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Background: Breathlessness on exertion is a common, distressing, and limiting symptom that can be quantified on incremental cardiopulmonary exercise testing (CPET) using normative reference equations. Research Question: Is the breathlessness abnormality best uncovered and assessed at symptom limitation (peak exercise) compared with submaximal exercise intensities? Study Design and Methods: This wa

Introduction: Wearable sensors measuring bodily movements used in free-living conditions may help predict falls in older persons. Assessing their use in this context is essential to identify potential challenges related to fall risk screening. Therefore, this study aimed to assess the feasibility of conducting a prospective study comparing self-rated and wearable sensor-based measures for the asse

PURPOSE: The systolic blood pressure (SBP) response to exercise reflects cardiovascular health, with both exaggerated and blunted responses linked to adverse outcomes. Prior studies relied typically on peak SBP or two-point slopes for evaluation. We aimed to identify distinct SBP responses from full times-series recorded during maximal, graded exercise and assess their clinical determinants and pr

This chapter analyses the role that 'ordre public' and morality exceptions can play in the granting of patents on inventions in the field of human germline editing and the consequences of this policy option. In order to provide the context for such an analysis, the chapter will, first, provide an overview of the current patent landscape for relevant genome editing technologies, drawing attention t

BACKGROUND: Treatment for breast cancer poses major challenges and leads to a variety of side-effects and problems that affect life for a long time. Experiences and symptoms vary, and research indicates a lack of structures for ensuring individualized rehabilitation. This qualitative focus group study aims to explore the experience of women with BC after participating in a complex randomized contr

Very few people around us know the meaning of the word cavitation, except from those who saw the movie "The Hunt for Red October" and can relate cavitation to Sean Connery in a submarine. Some of them know that it corresponds to the formation of bubbles, due to a pressure drop, and causes erosion and noise. However, cavitation is much more complex. A large amount of research work has been done ove

Attention Restoration Theory point to nature as a particularly good candidate for restoring the ability to focus and inhibit distractions. However, little effort has been directed to elaborating on what makes nature's visual pattern unique for restoration purposes. One suggested explanation is the fractal properties of natural patterns (Hagerhall, 2005). Both perception studies (Hagerhall et al.,

Läkartidningen 5-6/2025. Egenreferat. Dödshjälp, det vill säga eutanasi och läkarassisterat självmord, är olaglig i Sverige, men debatten om legalisering är fortsatt aktuell.Läkarförbundet genomförde 2021 en enkätundersökning om läkarkårens inställning till dödshjälp. 41 procent av de svarande ansåg att dödshjälp bör tillåtas enligt svensk lag (medan 34 procent motsatte sig detta), men endast 29 p

Recent research projects have targeted the hitherto limited inclusion of the subsurface and its geo-resources in spatial planning in Sweden. The UNDER project focuses on the societal implications of using the concept of geosystem services to support planning practices. The concept of geosystem services has been described as the contributions to human well-being from the abiotic world or from the s

Background People with serious respiratory illness frequently have a high symptom burden and may be prescribed supplemental oxygen therapy with the aims of reducing the severity of breathlessness and improving health-related quality of life (HRQoL). This systematic review and meta-analysis aimed to assess the effectiveness of oxygen therapy versus no oxygen on 1) breathlessness, 2) HRQoL and 3) ad