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Causal nature of neighborhood deprivation on individual risk of coronary heart disease or ischemic stroke : A prospective national Swedish co-relative control study in men and women

We studied the association between neighborhood socioeconomic status (SES) and incidence of coronary heart disease (CHD) or ischemic stroke in the total population and in full- and half-siblings to determine whether these associations are causal or a result from familial confounding. Data were retrieved from nationwide Swedish registers containing individual clinical data linked to neighborhood of

Association between Childhood Obesity and Neighbourhood Accessibility to Fast-Food Outlets : A Nationwide 6-Year Follow-Up Study of 944,487 Children

Objectives: The aim of this 6-year follow-up study was to examine whether neighbourhood accessibility to fast-food outlets was associated with diagnosed childhood obesity, after adjustment for neighbourhood- and individual-level socio-demographic factors. Methods: This 6-year follow-up study comprised 484,677 boys and 459,810 girls aged 0-14 years in Sweden. The follow-up period ran from January 1

Mortality in patients with atrial fibrillation and common co-morbidities – a cohort study in primary care

Objective: To study the association between cardiovascular co-morbidities and mortality risk in primary care patients with atrial fibrillation. Methods: The study population included all adults (n = 12,283) ≥ 45 years diagnosed with AF at 75 primary care centres in Sweden between 2001 and 2007. The outcome was mortality (until 2010) and data were explored for co-morbidities using Cox regression wi

Militarisering av Åland – möjlighet, eller brott mot internationell rätt?

Säkerhetsläget i Europa har förändrats drastiskt under de senaste åren, med de två största förändringarna i Rysslands invasion av Ukraina, och NATO:s expandering med Sverige och Finland som nya medlemsstater. Den ökade militariseringen i Europa har också resulterat i att en gammal fråga nu igen dykt upp i den allmänna debatten, nämligen frågan om Åland borde remili-tariseras i syfte att säkra ÖsteThe security in Europe has changed dramatically during recent years, with the two most significant changes being Russia’s invasion of Ukraine, and NATO:s expansion with Sweden and Finland as new member states. The increasing militarization in Europe has also brought back an old question into the public debate, namely if the Åland islands should be re-militarized with the purpose of securing the Ba

En säkerhetspolitisk vändpunkt

Denna uppsats ämnar till att bilda en förståelse för hur Rysslands fullskaliga invasion av Ukraina har påverkat EU:s säkerhetspolitik, med fokus på dels hur EU själva definierar det förändrade säkerhetspolitiska läget och hur de utifrån det förändrade läget har valt att agera. Den metodologiska utgångspunkten för att besvara detta sker genom en kvalitativ innehållsanalys av dokument från EU såsom

Maternal half-sibling families with discordant fathers : A contrastive design assessing cross-generational paternal genetic transmission of alcohol use disorder, drug abuse and major depression

BackgroundWe introduce and apply an elegant, contrastive genetic-epidemiological design - Maternal Half-Sibling Families with Discordant Fathers - to clarify cross-generational transmission of genetic risk to alcohol use disorder (AUD), drug abuse (DA) and major depression (MD).MethodUsing Swedish national registries, we identified 73 108 eligible pairs of reared together maternal half-siblings an

J-curve association between alcohol intake and varicose veins in Japan : The Shimane CoHRE Study

The effect of alcohol intake on varicose veins (VV) has not been determined by its consumption level. The aim of this study was to investigate the association between alcohol intake and VV in an elderly general population. Using a cross-sectional approach, the Shimane CoHRE Study data, comprising a total of 1060 participants, were analyzed. By multivariate regression analysis adjusted with basic c

Problematic Internet Use and Child-To-Parent Violence: Associations Between Social Media Use, Gaming, and Abusive Behaviours Toward Parents

Problematic internet use (PIU) has been linked to adverse outcomes in adolescence, but its association with child-to-parent violence (CPV) has rarely been examined. This study investigated whether problematic social media use and problematic gaming were associated with CPV in a school-based sample of Swedish adolescents and young adults. In bivariate analyses, both PIU domains showed dose-responseProblematic internet use (PIU) has been linked to adverse outcomes in adolescence, but its association with child-to-parent violence (CPV) has rarely been examined. This study investigated whether problematic social media use and problematic gaming were associated with CPV in a school-based sample of Swedish adolescents and young adults. In bivariate analyses, both PIU domains showed dose-response

Pattern of Risks for Psychiatric and Substance Use Disorders in the Offspring of Parents With Alcohol Use Disorder

