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BACKGROUND: CXC chemokines are induced by inflammatory stimuli in epithelial cells and some, like MIG/CXCL9, IP-10/CXCL10 and I-TAC/CXCL11, are antibacterial for Streptococcus pyogenes. METHODOLOGY/PRINCIPAL FINDINGS: SpeB from S. pyogenes degrades a wide range of chemokines (i.e. IP10/CXCL10, I-TAC/CXCL11, PF4/CXCL4, GROalpha/CXCL1, GRObeta/CXCL2, GROgamma/CXCL3, ENA78/CXCL5, GCP-2/CXCL6, NAP-2/C

Together with response time the force of responses to stimuli can provide important clues about cognitive and affective processes. However, while there has been much discussion of factors involved in the accurate measurement of response time (RT), key issues and assumptions in assessment of response force (RF) have been far less studied. Here, hierarchical Bayesian analysis is used to examine the

The quality in the exchange of technical data in the extended enterprise is mainly defined by the geometrical consistence of the transferred information. Methods and definitions that cover the remaining aspects of data exchange have to be developed. This article discusses a new standardization effort for the exchange management of technical data (ENGDAT version 3) and provides a methodology as wel

Wearable medical devices can be positioned around the torso for monitoring of critical health parameters. The signal transmission between them is through a wireless link over an on-body propagation channel. In this paper, the effect of some factors which could influence the propagation channel around the torso as: (a) frequency of operation (b) positions of the arms (c) material of a chair used, h

The aim of the present doctoral thesis is to study and conceptualize juridification as a phenomenon. This aim comprises analyzing the theories through which juridification as an empirical development is interpreted. In this thesis juridification signifies displacements towards legal discourse. Juridification comes about when an issue that was previously dealt with within a cultural, ethical, polit

We present a method for the estimation of the distribution of the quasi-static hogging-bending moment for a floating body. Starting points of this study are temporal characteristics of the sea state. The approximation is deduced from the estimation of the joint distribution of crest amplitude and crest length. The quality of the model is investigated by comparing computed distributions with empiri

The increasing rate of caesarean delivery is a worldwide concern. A major contributor to this evolution has been a concomitantly decline in vaginal birth after caesarean, because of the risk of intrapartum uterine rupture, which is a rare but potentially catastrophic complication of a trial of labour after caesarean (TOLAC). On the other hand, elective repeat caesarean is associated with surgical

In the last decades one of the main topics in the international intellectual property forum has been the biopiracy issue. Genetic resources and traditional knowledge from developing nations are being misappropriated (i.e. biopiracy), by commercial actors in order to receive patent protection. Developments in genetics and biotechnology have intensified the controversy and attempts were initially so

This thesis offers a holistic perspective on the phenomenon of embodying Otherface. It provides a deeper insight into the categories Transface and Cripface, the latter being a term for an able person depicting a person with visible or invisible disabilities, also referred to as cripping up. The thesis sums up the plight for rights and acceptance whilst looking at the problems involved with authent

Objective: Develop a generic trans-disciplinary, skills-based capability framework for health professionals providing care for people with OA. Design: e-Delphi survey. An international inter-professional Delphi Panel (researchers; clinicians; consumer representatives) considered a draft framework (adapted from elsewhere) of 131 specific capabilities mapped to 14 broader capability areas across fou

The establishment of a database has been suggested in order to collect, organize, and distribute genetic information about esophageal cancer. The World Organization for Specialized Studies on Diseases of the Esophagus and the Human Variome Project will be in charge of a central database of information about esophageal cancer–related variations from publications, databases, and laboratories; in add

The Swedish legal scholar Tore Strömberg (1912-1993) is often characterized as the last true representative of the Uppsala school of legal thinking.

The manipulation of jets has since long been subject to research, due to the wide range of industrial applications in which they are used. A vast number of numerical and experimental studies concerning the physics of the breakup process of continuous jets have been published. Improvements in mixing and ambient gas entrainment have been reported experimentally when using intermittent injection, alt

OBJECTIVE: The microenvironment of colon cancer (CC) is heterogeneous including cells of myeloid lineage affecting tumor growth and metastasis. Two functional subtypes of myeloid cells have been identified; one (M1) is tumor-inhibitory and the other one (M2) is tumor-promoting. Whether the three myeloid markers EMR1, CD206 and CD86 are expressed only in the infiltrating myeloid cells or also in th