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There is an urgent need for society to find more effective ways to reduce the impact of disastrous events. One way is to proactively increase actors’ response capability. Capability assessments play an essential role in these disaster risk management efforts. Currently, capability is assessed using indicator and index methods that focus on available resources. Such methods may not provide the best
The Swedish crime genre is experiencing an intense period of change at the moment. Crime writers appear to be at the forefront when it comes to the issue of how to reach international audiences, how to promote books and author’s brands through events, and how to create a successful life as a writer. The working conditions, as well as the content of what is sold and marketed to the readers have gon
The fact that deep learning based algorithms used for digital pathology tend to overfit to the site of the training data is well-known. Since an algorithm that does not generalize is not very useful, we have in this work studied how different data augmentation techniques can reduce this problem but also how data from different sites can be normalized to each other. For both of these approaches we
One way of valorizing the lignin waste stream from the pulp and paper industries is depolymerizing it into low-molecular-mass compounds (LMMC). However, a common problem in the depolymerization of Kraft lignin is the low yields of small aromatic molecules obtained. In the present work, the combination of the repeated depolymerization of lignin and the separation of LMMC from depolymerized lignin t
This study had two aims: first to describe, using both descriptive statistics and quantitative content analysis, the noise environment in an ICU patient room over one day, a patient's physical status during the same day and early signs of ICU delirium; second, to describe, using qualitative content analysis, patients' recall of the noise environment in the ICU patient room. The final study group c
When combined with the huge collecting area of the ELT, MOSAIC will be the most effective and flexible Multi-Object Spectrograph (MOS) facility in the world, having both a high multiplex and a multi-Integral Field Unit (Multi-IFU) capability. It will be the fastest way to spectroscopically follow-up the faintest sources, probing the reionisation epoch, as well as evaluating the evolution of the dw
We investigate the Ca(2+)-triggered fusion of lipid vesicles site-selectively tethered to a DNA-modified supported lipid bilayer array, with the DNA strands designed such that hybridization occurs in a zipperlike fashion. Prior to the addition of Ca(2+), which is observed to induce docking and subsequent fusion (within 200 ms), the vesicles display lateral mobility determined by the number of teth
Seawater intrusion in coastal aquifers is a widespread and serious problem in many parts of the world. Groundwater degradation due to seawater intrusion is often accentuated in small island aquifers due to overpumping or limited replenishing amounts of precipitation. Seawater intrusion and groundwater dynamics in a small limestone aquifer on Yoron Island, Japan, were investigated. Observations in
Although Scandinavia is arguably peripheral in the global literary system, it nevertheless holds a surprisingly prominent position in the field of translation, Swedish and Danish being among the ten most translated languages in the world (Lindqvist, 2015). What literature is selected for translation and introduction into new linguistic contexts is not a coincidence, but has to do with economic fac
The concept of acoustic comfort is hardly defined and used to refer to conditions of low noise levels or annoyance based on standardized descriptors. Airborne and impact sound measurements are used to rate acoustic comfort in dwellings, but they often do not express human perception of noise or comfort. If the descriptors are statistically associated with self-reported responses, they can be used
To determine the effect of erythropoietin (EPO) on patency the haemodynamics and morphology in haemodialysis fistula/graft were prospectively assessed using ultrasonographic two-dimensional imaging and colour flow Doppler together with pulsed Doppler, prior to and during partial correction of anaemia with EPO. Nineteen radiocephalic fistula and 11 loop grafts in 30 patients on routine maintenance
Blood-brain barrier (BBB) dysfunction might be an important component of many neurodegenerative disorders. In this study, we investigated its role in dementia using large clinical cohorts. The cerebrospinal fluid (CSF)/plasma albumin ratio (Qalb), an indicator of BBB (and blood-CSF barrier) permeability, was measured in a total of 1015 individuals. The ratio was increased in patients with Alzheime
In this paper, we investigate the security of SNOW-V, demonstrating two guess-and-determine (GnD) attacks against the full version with complexities 2384 and 2378, respectively, and one distinguishing attack against a reduced variant with complexity 2303 . Our GnD attacks use enumeration with recursion to explore valid guessing paths, and try to truncate as many invalid guessing paths as possible
Importance: Local steroid injection is commonly used in treating patients with idiopathic carpal tunnel syndrome, but evidence regarding long-term efficacy is lacking. Objective: To assess the long-term treatment effects of local steroid injection for carpal tunnel syndrome. Design, Setting, and Participants: This exploratory 5-year extended follow-up of a double-blind, placebo-controlled randomiz
Respiratory disorders are common among people with intellectual disabilities (ID). However, few studies have investigated these disorders among older people with ID. We identified 7936 people, aged 55+ years, with ID and a reference cohort from the general population. Data on diagnoses of chronic respiratory disorders, with a focus on asthma and chronic obstructive pulmonary disease (COPD), were c
Background Many microbial eukaryotes have evolved anaerobic alternatives to mitochondria known as mitochondrion-related organelles (MROs). Yet, only a few of these have been experimentally investigated. Here we report an RNA-seq-based reconstruction of the MRO proteome of Pygsuia biforma, an anaerobic representative of an unexplored deep-branching eukaryotic lineage. Results Pygsuia's MRO has a co
Solen är den primära källan för jordens klimatsystem, som driver den atmosfäriska och oceana cirkulationen. Förutom att solens varierande instrålning påverkan jordens klimat, så bestämmer instrålningen även den atmosfäriska produktionen av kosmogena partiklar (t. ex. 10Be, 14C, 36Cl) som sedan lagras i diverse klimatarkiv på jorden. Förändringar i solinstrålningen över tid kan därför undersökas ocThe Sun is the primary source for Earth’s climate system. Its fluctuations in irradiance are also known to have an impact on climate. In addition, changes in solar activity modulate the atmospheric production rates of cosmogenic radionuclides (e.g. 10Be, 14C, 36Cl) that all eventually deposit to different environmental archives. The signal of the changing solar activity through time can thus be re
Glutamate is an important factor in the mechanisms of neuronal damage following cerebral ischemia. Blockade of one type of glutamate receptor, the N-methyl-D-aspartate (NMDA) receptor, decreases brain infarct size in experimental models of permanent focal ischemia, but protection in models of transient reversible ischemia is ambiguous. We investigated the effect of the noncompetitive NMDA receptor
European infrastructure managers (IMs) create annual timetables for trains that will run during a year. Freight trains in Sweden often deviate from this by being added, cancelled, delayed or early, resulting in increased costs for IMs and railway undertakings (RUs). We investigate the frequency of and causes for these deviations, using one year of operational data for 48,000 trains, and 15 stakeho
