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Inhibition of coxsackie B virus infection by soluble forms of its receptors: Binding affinities, altered particle formation, and competition with cellular receptors

We previously reported that soluble decay-accelerating factor (DAF) and coxsackievirus-adenovirus receptor (CAR) blocked coxsackievirus 133 (CVB3) myocarditis in mice, but only soluble CAR blocked CVB3-mediated pancreatitis. Here, we report that the in vitro mechanisms of viral inhibition by these soluble receptors also differ. Soluble DAF inhibited virus infection through the formation of reversi

Tomas Hellström

Professor Kontaktinformation E-post: tomas [dot] hellstrom [at] fek [dot] lu [dot] se Telefon: +46 46 222 80 27Organisation Strategi Rumsnummer: Alfa 5,6 rum B423 Hämtställe: 10 WebbplatsTomas Hellströms profil i Lunds universitets forskningsportalAndra roller Facklig förtroendeman ST vid Lunds universitet Professor CIRCLE Publikationer Visar av publikationer. Sorterade efter år och sen titel. Fil

https://www.ehl.lu.se/tomas-hellstrom - 2026-05-23

STATISTICAL ANALYSIS OF EXTREME SEA WATER LEVELS AT THE FALSTERBO PENINSULA, SOUTH SWEDEN

Falsterbo Peninsula on the south coast of Sweden is low-lying and exposed to flooding. In 1872 the extreme storm surge Backafloden caused large devastation on the Swedish, Danish, and German coasts in the South Baltic Sea. For the Falsterbo Peninsula, the peak storm surge level is estimated to have been 240 cm above normal. If a similar event happened today, the consequences would be far worse, as

Changes in resting-state functional connectivity after stroke in a mouse brain lacking extracellular matrix components

In the brain, focal ischemia results in a local region of cell death and disruption of both local and remote functional neuronal networks. Tissue reorganization following stroke can be limited by factors such as extracellular matrix (ECM) molecules that prevent neuronal growth and synaptic plasticity. The brain's ECM plays a crucial role in network formation, development, and regeneration of the c

Making Analogues of Tröger's Base – Fused oligomers, endo/exo isomers and twisted amides

The centenarian Tröger’s base (TB) was envisaged as scaffold for the construction of tubular-shaped cleft molecules due to its the remarkable structural properties. This endeavor started with the synthesis of the three possible diastereomers of a linear symmetrically fused tris-TB analogue, the anti-anti, the syn-syn, and the syn-anti. All three diastereomers showed unprecedented stability to acid