OBJECTIVE: The authors sought to clarify the components of the familial liability to alcohol use disorder (AUD) by examining parent-offspring transmission in a large Swedish population sample. METHODS: To this end, 1,244,516 offspring in intact families with a mean age at follow-up of 37.7 years (SD=6.8) were examined. Hazard ratios for offspring of parents with AUD were calculated using Cox model

Role of the polyamine transporter PotABCD during biofilm formation by Streptococcus pneumoniae

Streptococcus pneumoniae is a bacterium of great global importance, responsible for more than one million deaths per year. This bacterium is commonly acquired in the first years of life and colonizes the upper respiratory tract asymptomatically by forming biofilms that persist for extended times in the nasopharynx. However, under conditions that alter the bacterial environment, such as viral infec

HAMLET, a human milk protein-lipid complex, modulates amoxicillin induced changes in an ex vivo biofilm model of the oral microbiome.

Challenges from infections caused by biofilms and antimicrobial resistance highlight the need for novel antimicrobials that work in conjunction with antibiotics and minimize resistance risk. In this study we investigated the composite effect of HAMLET (human alpha-lactalbumin made lethal to tumor cells), a human milk protein-lipid complex and amoxicillin on microbial ecology using an ex vivo oral

Lifestyled Business Practices : The entanglement of consumption and business in criminal gangs

The entanglement of business and consumption practices have been neglected in prior consumer research. We address this issue by developing the concept lifestyled business practice. Through a study of criminal gangs in Sweden we contribute by developing three main entanglements of business practice; hedonic structures, stylized intelligence and sonic monetizationThe entanglement of business and consumption practices have been neglected in prior consumer research. We address this issue by developing the concept lifestyled business practice. Through a study of criminal gangs in Sweden we contribute by developing three main entanglements of business practice; hedonic structures, stylized intelligence and sonic monetization

Cannabis use, mental health, and problematic Internet use in Quebec : A study protocol

Background Problematic Internet use is characterized by excessive use of online platforms that can result in social isolation, family problems, psychological distress, and even suicide. Problematic Internet use has been associated with cannabis use disorder, however knowledge on the adult population remains limited. In Quebec, cannabis use has significatively increased since 2018, and it is associ

The Consultant's Quest : Expansion Game for the Opera The Prophecies

How can ludic play frame and assist the participants' interactions in an immersive opera? The Consultant's Quest was developed as an artistic response to the idea and the challenge of integrating articulated game-playing as a both methodic and affective instrument in relation to operatic elements. Presented as a card-driven board game in connection to the operatic experience The Prophecies, The CoHow can ludic play frame and assist the participants' interactions in an immersive opera? The Consultant's Quest was developed as an artistic response to the idea and the challenge of integrating articulated game-playing as a both methodic and affective instrument in relation to operatic elements. Presented as a card-driven board game in connection to the operatic experience The Prophecies, The Co

Interactive effects of physical fitness and body mass index on risk of stroke : A national cohort study

BACKGROUND: High body mass index (BMI) and low physical fitness are risk factors for stroke, but their interactive effects are unknown. Elucidation of interactions between these modifiable risk factors can help inform preventive interventions in susceptible subgroups.METHODS: National cohort study of all 1,547,294 military conscripts in Sweden during 1969-1997 (97-98% of all 18-year-old males). St

Clinical features of registry-ascertained alcohol use disorders that reflect familial risk

Background: Alcohol Use Disorder (AUD) is clinically heterogeneous. Using a large epidemiological sample ascertained via public registries, is it possible to identify clinical and historical features of AUD that reflect familial risk? Methods: Using registration in national medical, legal or pharmacy registries, we identified four kinds of relative pairs (n = 683,223) starting with a proband with

Long-term effects of neighbourhood deprivation on diabetes risk : Quasi-experimental evidence from a refugee dispersal policy in Sweden

Background: Although studies have shown associations between neighbourhood quality and chronic disease outcomes, such associations are potentially confounded by the selection of different types of people into different neighbourhood environments. We sought to identify the causal effects of neighbourhood deprivation on type 2 diabetes risk, by comparing refugees in Sweden who were actively disperse

Familial risks of glomerulonephritis : a nationwide family study in Sweden

Objective: Familial risks of glomerulonephritis (acute, chronic and unspecified glomerulonephritis) have not been studied. This study aims to determine the familial risks of glomerulonephritis. Methods: Individuals born from1932 onwards diagnosed with glomerulonephritis (acute [n = 7011], chronic [n = 10,242] and unspecified glomerulonephritis [n = 5762]) were included. The familial risk (Standard