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Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status.
Gene expression analyses were performed on 121 consecutive childhood leukemias (87 B-lineage acute lymphoblastic leukemias (ALLs), 11 T-cell ALLs and 23 acute myeloid leukemias (AMLs)), investigated during an 8-year period at a single center. The supervised learning algorithm k-nearest neighbor was utilized to build gene expression predictors that could classify the ALLs/AMLs according to clinical
Expression of somatostatin receptor subtypes 2 and 4 in human benign prostatic hyperplasia and prostatic cancer.
BACKGROUND: The presence of receptor subtypes for the inhibitory peptide somatostatin in prostatic tissue has been a controversial issue with conflicting reports. To elucidate whether prostatic epithelial cells express mRNA for somatostatin receptor (SSTR) subtype 2 and 4, we have investigated the localization of SSTR2 and SSTR4 transcripts in prostatic tissues by in situ hybridization. METHODS: N
A population-based investigation of the autoantibody profile in mothers of children with atrioventricular block.
The objective of the study was to investigate the antigen specificity and occurrence of individual autoantibodies in mothers of children diagnosed with atrioventricular (AV) block in a nation-wide setting. Patients with AV block detected before 15 years of age were identified using national quality registries as well as a network of pediatric and adult cardiologists and rheumatologists at the six
Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain.
Bruton's agammaglobulinemia tyrosine kinase (Btk) is a cytoplasmic tyrosine kinase important in B-lymphocyte development, differentiation, and signaling. Btk is a member of the Tec family of kinases. Mutations in the Btk gene lead to X-linked agammaglobulinemia (XLA) in humans and X-linked immunodeficiency (Xid) in mice. Activation of Btk triggers a cascade of signaling events that culminates in t
Incidence of tuberculosis and early mortality in a large cohort of HIV infected patients receiving antiretroviral therapy in a tertiary hospital in Addis Ababa, Ethiopia
Preceding studies on morbidities and mortalities associated with TB in a cohort of HIV care indicate high incidence of TB development and premature death among patients on highly active antiretroviral treatment (HAART). This study aims to measure the rate of TB, TB mortality, and associated risk factors following commencement of HAART in a cohort of patients attending HIV care in Ethiopia. Patient
Short-term exposure to ambient particle gamma radioactivity is associated with increased risk for all-cause non-accidental and cardiovascular mortality
BACKGROUND: Recent studies have found that particulate matter (PM) attached radioactivity was associated with certain adverse health effects including increased blood pressure and lung dysfunction. However, there has been no investigation on the direct effect of PM radioactivity on mortality.METHODS: Exposures to ambient PM gamma activities were determined using U.S. EPA RadNet data. Data on daily
EMA Review of Daratumumab (Darzalex) for the Treatment of Adult Patients Newly Diagnosed with Multiple Myeloma
The use of daratumumab in combination with established regimens for the treatment of newly diagnosed multiple myeloma has recently been authorized by the European Medicines Agency based on results from three separate phase III randomized, active controlled, open-label studies that have confirmed enhanced efficacy and tolerability in both transplant-ineligible (MMY3008 and MMY3007) and transplant-e
DIAGNOSTIC RELIABILITY OF MEASUREMENT OF PREMATURE VENTRICULAR COMPLEX FREQUENCY RELATED TO DURATION OF AMBULATORY MONITORING
Background Premature ventricular complexes (PVCs) are generally quantified using a 24h ECG recording, but the diagnostic accuracy is unknown. We aimed to determine the day-to-day variability and optimal monitoring duration for PVC measurements among patients with frequent PVCs. Methods We included all patients who underwent a clinical ambulatory ECG recording lasting 25-30 days, using the PocketEC
T-cell receptor repertoire in human germinal centres
A search for an antigen-driven expansion of T lymphocytes in the inflamed joints in rheumatoid arthritis (RA) patients have been going on for decades. We here analyzed the human germinal centre T-cell receptor (TCR) Vbeta gene usage with polymerase chain reaction (PCR) combined with sequence analysis, to address the question of clonality in tonsils and synovial tissue from RA patients. Our data sh
Change in the Th1/Th2 phenotype of memory T-cell clones from rheumatoid arthritis synovium
The stability of established memory T helper (Th)1/Th2 cells in chronic inflammatory diseases is not clear, and a shift of the cytokine balance could control chronic inflammation. In order to study the regulation of the Th phenotype of memory T cells, polyclonal T-cell lines and clones with a Th1, Th0 or Th2 phenotype were developed from rheumatoid synovial tissue. Th1 [interleukin (IL)-12 + anti-
The GALAH survey : Characterization of emission-line stars with spectral modelling using autoencoders
We present a neural network autoencoder structure that is able to extract essential latent spectral features from observed spectra and then reconstruct a spectrum from those features. Because of the training with a set of unpeculiar spectra, the network is able to reproduce a spectrum of high signal-to-noise ratio that does not show any spectral peculiarities, even if they are present in an observ
Riktlinjer för internrevisionen vid Lunds universitet. Beslut 2023-02-17.
