in advanced HF patients undergoing heart transplantation (HTx) may yield clinical benefits, but data is limited. We performed deep-coverage whole genome sequencing (WGS) in 102 Swedish HTx recipients. Gene lists were compiled through a systematic literature review. Variants were prioritized for

Effect of encapsulated protein on the dynamics of lipid sponge phase: a neutron spin echo and molecular dynamics simulation study

Lipid membranes are highly mobile systems with hierarchical, time and length scale dependent, collective motions including thickness fluctuations, undulations, and topological membrane changes, which play an important role in membrane interactions. In this work we have characterised the effect of encapsulating two industrially important enzymes, β-galactosidase and aspartic protease, in lipid spon

Structure and anisotropic dynamics of stimuli responsive colloidal ellipsoids at the nearest neighbor length scale

Stimuli-responsive self-assembly of (an) isotropic colloids has resulted in a plethora of self-assembled structures with potential applications in fabricating smart materials. A lack of detailed understanding of the interplay between these self-assembled structures and the resulting dynamics has often impeded the exploitation of their full potential. Herein, we have unveiled the relationship betwe