Lägg till titel Sida 1 av 6 Universitetsstyrelsen BESLUT Diarienummer STYR 2023/209 Datum 2023-02-17 Riktlinjer för internrevisionen vid Lunds universitet Inledning Myndighetens styrelse ska enligt 10 § internrevisionsförordning (2006:1228) besluta om riktlinjer (instruktion) för internrevisionen. Internrevisionsförordningen och Ekonomistyrningsverkets (ESV:s) föreskrifter samt dessa riktlinjer re
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Year in Review 2020 YEAR IN REVIEW - 2020 AT RWI FAIR AND EFFICIENT JUSTICE This is RWI RWI Around the World Looking Back at 2020: A Note from Morten Kjaerum, RWI Director A Note from the Programme Director External Assesments: What We Achieved in Kenya, Zimbabwe, and Turkey Belarus in Review: Summurasing Ten Years of Activities RWI Africa Programmes: Our New Director Shares Highlights RWI Cambodi
https://rwi.lu.se/wp-content/uploads/2021/06/YIR-2020-FINAL-Digital-version.pdf - 2026-05-23
Årsredovisning IT-enheten, 2012
Årsredovisning IT-enheten, 2012 Årsredovisning IT-enheten 2012 Årsredovisning, IT-enheten 2012 2 INNEHÅLL Året som har gått ................................................................. 3 Vår verksamhet ................................................................... 4 Avslutade projekt ................................................................ 5 Grundutbildning ......................
https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Fakulteterna/Arsredovisning_IT-enheten_2012.pdf - 2026-05-23
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Arkitektutbildning: utbildningsplan Arkitektutbildning Programkod: TAARK Omfattning: 300 högskolepoäng Tillträdesnivå: Grundnivå Beslutsfattare: Programledning A Utbildningsplanens giltighet: 2020/2021 Utbildningsplanen fastställd: 2020-02-17 Förutom utbildningsplanen för denna utbildning gäller även ge- mensamma föreskrifter och information för LTH. 1 Syfte och mål 1.1 Syfte Arkitektur handlar om
https://www.student.lth.se/fileadmin/lth/utbildning/studiehandboken/20_21/A_Uplan_20-21.pdf - 2026-05-23
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Masterutbildning i katastrofriskhantering och klimatanpassning: utbildningsplan Masterutbildning i katastrof- riskhantering och klimat- anpassning Programkod: TAKAK Omfattning: 120 högskolepoäng Tillträdesnivå: Avancerad nivå Beslutsfattare: Programledning BI/RH Utbildningsplanens giltighet: 2020/2021 Utbildningsplanen fastställd: 2020-02-05 Förutom utbildningsplanen för denna utbildning gäller äv
https://www.student.lth.se/fileadmin/lth/utbildning/studiehandboken/20_21/MKAT_Uplan_20-21.pdf - 2026-05-23
About Raoul Wallenberg - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law
About Raoul Wallenberg - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Me
https://rwi.lu.se/about/about-raoul-wallenberg/ - 2026-05-23
RWI Cooperation with NHRIs in Asia - The Raoul Wallenberg Institute of Human Rights and Humanitarian
RWI Cooperation with NHRIs in Asia - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Progr
https://rwi.lu.se/rwi-cooperation-with-nhris-in-asia/ - 2026-05-23
Microsoft Word - SOC_Master_of_Science_in_System-on-Chip.doc
Microsoft Word - SOC_Master_of_Science_in_System-on-Chip.doc Masterutbildning i system på chips: utbildningsplan 1 Master of Science in System-on- Chip Study programme valid from: 2007/08 Study programme approved: 2007-08-15 In addition to the study programme for the Master of Science in System-on-Chip, the general regulations for and information from the Faculty of Engineering at Lund University
https://www.student.lth.se/fileadmin/lth/english/master/SOC_Master_of_Science_in_System-on-Chip.pdf - 2026-05-23